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DNA Synthesis and Central Dogma Flashcards

review material, concepts, and vocabulary on the central dogma theory of molecular biology, dna synthesis and repair

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100998772exonsexpressed sequence of DNA; codes for a protein0
100998773intronssequence of DNA that is not involved in coding for a protein1
100998774RNA splicingprocess by which the introns are removed from RNA transcripts and the remaining exons are joined together2
100998775template strandThe DNA strand that provides the template for ordering the sequence of nucleotides in an RNA transcript.3
100998776coding strandthe strand of DNA that is not used for transcription and is identical in sequence to mRNA, except it contains uracil instead of thymine4
100998777TATA boxA DNA sequence in eukaryotic promoters crucial in forming the transcription initiation complex5
100998778primary transcriptAn initial RNA transcript; also called pre-mRNA when transcribed from a protein-coding gene.6
100998779spliceosomeA complex assembly that interacts with the ends of an RNA intron in splicing RNA, releasing the intron and joining the two adjacent exons.7
100998780RNA Polymerasean enzyme that pries the 2 strands of DNA apart and hooks together the RNA nucleotides as they base pair along the DNA template8
100998781mRNAtype of RNA that carries instructions from DNA in the nucleus to the ribosome9
100998782tRNAshort-chain RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according10
100998783rRNAThe most abundant type of RNA, which together with proteins froms the structure of ribosomes.11
100998784transcriptionthe organic process whereby the DNA sequence in a gene is copied into mRNA12
100998785translationthe process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm13
100998786AUGStart Codon14
100998787End Codonuaa uag uga15
100998788codona specific sequence of three adjacent bases on a strand of DNA or RNA that provides genetic code information for a particular amino acid16
100998789mutationpermanent change in an organism's DNA. it is a modification in a cell's information archive (change in its genotype). this creates new alleles.17
100998790promotersRegion of DNA that indicates to an enzyme where to bind to make RNA18
100998791core enzymeenzyme that contains the active site for catalysis and other required proteins19
100998792basal transcription factorsGeneral term or proteins, present in all cell types, that bind to eukaryotic promoters and help initiate transcription20
100998793poly(A) tailAfter an mRNA is transcribed from a gene, the cell adds a stretch of adenine nucleotides (typically 100-250) to its 3' end.21
100998794translocationprocess in which mRNA is ratcheted through the ribosome by elongation factors. The tRNA attached to the polypeptide chain moves into the P site. A site empty.22

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