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Critical Care Drugs Flashcards

OhioHealth Critical Care Fellowship

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94492996Adenosine Classantiarrhythmics0
94492997Adenosine Trade NameAdenocard, Adenoscan1
94493001Adenosine MOA• Restores normal sinus rhythm by interrupting re-entrant pathways in the AV node. • Slows conduction time through the AV node. • Also produces coronary artery vasodilation.2
94493010Adenosine Intended Action• Conversion of paroxysmal supraventricular tachycardia (PSVT) to normal sinus rhythm when vagal maneuvers are unsuccessful. • As a diagnostic agent (with noninvasive techniques) to assess myocardial perfusion defects occurring as a consequence of coronary artery disease.3
94493012Adenosine Side EffectsCNS: apprehension, dizziness, headache, head pressure, light-headedness. EENT: blurred vision, throat tightness. Resp: shortness of breath, chest pressure, hyperventilation. CV: facial flushing, transient arrhythmias, chest pain, hypotension, palpitations. GI: metallic taste, nausea. Derm: burning sensation, facial flushing, sweating. MS: neck and back pain. Neuro: numbness, tingling. Misc: heaviness in arms, pressure sensation in groin.4
94493015Argatroban Classanticoagulants - thrombin inhibitors5
94493161Argatroban Trade NameArgatroban6
94493163Argatroban MOAselectively inhibits free and clot-bound thrombin (direct thrombin inhibitor)7
94493164Argatroban Intended ActionArgatroban keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur while receiving heparin8
94493166Argatroban Side Effectsfeeling like you might pass out; easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; blood in your urine; black, bloody, or tarry stools; coughing up blood or vomit that looks like coffee grounds; any bleeding that will not stop; pain or burning when you urinate; sudden numbness or weakness, problems with vision, speech, or balance; sudden severe headache, confusion, sudden changes in your senses of taste or touch; fever, chills, body aches, flu symptoms; cough with yellow or green mucus, stabbing chest pain, feeling short of breath; slow heart rate, weak pulse, slow breathing (breathing may stop); or chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.9
94493167Amiodarone Classantiarrhythmics10
94493169Amiodarone Trade NameCordarone, Pacerone11
94493170Amiodarone MOAprolongs action potential phase 3 (class III antiarrhythmic)12
94493171Amiodarone Intended ActionAmiodarone is used to help keep the heart beating normally in people with life-threatening heart rhythm disorders of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). Amiodarone is used to treat ventricular tachycardia or ventricular fibrillation.13
94493172Amiodarone Side Effectsa new or a worsening irregular heartbeat pattern; fast, slow, or pounding heartbeats; feeling like you might pass out; wheezing, cough, chest pain, trouble breathing, coughing up blood; blurred vision, vision loss, headache or pain behind your eyes, sometimes with vomiting; feeling short of breath, even with mild exertion, swelling, rapid weight gain; weight loss, thinning hair, feeling too hot or too cold, increased sweating, irregular menstrual periods, swelling in your neck (goiter); numbness, burning, pain, or tingling in your hands or feet; or nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).14
94493173Atracurium Classneuromuscular blockers15
94493175Atracurium Trade NameTracrium16
94493176Atracurium MOAantagonizes motor endplate acetylcholine receptors (non-depolarizing neuromuscular blocker)17
94493180Atracurium Intended Actionused adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.18
94493181Atracurium Side EffectsSerious Reactions prolonged paralysis (long-term use) respiratory depression apnea malignant hyperthermia seizures (ICU pts) anaphylaxis/anaphylactoid rxn bronchospasm hypotension cardiac arrest arrhythmias Common Reactions skin flushing BP changes HR elevated19
94493264Atropine Classbelladona alkaloid20
94496294Atropine Trade NameAtroPen21
94496295Atropine MOAantagonizes acetylcholine receptors (anticholinergic)22
94496296Atropine Intended ActionAdministration prior to anesthesia to reduce or prevent secretions of respiratory tract; restoration of cardiac rate and arterial pressure in some situations23
94496298Atropine Side EffectsSerious Reactions anaphylaxis bradycardia, severe heat stroke Common Reactions headache xerostomia nausea insomnia dizziness restlessness blurred vision mydriasis constipation delirium tachycardia palpitations ataxia tremor dry hot skin24
