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Concepts of Genetics Chapter 2 Flashcards

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3311458511chromosomein prokaryotes, a DNA molecule containing the organism's genome; in eukaryotes, a DNA molecule complexed with RNA and proteins to form a threadlike structure containing genetic information arranged in a linear sequence; a structure that is visible during mitosis and meiosis0
3311458512mitosisa form of cell division producing two progeny cells identical genetically to the progenitor cell - that is, the production of two cells from one, each having the same chromosome complement as the parent cell1
3311458513meiosisthe process of cell division in gemetogenesis or sporogenesis during which the diploid number of chromosomes is reduced to the haploid number2
3311458514gamete/sporea specialized reproductive cell with a haploid number of chromosomes3
3311458515chromatinthe complex of DNA, RNA, histones and nonhistone proteins that make up uncoiled chromosomes, characteristic of eukaryotic interphase nucleus4
3311458516eukaryotesorganisms having true nuclei and membraneous organelles and whose cells divide by mitosis and meiosis5
3311458517nucleusthe membrane-bound cytoplasmic organelles of eukaryotic cells that contains the chromosomes and nucleolus6
3311458518nucleolusthe nuclear site of ribosome biosynthesis and assembly; usually associated with or formed in association with the DNA compromising the nucleolar organizer region.7
3311458519nucleolar organizer region (NOR)a chromosomal region containing the genes for rRNA; most often found in physical association with the nucleolus8
3311458520prokaryoteorganisms lacking nuclear membranes and true chromosomes. Bacteria and blue-green algae are examples of these.9
3311458521nucleoidthe DNA-containing region within the cytoplasm in prokaryotic cells10
3311458522endoplasmic reticulum (ER)a membranous organelle system in the cytoplasm of eukaryotic cells. In rough __, the outer surface of the membranes is ribosome-studded; in smooth __, it is not11
3311458523ribosomea ribonucleoprotein organelle consisting of two subunits, each containing RNA and protein molecules. They are the site of translation of mRNA codons into the amino acid sequence of a polypeptide chain12
3311458524mitochondriathe so-called power house of the cell - a self-reproducing, DNA-containing, cytoplasmic organelle in eukaryotes involved in generating the high-energy compound ATP13
3311458525chloroplasta self-replicating cytoplasmic organelle containing chlorophyll and the site of photosynthesis14
3311458526endosymbiont hypothesisthe proposal that self-replicating cellular organelles such as mitochondria and chloroplasts were originally free-living organisms that entered into a symbiotic relationship with nucleated cells15
3311458527centriolea cytoplasmic organelle composed of nine groups of microtubules, generally arranged in triplets. They function in the generation of cilia and flagella and serve as foci for the spindle in cell division16
3311458528centrosomeregion of the cytoplasm containing a pair of centrioles17
3311458529spindle fiberscytoplasmic fibrils formed during cell division that attach to and are involved with separation of chromatids at the anaphase stage of mitosis and meiosis as well as their movement toward opposite poles in the cell.18
3311458530centromerethe specialized heterochromatic chromosomal region at which sister chromatids remain attached after replication and the site to which spindle fibers attach to the chromosome during cell division. Location of these during the anaphase portion of cell division. Also known as the primary constriction19
3311458531diploid (2n)a condition in which each chromosome exists in pairs; having two of each chromosome20
3311458532homologous chromosomeschromosomes that synapse or pair during meiosis and that are identical with respect to their general loci and centromere placement21
3311458533karyotypethe chromosome complement of a cell or an individual. Often used to refer to the arrangement of metaphase chromosomes in a sequence according to length and centromere position22
3311458534haploid (n)a cell or an organism having one member of each pair of homologous chromosomes. Also referred to as the gametic chromosome number23
3311458535genomethe set of hereditary information encoded in the DNA of an organism, including both the protein-coding and non-protein-coding sequences24
3311458536locusthe site or place on a chromosome where a particular gene is located25
3311458537alleleone of the possible alternative forms of a gene, often distinguished from other alleles by phenotypic effects26
3311458538zygotethe diploid cell produced by the fusion of haploid gemetic nuclei27
3311458539karyokinesisthe process of nuclear division28
3311458540cytokinesisthe division or separation of the cytoplasm during mitosis or meiosis29
3311458541cell cyclethe sequence of groth phases of an individual cell; divided into G1, S, G2 and M. A cell may temporarily or permanently be withdrawn from it, in which case it is said to enter the G0 stage30
3311458542interphasein the cell cycle, the interval between divisions31
3311458543G0 phasea nondividing but metabolically active state that cells may enter from the G1 phase of the cell cycle32
3311458544cohesina protein complex that holds sister chromatids together during mitosis and meiosis and facilitates attachments of spindle fibers to kinetochores33
3311458545metaphasethe stage of cell division in which condensed chromosomes lie in a cnetral plane between the two poles of the cell and during which the chromosomes become attached to the spindle fibers34
3311458546kinetochorea fibrous structure with a size of about 400 nm, located within the centromere. It is the site of microtubule attachment during cell division35
3311458547shugoshinsa class of proteins involved in maintaining cohesion of the centromeres of sister chromatids during mitosis and meiosis.36
3311458548anaphasestage of mitosis or meiosis in which chromosomes begin moving to opposite poles of the cell37
3311458549disjunctionthe separation of chromosomes during the anaphase stage of cell division38
3311458550telophasethe stage of cell division in which the daughter chromosomes have reached the opposite poles of the cell and reverse the stages characteristic of prophase, re-forming the nuclear envelopes and uncoiling the chromosomes. Ends with cytokinesis, which divides the cytoplasm and splits the cell in two.39
3311458551cyclinin eukaryotic cells, a class of proteins that are synthesized and degraded in synchrony with the cell cycle and regulate passage through stages of the cycle40
3311458552G1 checkpointa point in the G1 phase of the cell cycle when a cell becomes committed to initiating DNA synthesis and continuing the cycle or withdraws into the G0 resting stage.41
3311458553crossing overthe exchange of chromosomal material (parts of chromosomal arms between homologous chromosomes by breakage and reunion. The exchange of material between nonsister chromatids during meiosis is the basis of genetic recmobination42
3311458554synapsisthe pairing of homologous chromosomes at meiosis43
3311458555bivalentssynapsed homologous chromosomes in the first phase of meiosis44
3311458556tetradthe four chromatids that make up paired homologs in the prophase of the first meiotic division. In eukaryotes, with a predominant haploid stage (some algae and fungi), a tetrad denotes the four haploid cells produced by a single meiotic division45
3311458557reductional divisionthe chromosome division that halves the number of centromeres and thus reduces the chromosome number by half. The first division of meiosis is an example.46
3311458558dyadthe products of tetrad separation or disjunction at meiotic prophase I. Each one consists of two sister chromatids joined at the centromere47
3311458559equational divisiona division stage where the number of centromeres is not reduced by half but where each chromosome is split into longitudinal halves that are distributed into two daughter cells. Chromosome division in mitosis and the second meiotic division are examples.48
3311458560chaismathe crossed strands of nonsister chromatids seen in diplotene of the first meiotic division. Regarded as the cytological evidence for exchange of chromosomal material, or crossing over49
3311458561nondisjunctiona cell division error in which homologous chromosomes (in meiosis) or the sister chromatids (in mitosis) fail to separate and migrate to opposite poles; responsible for defects such as monosomy and trisomy50
3311458562telophase Ithe stage in the first meiotic division when duplicated chromosomes reach the poles of the dividing cell51
3311458563anaphase Ithe stage in the first meiotic division during which members of homologous pairs of chromosomes separate from one another.52

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