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Chapter 9 Cellular Respiration: Harvesting Chemical Energy Flashcards

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609139128catabolic pathwaysmetabolic pathways that release stored energy by breaking down complex molecules; do not directly move flagella, pump solutes across membranes, polymerize monomers, or perform other cellular work
609139129fermentationCatabolic process; a partial degradation of sugars that occurs without the help of oxygen
609139130cellular respirationthe most prevalent and efficient catabolic pathway; oxygen is consumed as a reactant along with the organic fuel; mitochondria in eukayrotic cells; replenishes the ATP supply by powering the Phosphorylation of ADP
609139131triphosphate tailon ATP; chemical equivalent of a loaded spring; the close packing of the three negatively charged phosphate groups is an unstable, energy-storing arrangement. releases energy by losing the terminal phosphate
609139132phosphorlylationa compound that has had a transfer of a phosphate group from ATP to other compounds; primes a molecule to undergo some kind of change that performs work, and the molecule loses its phosphate group in the process
609139133Phosphate group transferthe mechanism responsible for most types of cellular work; Enzymes shift a phosphate group from ATP to some other molecule, and this phosphorylated molecule undergoes a change that performs work ex-active transport and motor proteins
609139134oxidation reduction reactions (redox)release energy stored in food molecules when electrons move closer to electronegative atoms, and this energy is used to synthesize ATP; transfer electrons or covalent sharing; in moving an electron from less elecneg. to more elecneg, chemical energy is released
609139135oxidationthe loss of electrons from one substance in a redox reaction
609139136reductionthe addition of electrons to another substance
609139137reducing agentin a redox reaction, this substance is the electron donor (usually hydrogen)
609139138oxidizing agentin a redox reaction, this substance is the electron acceptor; oxygen is best because its most electronegative
609139139burningthe rapid oxidation of fuel accompanied by an enormous release of energy as heat; activated when enzymes lower barrier of activation energy
609139140NAD+ (nicotinamide adenine dinucleotide)coenzyme that functions as an oxidizing agent during respiration; electon acceptor; consists of two nucleotides joined together
609139141dehydrogenasesenzymes that remove a pair of hydrogen atoms from the substrate, a sugar or some other fuel; delivers these 2e's to NAD+
609139142NADHthe reduced form of NAD+ that is electrically neutral; electrons transferred lose very little PE; represents stored energy that can be tapped to make ATP when the electrons complete their "fall" from NADH to oxygen
609139143Nicotinamidea nitrogenous base not found in DNA or RNA
609139144ETC (electron transport chain)of a number of molecules, mostly proteins, built into the inner membrane of a mitochondrion; accepts electrons from NADH and FADH2 and passes these electrons from one molecule to another; uses some of the released energy in a form that pumps H+ against its concentration gradient; rest released as heat;
609139145explosionwhen oxygen captures the NADH electrons along with hydrogen nuclei to form water; an exergonic reacgition that releases a large amount of energy
609139146terminal electron accepteroxygen; instead of explosive energy being released and wasted in a single explosive step, electrons cascade down the chain from one carrier molecule to the next, losing a small amount of energy with each step until they finally reach it; has a very great affinity for electrons and pulls them like gravity
609139147glycolysisa metabolic process that breaks down glucose into 2 pyruvate molecules and release energy for the body in the form of ATP; occurs in cytosol; catabloic pathway; means "splitting of sugar,"; no CO2 is released
609139148pyruvateOrganic compound with a backbone of three carbon atoms. Two molecules form as end products of glycolysis; crosses the double membrane of the mitochondrion to enter the matrix, where the Krebs cycle decomposes it to carbon dioxide; the ionized form of a three-carbon acid
609139149NADH (or) FADH2transfers electrons from molecules undergoing glycolysis and the Krebs cycle to electron transport chains, which are built into the inner mitochondrial membrane