94496299Cefazolin Class1st gen. cephalosporin25
94496300Cefazolin Trade NameAncef, Kefzol26
94496301Cefazolin MOAbactericidal; inhibits cell wall mucopeptide synthesis27
94496302Cefazolin Intended ActionCefazolin is used to treat many kinds of bacterial infections, including severe or life-threatening forms.28
94496303Cefazolin Side EffectsSerious Reactions neutropenia thrombocytopenia anaphylaxis Stevens-Johnson syndrome nephrotoxicity seizures Clostridium difficile associated diarrhea Common Reactions diarrhea rash vomiting nausea abdominal pain anorexia ALT, AST elevated urticaria thrombophlebitis29
94496304Cefepime Class4th gen. cephalosporin30
94496305Cefepime Trade NameMaxipime31
94496307Cefepime MOAbactericidal; inhibits cell wall mucopeptide synthesis32
94496310Cefepime Intended ActionCefepime injection is used to treat many kinds of bacterial infections, including severe or life-threatening forms.33
94496315Cefepime Side EffectsSerious Reactions anaphylaxis encephalopathy seizures non-convulsive status epilepticus leukopenia thrombocytopenia agranulocytosis anemia, hemolytic aplastic anemia hemorrhage Stevens-Johnson syndrome toxic epidermal necrolysis erythema multiforme Clostridium difficile associated diarrhea Common Reactions rash injection site rxn diarrhea hypophosphatemia ALT, AST elevated nausea34
94496316Ceftriaxone Class3rd gen. cephalosporin35
94496317Ceftriaxone Trade NameRocephin36
94496320Ceftriaxone MOAbactericidal; inhibits cell wall mucopeptide synthesis37
94496321Ceftriaxone Intended ActionCeftriaxone is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis.38
94496322Ceftriaxone Side EffectsSerious Reactions anaphylaxis bronchospasm Stevens-Johnson syndrome toxic epidermal necrolysis erythema multiforme serum sickness pneumonitis, hypersensitivity neutropenia leukopenia anemia, hemolytic thrombocytopenia hypoprothrombinemia agranulocytosis superinfection Clostridium difficile associated diarrhea colitis biliary/gallbladder sludge jaundice pancreatitis seizures nephrolithiasis lung/kidney Ca-ceftriaxone precipitate (neonates) Common Reactions local injection site rxn eosinophilia thrombocytosis ALT, AST elevated diarrhea leukopenia39
94496324Cisatracurium Classneuromusuclar blockers40
94496325Cisatracurium Trade NameNimbrex41
94496326Cisatracurium MOAantagonizes motor endplate acetylcholine receptors (non-depolarizing neuromuscular blocker)42
94496328Cisatracurium Intended ActionCisatracurium is given before general anesthesia in preparing you for surgery. Cisatracurium helps keep your body still during surgery. It also relaxes your throat so a breathing tube can be more easily inserted before the surgery.43
94496329Cistracurium Side EffectsSerious Reactions hypersensitivity rxn anaphylaxis/anaphylactoid rxn bronchospasm hypotension respiratory depression prolonged paralysis (long-term use) Common Reactions bradycardia hypotension flushing bronchospasm rash44
94496330Dexmedetomidine Classsedation45
94496736Dexmedetomidine Trade NamePrecedex46
94496790Dexmedetomidine MOAproduces centrally mediated sympatholytic, sedative and analgesic effects (selective alpha-2 adrenergic agonist)47
94496834Dexmedetomidine Intended ActionRelaxes your muscles and makes you sleepy while you are on a ventilator or during intubation (having a breathing tube put into your throat). Also used before or during surgery or other procedures.48
94496836Dexmedetomidine Side EffectsSerious Reactions hypotension bradycardia, severe sinus arrest arrhythmias atrial fibrillation pleural effusion pulmonary edema respiratory depression respiratory acidosis respiratory failure ARDS bronchospasm hyperkalemia adrenal insufficiency leukocytosis acute renal failure hypovolemia/dehydration hyperpyrexia Common Reactions hypotension HTN nausea bradycardia atrial fibrillation fever xerostomia vomiting hypovolemia atelectasis hypoxia pleural effusion agitation tachycardia anemia hyperthermia rigors hyperglycemia hemorrhage pain oliguria thirst respiratory depression acidosis49
94496837Diazepam Classbenzodiazepine50
94496838Diazepam Trade NameValium, Diastat51
94496859Diazepam MOAbinds to benzodiazepine receptors; enhances GABA effects52
94496862Diazepam Intended ActionTreats anxiety, muscle spasms, seizures, and other medical conditions.53
