Columbia P&S 2014
Purine synthesis inhibitor | ||
Calcineurin inhibitor | ||
calcineurin inhibitor | ||
mTor inhibitor | ||
Nephrotoxicity, CV disease. | ||
Block mTor, thereby preventing transmission of IL-2 proliferative signal in TC. | ||
Prevent IL-2 secretion, the major proliferative signal | ||
Calcineurin inhibitors (cyclosporine, tacrolimus) | ||
Sevelamer, CaCO3, Calcium acetate | ||
Autosomal dominant | ||
VDRA (vitamin d receptor activators) | ||
Diffusion | ||
Convection / Ultrafiltration | ||
Erythropoietin (epoetin alpha) | ||
Phosphate binders and vitamin B complex vitamins. |