609139150Krebs cyclein all plants and animals: enzymatic reactions in mitochondrial matrix after glycolysis involving oxidative metabolism of acetyl compounds to produce high-energy phosphate compounds; catabolic pathway; releases less than 1/4 of the chemical energy stored in glucose
609139152oxidative phosphorylationThe mode of ATP synthesis where energy released at each step of the ETC is stored in a form the mitochondrion can use to make ATP; powered by the redox reactions that transfer electrons from food to oxygen; occurs in the inner membrane of the mitochondrion ; accounts for almost 90% of the ATP generated by respiration
609139154substrate-level phosphorylationmechanism in a few of the reactions of glycolysis and the krebs cycle where A smaller amount of ATP is directly formed This mode of ATP synthesis occurs when an enzyme transfers a phosphate group from a Bsubstrate molecule to ADP
609139156Bsubstrate moleculean organic molecule generated during the catabolism of glucose
609139158phosphoenolpyruvateSome ATP is made by direct enzymatic transfer of a phosphate group from a this phosphate donor to ADP; formed from the breakdown of sugar during glycolysis
609139159glucosea six-carbon sugar; split into two three-carbon sugars that are then oxidized and their remaining atoms rearranged to form two molecules of pyruvate
609139160pyruvic acidthree carbon acid that is inoized into pyruvate
609139161junction stepstep between Glycolysis and Krebs cycle; upon entering the mitochondrion, pyruvate is first converted to a compound called acetyl coenzyme A, or acetyl CoA
609139162Chemiosmosisthe ETC makes no ATP directly, so the mitochondrion couples ETC and energy release to ATP synthesis with this mechanism;the process where an H+ gradient across a membrane couples the redox reactions of the electron transport chain to ATP synthesis
609139163ATP synthaseresides in mitochondrial and chloroplast membranes of eukaryotes and in plasma membranes of prokaryotes; synthase uses the energy of an existing ion gradient to phosphorylate ADP to ATP; its power is a difference in the concentration of H+ (PH) on opposite sides of the inner mitochondrial membrane pumped by ETC; has three main parts: a rotor, a rod, and a knob; oxidative
609139164cylindrical rotorhydrogen ions flow through this down their gradient and cause the attatched rod to rotate a stream to a watermill
609139165knobportrudes into the mitochondrial matrix; spinnig rod changes this and activates catalytic sites where ADP and inorganic phosphate combine to make ATP
609139166proton motive forceThe potential energy stored in the form of an electrochemical gradient, generated by the pumping of hydrogen ions across biological membranes during chemiosmosis.
609139167Fermentationan extension of glycolysis that can generate ATP solely by substrate-level phosphorylation -- as long as there is a sufficient supply of NAD+ to accept electrons during the oxidation step of glycolysis
609139168Anaerobic catabolismglucose is broken down in the absence of oxygen in the cytoplasm through a series of chemical reactions, first into pyruvic acid and then into lactic acid; fermentation
609139169aerobic catabolismNAD+ is recycled productively from NADH by the transfer of electrons to the electron transport chain
609139170alcoholic fermentationreleases carbon dioxide from the pyruvate, which is converted to the two-carbon compound acetaldehyde; acetaldehyde is then reduced by NADH to ethanol. This regenerates the supply of NAD+ needed for glycolysis. ex- yeast
609139171lactic acid fermentationpyruvate is reduced directly by NADH to form lactate as a waste product, with no release of CO2
609139172lactateionized form of lactic acid; accumulates and causes fatigue and pain, but is taken from blood to liver and converted back to pyruvate by liver cells
609139173facultative anaerobesorganisms, including yeasts and many bacteria, can make enough ATP to survive using either fermentation or respiration; also our muscles function as these on the cellular level
609139174deaminationto use excess proteins in body for cellular respiration, their ammino groups are removed in this process; the nitrogen base is secreated as urea or ammonia
609139175beta oxidationa metabolic sequence that breaks the fatty acids down to two-carbon fragments, which enter the Krebs cycle as acetyl CoA
609139176phosphofructokinasepacemaker of cell respiration; It is stimulated by AMP , but it is inhibited by ATP and by citrate

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