94496863Diazepam Side Effectserious Reactions respiratory depression dependency, abuse seizures suicidality bradycardia hypotension, severe syncope cardiovascular collapse blood dyscrasias jaundice CNS stimulation, paradoxical withdrawal sx if abrupt D/C (long-term use) Common Reactions drowsiness fatigue asthenia ataxia venous thrombosis (IM or IV use) phlebitis (IM or IV use) confusion depression dysarthria headache tremor dystonia amnesia urinary retention constipation nausea incontinence diplopia dizziness irritability disinhibition libido changes rash xerostomia sialorrhea menstrual irregularities hypotension ALT, AST elevated54
94496864Dobutamine Classinotropes/pressors55
94496865Dobutamine Trade NameDobutrex56
94496868Dobutamine MOAstimulates beta-1 adrenergic receptors57
94496874Dobutamine Intended ActionDobutamine is used for short term treatment of patients with cardiac decompensation.58
94496875Dobutamine Side EffectsSerious Reactions HTN tachycardia PVCs hypotension, severe ventricular tachycardia thrombocytopenia hypokalemia bronchospasm Common Reactions HTN tachycardia PVCs nausea headache angina palpitations dyspnea phlebitis59
94496876Dopamine Classinotropes/pressors - catelcholamine60
94496877Dopamine Trade Namen/a61
94496878Dopamine MOAstimulates alpha and beta-1 adrenergic and dopaminergic receptors; produces inotropic, chronotropic, renal/splanchnic vasodilatory (at low doses), and pressor (at high doses) effects62
94496879Dopamine Intended ActionTreats circulation problems caused by heart attack, heart failure, kidney failure, low blood pressure, or surgery.63
94496880Dopamine Side EffectsSerious Reactions anaphylaxis hypotension bronchospasm atrial fibrillation extravasation necrosis gangrene ventricular arrhythmias (high dose use) Common Reactions tachycardia headache nausea vomiting anxiety HTN cardiac conduction disturbance vasoconstriction angina palpitations azotemia dyspnea64
94496931Epinephrine Classinotropes/pressors, antiarrhythmics, anaphylaxis65
94496932Epinephrine Trade NameEpiPen, Adrenalin66
94496933Epinephrine MOAstimulates alpha and beta adrenergic receptors (sympathomimetic)67
94497029Epinephrine Intended ActionEpinephrine is a chemical that narrows blood vessels and opens airways in the lungs. These effects can reverse severe low blood pressure, wheezing, severe skin itching, hives, and other symptoms of an allergic reaction.68
94497030Epinephrine Side EffectsSerious Reactions respiratory difficulty pulmonary edema arrhythmias HTN cerebral hemorrhage tissue necrosis (SC or IM use) Common Reactions palpitations tachycardia nausea/vomiting pallor diaphoresis dizziness weakness tremor headache apprehension nervousness anxiety restlessness69
94497063Eptifibatide Classantiplatelets70
94497064Eptifibatide Trade NameIntegrilin71
94497448Eptifibatide MOAreversibly binds to platelet glycoprotein IIb/IIIa receptors, reducing platelet aggregation72
94497465Eptifibatide Intended ActionEptifibatide is used to prevent blood clots or heart attack in people with severe chest pain or other conditions, and in those who are undergoing a procedure called angioplasty (to open blocked arteries).73
94497466Eptifibatide Side EffectsSerious Reactions bleeding, severe intracranial hemorrhage thrombocytopenia thrombocytopenia, autoimmune anaphylaxis Common Reactions bleeding hypotension74
94497467Esmolol Classbeta-blockers, antiarrhythmics75
94497468Esmolol Trade NameBrevibloc76
94497469Esmolol MOAselectively antagonizes beta-1 adrenergic receptors77
94497470Esmolol Intended ActionEsmolol is used for the rapid control of ventricular rate.78
94497471Esmolol Side EffectsSerious Reactions bronchospasm hypotension, severe cardiac failure seizures Common Reactions hypotension infusion site rxn nausea dizziness somnolence confusion headache agitation79
94497472Etomidate Classanesthetic80
94497548Etomidate Trade NameAmidate81
94497550Etomidate MOAexact mechanism of action unknown; may have GABA-like effects, depresses brain stem reticular formation activity and produces hypnosis82
94497558Etomidate Intended Actioninduction of general anaesthesia and for sedation[1] for short procedures such as reduction of dislocated joints, tracheal intubation and cardioversion.83
94497656Etomidate Side EffectsSerious Reactions shock Common Reactions myoclonic movements, transient injection site pain tonic movements, transient averting movements nausea vomiting apnea84
94497987Fentanyl Classopioid sedation, anesthesia adjunct85
94498018Fentanyl Trade NameDuragesic, Sublimaze86
94498020Fentanyl MOAbinds to various opioid receptors, producing analgesia and sedation (opioid agonist)87
