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Hole's Anatomy and Physiology: Chapter 9: Muscles Flashcards

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5023744653Three types of muscle tissues- skeletal muscle - cardiac muscle - smooth muscle0
5023744654Skeletal muscle- usually attached to bone - voluntary - somatic - striated - multiple nuclei1
5023744655somaticwidely distributed2
5023744656Cardiac muscle- wall of heart - involuntary - autonomic - striated - single nucleus - inter-collated disc3
5023744657Smooth muscle- walls of most viscera, blood vessels, and skin - autonomic - not striated - single nucleus - spindle shaped4
5023744658Fasciaconnective tissue surrounding each muscle5
5023744659Tendon- cord-like connective tissue - collegan fibers intertwine with periosteum on bone6
5023744660Aponeuroses- broad, fibrous sheet of connective tissue - may attach to bone or the coverings of adjacent muscles7
5023744661Muscle coverings- epimysium - perimysium - endomysium8
5023744662Epimysiumthin layer of connective tissue that closely surrounds a skeletal muscle9
5023744663Perimysiumsurrounds fascicles within muscles10
5023744664Endomysiumsurrounds muscle fibers (cells) within fascicle11
5023744665Skeletal muscle fibera single muscle cell12
5023744666Sarcolemmamuscle cell membrane13
5023744667Sarcoplasma- cytoplasma14
5023744668Myofibrils- play a major role in muscle contraction - long, parallel structures composed of overlapping protein filaments15
5023744669Myosinthick protein filament16
5023744670Actinthin protein filament17
5023744671Myofibrils structure- produce striations - form a repeating pattern of units called sarcomeres18
5023744672Sarcomeresthe functional unit of muscle contraction19
5023744673Striation patternmade by arrangements of myofilaments in myofibrils20
5023744674I bandonly thin actin filaments (light)21
5023744675A bandthick and thin - myosin and actin (dark)22
5023744676H zonearea with only thick myosin filaments23
5023744677Z linein the center of I bands (where actin is attached)24
5023744678M linethickening in A band (where myosin filament is anchored)25
5023744679A sarcomere extendsfrom one Z line to the next26
5023744680Thick filaments (myosin)- myosin molecules - twisted protein strands called heads27
5023744681Thin filaments (actin)- double strand of actin - troponin - tropomyosin28
5023744682Double strand of actineach molecule has a binding site for the myosin head29
5023744683titinelastic myofilament - myosin filaments are attached to z line by this large protein30
5023744684Troponinattached to actin31
5023744685Tropomyosinlong rod-like, lie in grooves on the actin helix32
5023744686Sarcoplasmic reticulumnetwork of membranous channels that surround the myofibril (= endoplasmic reticulum of other cells)33
5023744687Muscle contraction- movement within the myofibrils - the actin and myosin filaments slide past one another - shortening the sarcomeres - muscles fibers shortens34
5023744688Neuronsconduct action potentials (impluses) along axons to target organs35
5023744689Synapseneuromuscular junction / myoneural junction - site where a motor neuron axon and muscle fiber meet36
5023744690neurotransmitterscross the synaptic cleft and bind to receptors on the motor end plate of the muscle cell37
5023744691Parts of a synapse- motor neuron - motor end plate - synaptic cleft - synaptic vesicles - neurotransmitters38
5023744692Motor neurons- cause a reaction - transmit impulses to effector39
5023744693Motor end platearea of muscle cell where neuron and muscle meet (indention)40
5023744694Synaptic cleftspace between the neuron and the muscle fiber41
5023744695Synaptic vesicles- contain neurotransmitters - located at the end of the axon42
5023744696Axon terminalend of axon43
5023744697acetylcholine (ACh)the neurotransmitter that motor neurons use to control skeletal muscle contraction44
5023744698ACh (Acetylcoline)_______ generates a muscle impulse which reaches the SR and triggers release of calcium ions into sarcoplasm of muscle fiber which leads to muscle contraction45
5023744699Calciumbinds to troponin to change its shape46
5023744700Troponinpulls the tropomyosin off the binding sites - exposing binding sites on actin47
5023744701sliding filament modelwhen sarcomeres shorten, thick and thin filaments slide past one another - H zones and I bands narrow - Z lines move closer together48
5023744702cross bridge cyclingmyosin head attaches to actin binding site - pulls thin filament - ADP and phosphate released from myosin - linkage between actin and myosin break - ATP splits - goes back to original position49
5023744703Acetylcholinesteraserapidly decomposes ACh remaining in the synapse - stopping muscle impulse50
5023744704Relaxation- muscle impulse stops - calcium moves back into sarcoplasmic reticulum (SR) - myosin and actin binding prevented51
5023744705Energy sources for contraction- creatine phosphate - cellular respiration52
5023744706Creatine phosphate- stores energy that quickly converts to ADP and ATP - stored in cells53
