AP Notes, Outlines, Study Guides, Vocabulary, Practice Exams and more!

DNA Structure and the Central Dogma (AP Bio) Flashcards

Terms : Hide Images
1992065315DNAA biological molecule consisting of a phosphorus back bone connected to a 5-carbon sugar and a nitrogenous base; has complementary, anti-parallel strands which form a double-helix that are held together by hydrogen bonding between base pairs; stores genetic information;0
1992238713PurinesNitrogenous bases (adenine and guanine) that have two carbon rings1
1992238714PyramidinesNitrogenous bases (thymine, cytosine, and uracil) that have one carbon ring2
1992238715Anti-ParallelThe direction the complementary strands of DNA run, so that the 5' end is opposite the 3' end3
1992238716Double-HelixThe shape that the complementary strands of DNA form4
1992238717NucleotideThe monomer of DNA consisting of a nitrogenous base of phosphate group bonded to a ribose sugar5
1992238718NucleosidesDNA nucleotide bases with three phosphate groups attached6
1992238719Phosphodiester BondsThe bonds formed between the hydroxide group of the sugar on one nucleotide and the phosphate group of another; runs in the 5' -> 3' direction7
1992238720Base Pairing RulesA:T:U (in RNA); G:C > "everything happens at grand central station"8
1992238721Semi-Conservative ReplicationThe process by which DNA replicates, allowing each strand to serve as a template for a complementary daughter strand which, with the template parent strand, then becomes the new DNA strand9
1992238722Origin of ReplicationThe site where DNA replication begins; prokaryotes only have one of these, but eukaryotes have many10
1992238723Replication BubbleThe shape that forms during replication while parts of the DNA strand are fully synthesized while others have yet to be seperated11
1992238724Replication ForkThe shape that forms during replication where the DNA is split and a majority of enzymatic activity occurs12
1992238725Leading StrandThe complementary strand which is synthesized continuously13
1992238726Lagging StrandThe complementary strand which is synthesized discontinuously14
1992238727Okazaki FragmentsThe short fragments of synthesized DNA that are characteristic of the lagging strand during replication15
1992238728HelicaseA replication enzyme that helps to unwind part of the DNA helix to allow replication to occur16
1992238729Single-Stranded Binding ProteinsProteins that bind to the unwound DNA during replication to help stabilize it and hold it open17
1992238730PrimaseA replication enzyme that lays down a RNA primer during replication to allow for the replication of a segment of DNA by DNA Polymerase III18
1992238731DNA Polymerase IIIA replication enzyme that synthesizes the building of the complementary strand of DNA from the 5' to the 3' direction by breaking the phosphate bonds of nucleosides, thus converting them into joined nucleotides19
1992238732DNA Polymerase IA replication enzyme that replaces RNA primers with nucleotides and "proof-reads" the DNA to catch some mistakes made by DNA Polymerase III20
1992238733LigaseA replication enzyme that seals the "nicks" left in the phosphorus backbone21
1992570427Chromosome ErosionThe gradual shortening of chromosomes due to the loss of bases at the 5' end when the RNA primer is removed22
1992238734TelomeresRepeating, non-coding protective sequences at the end of chromosome to prevent chromosome erosion from affecting vital genes23
1992238735TelomeraseAn enzyme that extends telomeres by replicating from the 3' to 5' direction24
1992286667Central DogmaThe name for describing the flow of information in a cell; DNA -> RNA -> Proteins -> Traits25
1992286668TranscriptionThe "translation" of DNA language to RNA language where a strand of mRNA (the coding strand) is made complementary to a strand of DNA (the template strand)26
1992286669RNA PolymeraseA transcription enzyme that recognizes a sequence and synthesizes a specific kind of RNA from the 5' to 3' end27
1992286670Promoter RegionA binding site before the beginning of a gene (often marked by a 'TATA' box in eukaryotes) which allows RNA polymerase and transcription factors to bind28
1992286671Enhancer RegionA binding site far "upstream" from the gene being expressed which increases the rate of transcription29
1992286672Initiation ComplexThe condition when transcription factors bind to the promoter region which triggers the binding of RNA polymerase to the DNA30
1992286673ExonsExpressed DNA sections31
1992286674Introns"Junk" DNA sequences found in between expressed sections32
1992286675mRNA SplicingA post-transcriptional processing where introns are removed33
1992286676Primary TranscriptThe original mRNA molecule produced, composed of introns and exons34
1992286677Mature mRNAThe mRNA molecule after mRNA splicing has occurred, composed only of exons35
1992286678snRNPs"Small nuclear ribonuclear proteins"; proteins that help to preform mRNA splicing36
1992286679SpliceosomeSeveral snRNP that recognize sequences and "cut" the primary transcript during mRNA splicing37
1992286680Alternative SplicingThe condition where different mature mRNA transcripts are produced from the same gene due to different sequences being treated as exons38
19922866815' GTP CapA post-transcriptional processing where a guanine nucleoside is added to the 5' end of a mature mRNA transcript to protect the end of the molecule39
1992286682Poly-A TailA post-transcriptional processing where multiple adenine nucleotides (20-250 pairs) are added to the 3' end of a mature mRNA transcript to protect the end of the molecule40
1992286683TranslationThe "translation" of mRNA language to amino-acid language where a strand of mRNA codes for a polypeptide41
1992303531CodonA division of mRNA into three base pair segments for translation into a particular amino acid42
1992303532AUGThe start codon which begins protein replication; also codes for methionine (Met)43
1992303533tRNA"Transfer RNA"; RNA with a "clover leaf" structure with an anti-codon on the "clover leaf" end and an particular amino acid attached to the 3' end44
1992303534mRNA"Messenger RNA"; RNA that codes for the construction of proteins that is synthesized in the nucleus45
1992303535RibsomesAn organelle composed of proteins and rRNA that synthesizes the production of proteins; composed of a large and small sub-unit that only come together when translating an mRNA transcript46
1992303536rRNA"Ribosomal RNA"; RNA that helps to construct ribsomes47
1992303537A Site"Aminoacyl-tRNA site"; the site of a ribosome that holds the tRNA carrying the next amino acid to be added to a polypeptide48
1992303538P Site"Peptidyl-tRNA site"; the site of a ribosome that holds tRNA carrying the growing polypeptide chain49
1992303539E Site"Exit site"; the site of a ribosome from where the empty tRNA exits the ribsome50
1992303540InitiationThe process of translation during which mRNA, ribosomal sub-units, and an initiator tRNA are brought together51
1992303541ElongationThe process of translation during which amino acids are added to a growing polypeptide based on codon sequences52
1992303542TerminationThe process of translation during which an end codon is called for by the mRNA transcript and translation stops53

Need Help?

We hope your visit has been a productive one. If you're having any problems, or would like to give some feedback, we'd love to hear from you.

For general help, questions, and suggestions, try our dedicated support forums.

If you need to contact the Course-Notes.Org web experience team, please use our contact form.

Need Notes?

While we strive to provide the most comprehensive notes for as many high school textbooks as possible, there are certainly going to be some that we miss. Drop us a note and let us know which textbooks you need. Be sure to include which edition of the textbook you are using! If we see enough demand, we'll do whatever we can to get those notes up on the site for you!