94498021Fentanyl Intended ActionTreats severe, ongoing pain that cannot be controlled with other medicines. This medicine is a narcotic pain reliever.88
94498023Fentanyl Side EffectsSerious Reactions respiratory depression respiratory arrest dependency, abuse bradycardia, severe hypotension, severe anaphylaxis laryngospasm bronchoconstriction muscle rigidity, severe cardiac arrest circulatory collapse arrhythmias ICP incr. delirium seizures paralytic ileus Common Reactions somnolence nausea vomiting confusion asthenia constipation xerostomia diaphoresis dizziness urinary retention nervousness euphoria hallucinations dyspnea pruritus hypotension bradycardia muscle rigidity biliary spasm impaired coordination89
94498024Fluconazole Classantifungal90
94498025Fluconazole Trade NameDiflucan91
94499620Fluconazole MOAinhibits cytochrome p450 and sterol C-14 alpha-demethylation92
94499621Fluconazole Intended ActionFluconazole is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood. Fluconazole is also used to prevent fungal infection in people with weak immune systems caused by cancer treatment, bone marrow transplant, or diseases such as AIDS.93
94499623Fluconazole Side EffectsSerious Reactions hepatotoxicity seizures leukopenia agranulocytosis thrombocytopenia angioedema anaphylaxis Stevens-Johnson syndrome toxic epidermal necrolysis QT prolongation torsades de pointes Common Reactions nausea headache rash vomiting abdominal pain diarrhea dyspepsia taste changes dizziness ALT, AST elevated94
94499624Furosemide Classloop diuretic95
94499625Furosemide Trade NameLasix96
94499628Furosemide MOAinhibits loop of Henle and proximal and distal convoluted tubule sodium and chloride resorption97
94499629Furosemide Intended ActionFurosemide treats fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. This medication is also used to treat high blood pressure (hypertension).98
94499630Furosemide Side EffectsSerious Reactions hypokalemia, severe electrolyte imbalance, severe metabolic alkalosis hypovolemia/dehydration ototoxicity thrombocytopenia anemia, hemolytic aplastic anemia leukopenia agranulocytosis anaphylaxis vasculitis interstitial nephritis necrotizing angiitis erythema multiforme exfoliative dermatitis Stevens-Johnson syndrome toxic epidermal necrolysis pancreatitis cholestatic jaundice SLE exacerbation thrombosis eosinophilia rash w/ eosinophilia and systemic sx exanthematous pustulosis, acute generalized Common Reactions urinary frequency dizziness nausea/vomiting weakness muscle cramps hypokalemia hypomagnesemia hypotension, orthostatic ALT, AST elevated blurred vision anorexia abdominal cramps diarrhea pruritus rash hyperuricemia hyperglycemia hypocalcemia tinnitus paresthesia photosensitivity cholesterol incr. triglycerides incr.99
94499631Haloperidol Class1st gen. antipsychotic100
94499632Haloperidol Trade NameHaldol101
94499633Haloperidol MOAexact mechanism of action unknown; selectively antagonizes dopamine D2 receptors (butyrophenone)102
94499634Haloperidol Intended ActionHaloperidol is used to treat schizophrenia. It is also used to control motor and speech tics in people with Tourette's syndrome.103
94499638Haloperidol Side EffectsSerious Reactions extrapyramidal sx, severe tardive dyskinesia dystonia hyperpyrexia heat stroke neuroleptic malignant syndrome pneumonia hypotension HTN QT prolongation torsades de pointes arrhythmias sudden death hyponatremia seizures hepatic impairment leukopenia neutropenia agranulocytosis cataracts retinopathy withdrawal sx if abrupt D/C (long-term use) Common Reactions extrapyramidal sx tardive dyskinesia akathisia insomnia anxiety drowsiness lethargy weight changes anticholinergic effects gynecomastia breast tenderness galactorrhea menstrual irregularities photosensitivity104
94499639Heparin Classanticoagulant105
94499640Heparin Trade NamePosiFlush106
94499643Heparin MOAacts at multiple sites in coagulation process; binds to antithrombin III, catalyzing inactivation of thrombin and other clotting factors107
94499645Heparin Intended ActionHeparin is an anticoagulant (blood thinner) that prevents the formation of blood clots.108
94499646Heparin Side EffectsSerious Reactions hemorrhage thrombocytopenia, severe HIT/HITT incl. delayed onset hypersensitivity rxn anaphylactoid rxn neonatal gasping syndrome (benzyl alcohol-containing INJ forms) Common Reactions bleeding thrombocytopenia prolonged clotting time local injection site rxn hypersensitivity rxn urticaria fever rigors ALT, AST elevated osteoporosis (long-term use)109
94499648Labetalol Classbeta-blocker110