5023744707Cellular respiration - anerobic- glycolysis - occurs in cytoplasm - produces little ATP (2)54
5023744708Cellular respiration - aerobic- citric acid cycle - electron transport system - occurs in the mitochondria - produces most ATP - myoglobin stores extra oxygen55
5023744709myoglobinmolecule that stores oxygen until we need it - give red color to muscles56
5023744710oxygen debtamount of oxygen needed by liver cells to use the accumulated lactic acid to produce glucose and to restore muscle ATP and creatine phosphate concentrations57
5023744711muscle fatigueinability to contract muscle - decreased blood flow - Ion imbalances across the sarcolemma - accumulation of lactic acid58
5023744712crampsustained, involuntary muscle contraction59
5023744713threshold stimulusminimal strength required to cause contraction60
5023744714twitchthe contractile response of a single muscle fiber to a single impulse61
5023744715latent periodbrief delay between the time of stimulation and the beginning of contraction (2 milliseconds)62
5023744716myogram of a single muscle twitch- latent period - period of contraction - period of relaxation63
5023744717refractory periodsmall time at the end of muscle twitch when muscle can not be stimulated again64
5023744718all-or-none response- if a muscle fiber is going to contract it will contract completely65
5023744719overly shortened muscle- length-tension relationship not optimal, no where to go66
5023744720overly stretched muscle- length-tension relationship not optimal, not much strength67
5023744721summationprocess by which individual twitches combine - produces sustained contractions - can lead to tetanic contractions68
5023744722tetanicsustained contraction (think - lock jaw)69
5023744723motor unitmotor neuron and the muscle fibers it controls70
5023744724recruitmentincrease number of motor units activated71
5023744725more precise movementsproduced with fewer muscle fibers within a motor unit72
5023744726smaller motor units- smaller diameter axons - recruited first73
5023744727larger motor units- larger diameter axons - recruited as intensity of stimulation increase74
5023744728sustained contractionsallow muscle to produce smooth movements75
5023744729muscle tonecontinuous state of partial contraction76
5023744730slow-twitch muscle fibers (Type I)big muscle groups / red fibers - produce ATP oxidatively - slow to fatigue - most myoglobin - good blood supply77
5023744731fast-twitch glycolytic fibers (Type IIb)white fibers / found in hands and eyes - less myoglobin - poorer blood supply - fewer mitochondria = reduced respiratory capacity - more SR - susceptible to fatigue78
5023744732fast-twitch fatigue-resistant fibers (Type IIa)intermediate fibers / pink to red in color - produce ATP oxidatively - intermediate amount of myoglobin - resistant to fatigue - distributed widely throughout body79
5023744733smooth muscle- shorter muscle fibers than skeletal - single, centrally located nucleus - elongated with tapering ends - lack striations - lack transverse tubules - sarcoplasmic reticula not well developed80
5023744734smooth muscle locationwalls of hollow organs81
5023744735major types of smooth muscle (2)- multi-unit - visceral82
5023744736multi-unit smooth musclefound in iris of eye and walls of blood vessels - less organized - function as separate units83
5023744737visceral smooth musclefound in the walls of hollow organs - single-unit smooth muscle - sheets of muscle fibers - held together by gap junctions - exhibit rhythmicity and peristalsis84
5023744738rhythmicitya pattern of spontaneous repeated contractions85
5023744739peristalsiswave-like motion - alternate contractions and relaxations of the longitudinal and circular muscles86
5023744740smooth muscle contraction- calmodulin protein instead of troponin - two neurotransmitters - affected by hormones - stretching can trigger contraction - resistant to fatigue - can change length without changing tautness87
5023744741smooth muscle neurotransmitters- acetlycholine - norepinephrine88
5023744742norepinephrine- associated with fight or flight - opens blood vessels to make muscles move faster - stops digestion89
5023744743cardiac muscleonly in the heart - striated - muscle fibers joined together by intercalated discs - fibers branch - network of fibers contracts as a unit (syncytium)90
5023744744syncytiumnetwork of fibers contracting as a unit (all-or-none manner)91
5023744745leversBones and muscles interact as simple mechanical devises called ___________.92
5023744746rigid barbones93
5023744747fulcrumjoint - point on which the bar moves94
5023744748objectweight - moved against resistance95
5023744749forcemuscles - supplies energy for movement96
5023744750originimmovable end of a muscle97
5023744751insertionmovable end of a muscle98
5023744752prime mover (agonist)primarily responsible for movement99
5023744753synergistassist prime mover100
5023744754antagonistcontraction causes movement in the opposite direction of the prime mover101

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