94499649Labetalol Trade NameTrandate111
94499650Labetalol MOAselectively antagonizes alpha-1 adrenergic receptors; antagonizes beta-1 and beta-2 adrenergic receptors (selective alpha and non-selective beta blocker)112
94499651Labetalol Intended ActionLabetalol is used to treat hypertension (high blood pressure).113
94499652Labetalol Side EffectsSerious Reactions CHF bradycardia, severe syncope heart block angina exacerbation if abrupt D/C MI if abrupt D/C ventricular arrhythmia during tx and if abrupt D/C Raynaud phenomenon bronchospasm lupus erythematosus hepatotoxicity hypersensitivity rxn anaphylactoid rxn intraoperative floppy iris syndrome Common Reactions hypotension, orthostatic (IV use) dizziness paresthesia nausea/vomiting BUN, Cr elevated fatigue dyspepsia rhinitis headache ejaculatory dysfxn dyspnea edema114
94499657Levofloxacin Classfluoroquinolone115
94499658Levofloxacin Trade NameLevaquin116
94499659Levofloxacin MOAbactericidal; inhibits DNA gyrase and topoisomerase IV117
94499732Levofloxacin Intended ActionLevofloxacin is used to treat bacterial infections of the skin, sinuses, kidneys, bladder, or prostate. Levofloxacin is also used to treat bacterial infections that cause bronchitis or pneumonia, and to treat people who have been exposed to anthrax or plague.118
94499733Levofloxacin Side EffectsSerious Reactions anaphylaxis hypersensitivity rxn phototoxicity Clostridium difficile associated diarrhea superinfection ICP incr. seizures toxic psychosis depression suicidal ideation QT prolongation torsades de pointes skin rxn, severe vasculitis pneumonitis, hypersensitivity serum sickness nephrotoxicity hepatotoxicity myelosuppression blood dyscrasias peripheral neuropathy tendon rupture arthralgia/myalgia arthropathy (animal studies) myasthenia gravis exacerbation Common Reactions nausea headache diarrhea insomnia constipation dizziness abdominal pain vomiting dyspepsia tendinitis119
94500003Lidocaine ClassAntiarrhythmics, Anesthetics120
94500004Lidocaine Trade NameXylocaine121
94500008Lidocaine MOAinhibits Na ion channels, stabilizing neuronal cell membranes and inhibiting nerve impulse initiation and conduction (amide local anesthetic); depresses action potential phase 0 (class IB antiarrhythmic)122
94500127Lidocaine Intended ActionLidocaine injection is used to numb an area of your body to help reduce pain or discomfort caused by invasive medical procedures such as surgery, needle punctures, or insertion of a catheter or breathing tube. Lidocaine injection is also given in an epidural (spinal block) to reduce the discomfort of contractions during labor. Lidocaine injection is sometimes used to treat irregular heart rhythms that may signal a possible heart attack.123
94500128Lidocaine Side EffectsSerious Reactions seizures respiratory arrest arrhythmia exacerbation status asthmaticus heart block bradycardia coma anaphylaxis methemoglobinemia Common Reactions injection site pain lightheadedness tremor confusion hypotension blurred vision tinnitus anxiety dizziness euphoria drowsiness lethargy nausea vomiting agitation hallucinations124
94500129Linezolid ClassAntibacterials125
94500130Linezolid Trade NameZyvox126
94500131Linezolid MOAbactericidal (strep) and bacteriostatic (staph, enterococci); binds to 50S ribosomal subunit, interfering w/ protein synthesis127
94500132Linezolid Intended ActionLinezolid is used to treat different types of bacterial infections, such pneumonia, skin infections, and infections that are resistant to other antibiotics.128
94500133Linezolid Side Effectsdiarrhea headache nausea HTN rash vomiting anemia thrombocytopenia fever URI129
94500134Lorazepam ClassBenzodiazepine130
94500135Lorazepam Trade NameAtivan131
94500136Lorazepam MOAbinds to benzodiazepine receptors; enhances GABA effects132
94500137Lorazepam Intended ActionLorazepam is used to treat anxiety disorders.133
94500139Lorazepam Side Effectssedation dizziness asthenia ataxia local injection site rxn respiratory depression hypoventilation (IV use) hypotension fatigue amnesia confusion disinhibition irritability libido changes menstrual irregularities diplopia dysarthria appetite changes constipation incontinence urinary retention dystonia ALT, AST elevated134
94500140Mannitol ClassOsmotic Diuretics (Neurological)135
94500151Mannitol Trade NameOsmitrol136
94500154Mannitol MOAelevates glomerular filtrate osmolarity (osmotic diuretic)137
94500155Mannitol Intended ActionMannitol is also used to reduce swelling and pressure inside the eye or around the brain.138
94500156Mannitol Side Effectsheadache nausea vomiting polyuria dizziness rash blurred vision thrombophlebitis fluid imbalance electrolyte disorders acidosis dehydration thirst urticaria hypotension tachycardia139
94500157Methylprednisolone ClassSystemic Corticosteroids140
94500161Methylprednisolone Trade NameMedrol141
94500162Methylprednisolone MOAexact mechanism of anti-inflammatory action unknown; inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects142
94500163Methylprednisolone Intended ActionMethylprednisolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.143
94500164Methylprednisolone Side Effectssodium and fluid retention sweating incr. headache vertigo insomnia nervousness mood swings edema muscle weakness BP elevated glucose intolerance petechiae/ecchymosis facial erythema menstrual irregularities hypokalemia IOP incr. impaired wound healing (long-term use) Cushing syndrome skin pigmentation abnormality hirsutism urticaria144
94500165Metoprolol ClassBeta Blocker145
94500168Metoprolol Trade NameLopressor, Toprol146
94501061Metoprolol MOAselectively antagonizes beta-1 adrenergic receptors147
94501062Metoprolol Intended ActionMetoprolol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.148
94501063Metoprolol Side Effectsfatigue dizziness diarrhea pruritus rash depression dyspnea bradycardia149
94501064Metoclopramide ClassProkinetics: N/V150
94501076Metoclopramide Trade NameReglan, Metozolv151
94501077Metoclopramide MOAexact mechanism of action unknown; sensitizes tissues to acetylcholine, stimulating upper GI tract motility; antagonizes central and peripheral dopamine receptors, producing antiemetic effects152
94501080Metoclopramide Intended ActionMetoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms. Metoclopramide is also used to treat slow gastric emptying in people with diabetes (also called diabetic gastroparesis), which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals.153
94501081Metoclopramide Side Effectsdrowsiness restlessness fatigue anxiety insomnia headache confusion dizziness depression extrapyramidal sx galactorrhea amenorrhea gynecomastia hyperprolactinemia impotence hyperaldosteronism fluid retention hypotension HTN bradycardia nausea diarrhea urinary frequency incontinence rash urticaria visual disturbance154
94501082Metronidazole ClassAntiparasitics155
94501083Metronidazole Trade NameFlagyl156
94501084Metronidazole MOAexact mechanism of action unknown; disrupts DNA and inhibits nucleic acid synthesis157
94501086Metronidazole Intended ActionMetronidazole is used to treat bacterial infections of the vagina, stomach, skin, joints, and respiratory tract. This medication will not treat a vaginal yeast infection.158
94501087Metronidazole Side Effectsnausea vomiting epigastric discomfort diarrhea metallic taste rash headache dizziness dark, red-brown urine candidiasis thrombophlebitis (IV use)159
94501088Midazolam ClassBenzodiazepine; Sedation160
94501089Midazolam Trade NameVersed161
94501094Midazolam MOAbinds to benzodiazepine receptors; enhances GABA effects162
94501095Midazolam Intended ActionMidazolam is used to sedate a person who is having a minor surgery, dental work, or other medical procedure.163
94501098Midazolam Side Effectssedation nausea vomiting injection site pain hiccups hypotension agitation dystonia amnesia diplopia disinhibition confusion ataxia weakness dysarthria euphoria rash164
94501099Naloxone ClassToxicity165
94501100Naloxone Trade nameNarcan166
94501101Naloxone MOAantagonizes various opioid receptors (opioid antagonist)167
94501105Naloxone Intended ActionNaloxone is used to reverse the effects of narcotic drugs used during surgery or to treat pain. Naloxone may also be used to treat narcotic drug overdose or to diagnose narcotic drug addiction.168
94501114Naloxone Side Effectstachycardia HTN hypotension nausea vomiting tremor withdrawal sx diaphoresis pulmonary edema irritability (peds pts)169
94501115Nicardipine ClassCalcium Channel Blockers170
94501116Nicardipine Trade NameCardene171
94501117Nicardipine MOAinhibits calcium ion influx into vascular smooth muscle and myocardium172
94501118Nicardipine Intended ActionNicardipine is used to treat hypertension (high blood pressure) and angina (chest pain).173
94501119Nicardipine Side Effectsheadache peripheral edema dizziness flushing asthenia angina hypotension nausea/vomiting tachycardia palpitations174
94501123Nitroglycerin ClassNitrates: Vasodilators175
94501124Nitroglycerin Trade NameNitroStat, NitroMyst, Nitrolingual176
94501133Nitroglycerin MOAstimulates cGMP production, resulting in vascular smooth muscle relaxation177
94501135Nitroglycerin Intended ActionNitroglycerin is used to treat or prevent attacks of chest pain (angina).178
94501136Nitroglycerin Side Effectsheadache lightheadedness dizziness flushing hypotension, orthostatic reflex tachycardia edema burning oral sensation (SL use) tingling oral sensation (SL use)179
94501137Nitroprusside ClassNitrates: Vasodilators180
94501140Nitroprusside Trade NameNitropress181
94501179Nitroprusside MOAdirectly dilates peripheral vessels182
94501180Nitroprusside Intended ActionNitroprusside is used to treat congestive heart failure and life-threatening high blood pressure (hypertension). Nitroprusside is also used to keep blood pressure low during a surgery.183
94501188Nitroprusside Side Effectsnausea dizziness restlessness abdominal pain headache diaphoresis reflex tachycardia muscle twitching acidosis ileus bradycardia Cr elevated flushing rash184
94501193Norepinephrine ClassInotropes/Pressors185
94502129Norepinephrine Trade NameLevophed186
94502130Norepinephrine MOAstimulates alpha and beta-1 adrenergic receptors; produces inotropic and vasopressor effects187
94502131Norepinephrine Intended ActionNorepinephrine is used to treat life-threatening low blood pressure (hypotension) that can occur with certain medical conditions or surgical procedures. This medication is often used during CPR (cardio-pulmonary resuscitation).188
94502268Norepinephrine Side Effectsheadache anxiety bradycardia dyspnea189
94502371Ondansetron ClassN/V190
94502375Ondansetron Trade NameZofran191
94502376Ondansetron MOAselectively antagonizes serotonin 5-HT3 receptors192
94502378Ondansetron Intended ActionOndansetron is used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancer (chemotherapy or radiation).193
94502379Ondansetron Side Effectsheadache constipation fatigue diarrhea hypoxia fever urinary retention dizziness agitation pruritus194
94502381Pantoprazole ClassProton Pump Inhibitors195
94502383Pantoprazole Trade NameProtonix196
94502557Pantoprazole MOAinhibits gastric parietal cell hydrogen-potassium ATPase (proton pump inhibitor)197
94503171Pantoprazole Intended ActionPantoprazole is used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome.198
94503329Pantoprazole Side Effectsheadache diarrhea thrombophlebitis (IV use) abdominal pain nausea/vomiting URI sx (peds pts) fever (peds pts) rash (peds pts) dizziness flatulence arthralgia ALT, AST elevated199
94503333Phenylephrine ClassDecongestants200
94503334Phenylephrine Trade NameSudafed201
94503337Phenylephrine MOAstimulates smooth muscle alpha adrenergic receptors, producing vasoconstriction and reducing nasal congestion (sympathomimetic)202
94503338Phenylephrine Intended ActionUsed as a decongestant and as a vasopressor in patients with severe hypotension/shock.203
94503339Phenylephrine Side Effectsinsomnia nausea headache dizziness CNS stimulation anxiety palpitations reflex bradycardia BP elevated tremor urinary retention204
94503340Pentobarbital ClassAnxiolytics, Sedation205
94503412Pentobarbital Trade NameNembutal206
94503549Pentobarbital MOAalters sensory cortex, cerebellar, and motor activities; produces sedation, hypnosis, and anesthesia (barbiturate)207
94503550Pentobarbital Intended ActionPentobarbital is used short-term to treat insomnia. Pentobarbital is also used as an emergency treatment for seizures, and to cause you to fall asleep for surgery.208
94503558Pentobarbital Side Effectssomnolence agitation confusion hyperkinesia ataxia CNS depression hallucinations dizziness apnea bradycardia hypotension syncope nausea vomiting constipation headache209
94503626Phenytoin ClassSeizure Disorders210
94503629Phenytoin Trade NameDilantin211
94503638Phenytoin MOAmodulates neuronal voltage-dependent sodium and calcium channels212
94503639Phenytoin Intended ActionPhenytoin is used to control seizures. Phenytoin does not treat all types of seizures, and your doctor will determine if it is the right medication for you.213
94503640Phenytoin Side Effectsnausea vomiting rash nystagmus ataxia slurred speech dizziness confusion paresthesia blurred vision somnolence constipation headache insomnia gingival hyperplasia taste changes tremor lymphadenopathy coarse facies hyperglycemia osteomalacia phlebitis (IV use) Peyronie dz214
94504010Piperacillin-tazobactam ClassExtended-Spectrum Penicillins215
94504150Piperacillin-tazobactam Trade NameZosyn216
94504151Piperacillin-tazobactam MOAbactericidal; piperacillin inhibits cell wall mucopeptide synthesis; tazobactam inhibits beta-lactamases, added for synergistic effect217
94504152Piperacillin-tazobactam Intended ActionThe combination of piperacillin and tazobactam is used to treat many different infections caused by bacteria, such as urinary tract infections, bone and joint infections, severe vaginal infections, stomach infections, skin infections, and pneumonia.218
94504291Piperacillin-tazobactam Side Effectsdiarrhea headache constipation nausea insomnia rash vomiting dyspepsia pruritus fever agitation electrolyte abnormalities LFTs elevated219
94504294Propofol ClassSedation, Anesthetics220
94504295Propofol Trade NameDiprivan221
94504299Propofol MOAinduces hypnosis222
94504742Propofol Intended ActionPropofol is used to help you relax before and during general anesthesia for surgery or other medical procedure. Propofol is also used in critically ill patients who require a breathing tube connected to a ventilator (a machine that moves air in and out of the lungs when a person cannot breathe on their own).223
94504743Propofol Side Effectsinjection site rxn hypotension involuntary muscle movements resp. acidosis during weaning hyperlipidemia rash pruritus224
94504744Succinylcholine ClassNeuromuscular Blockers225
94504746Succinylcholine Trade NameAnectine226
94504749Succinylcholine MOAstimulates motor endplate acetylcholine receptors (depolarizing neuromuscular blocker)227
94504753Succinylcholine Intended ActionRelaxes your muscles during surgery or intubation (having a breathing tube put into your throat).228
94504754Succinylcholine Side Effectsmyalgia, postop muscle fasciculation jaw rigidity IOP elevated HTN hypotension bradycardia tachycardia sialorrhea rash229
94504755Tobramycin Sulfate ClassAminoglycosides230
94504757Tobramycin Sulfate Trade NameNebcin231
94505044Tobramycin Sulfate MOAbactericidal; binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis232
94505045Tobramycin Sulfate Intended ActionTobramycin injection is used to treat bacterial infections of the skin, heart, stomach, brain and spinal cord, respiratory system, and urinary tract. It is also used in the treatment of cystic fibrosis. Tobramycin injection is sometimes used together with other antibiotics.233
94505046Tobramycin Sulfate Side EffectsBUN, Cr elevated dizziness vertigo tinnitus hearing loss injection site rxn234
94505047Vancomycin ClassOther antibacterials235
94505048Vancomycin Trade NameVancocin236
94505049Vancomycin MOAbactericidal; inhibits cell wall synthesis; inhibits RNA synthesis237
94505050Vancomycin Intended ActionVancomycin is used to treat infections of the intestines that cause colitis (inflammation of the large intestine).238
94505146Vancomycin Side Effectsred-man syndrome (rapid IV use) hypotension (rapid IV use) fever nausea rigors eosinophilia rash urticaria phlebitis tinnitus dizziness/vertigo BUN, Cr elevated vomiting (PO use) flatulence (PO use)239
94505147Vasopressin ClassDiabetes Insipidus, ACLS240
94505428Vasopressin Trade NamePitressin241
94505429Vasopressin MOAacts like ADH; directly stimulates smooth muscle V1 receptors, resulting in vasoconstriction242
94505430Vasopressin Intended ActionVasopressin helps prevent the loss of water from the body by reducing urine output and helping the kidneys reabsorb water in the body. Vasopressin also raises blood pressure by constricting (narrowing) blood vessels.243
94505576Vasopressin Side Effectsabdominal cramps nausea diaphoresis perioral pallor tremor headache flatulence vertigo vomiting diarrhea uterine cramps rash fever urticaria244
94505577Vecuronium ClassNeuromuscular Blockers245
94505578Vecuronium Trade NameNorcuron246
94505579Vecuronium MOAantagonizes motor endplate acetylcholine receptors (non-depolarizing neuromuscular blocker)247
94505581Vecuronium Intended ActionVecuronium is given before general anesthesia in preparing you for surgery. Vecuronium helps keep your body still during surgery. It also relaxes your throat so a breathing tube can be more easily inserted before the surgery.248
94505582Vecuronium Side Effectsmuscle weakness249
945055833% Sodium Chloride ClassHydration250
945055843% Sodium Chloride Trade NameHypertonic Saline251
945055853% Sodium Chloride MOAParticle Osmosis252
945055863% Sodium Chloride Intended ActionPush fluids into the intravascular space from the interstitial space.253
945055873% Sodium Chloride Side Effectsfebrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.254

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