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Microbiology A Systems Approach: 8. Microbial Metabolism: The Chemical Crossroads of Life Flashcards

Microbiology A Systems Approach Ed 3
Marjorie Kelly Cowan

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896689531Active Site (Catalytic Site)Site where a specific substrate binds to enzyme, activating its function ☐ Works like a key entering a lock0
896689532Aerobic RespirationSeries of reactions that convert glucose to carbon dioxide and allows the cell to recover significant ATP ☐ Requires oxygen1
896689533Alcoholic FermentationOccurs in yeast or bacteria that convert pyruvic acid to ethanol ☐ Produce ethanol and carbon dioxide2
896689534Amination...3
896689535AminotransferaseTransfers amino group4
896689536AmphibolismProperty of a system to integrate catabolic and anabolic pathways to improve cellular efficiency ☐ Usu. during Glycolysis and Krebs Cycle5
896689537Anabolism (Biosynthesis)Any process that results in synthesis of cell molecules and structures ☐ Endergonic6
896689538Anaerobic RespirationDoes not use molecular oxygen as the final electron acceptor7
896689539Anoxygenic PhotosynthesisForm of photosynthesis that does not produce oxygen ☐ Doesn't use oxygen as electron donor ☐ Found in four different bacterial groups: purple bacteria, green sulfur bacteria, green non-sulfur bacteria, and heliobacteria8
896689540ApoenzymeProtein portion of Conjugated Enzyme (Holoenzyme)9
896689541ATP...10
896689542Beta oxidation...11
896689543Carbon fixation...12
896689544CatabolismThe breakdown of bonds of larger molecules into smaller molecules ☐ Exergonic13
896689545Catalysts...14
896689546ChemiosmosisA process for synthesizing ATP using the energy of an electrochemical gradient and the ATP synthase enzyme15
896689547Chloroplast...16
896689548Coenzymes...17
896689549CofactorNon-protein portion of Conjugated Enzyme (Holoenzyme) ☐ Organic Molecule (coenzyme) or Inorganic Molecule (metal ions)18
896689550Cofactors...19
896689551Competitive InhibitionThe cell supplies a molecule that resembles the enzyme's normal substrate, which then occupies and blocks the active site20
896689552Conjugated Enzyme (Holoenzyme)Consists of protein (Apoenzyme) and non-protein (cofactor) molecules21
896689553Constitutive EnzymeAlways present and in relatively constant amounts22
896689554CytochromesCarriers in ETC23
896689555DecarboxylaseRemoves carbon dioxide24
896689556Dehydration ReactionUses ATP ☐ Links monomers ☐ Forms water25
896689557DehydrogenaseTransfers hydrogen from one substrate to another26
896689558Dehydrogenation...27
896689559DenaturationThe weak bonds that maintain the native shape of the Apoenzyme are broken ☐ High temp, pH ☐ Loses shape and function28
896689560DentrificationWhen enzymes can further reduce nitrite to nitric oxide, nitrous oxide, and nitrogen gas29
896689561Electron CarrierRepeatedly accepts and releases electrons and hydrogens ☐ Most common is NAD30
896689562Electron Transport ChainA series of proteins in which the high-energy electrons from the Krebs cycle are used to convert ADP into ATP31
896689563EndergonicReaction requiring input of energy to proceed32
896689564EndergonicRequires input of energy to start reaction33
896689565EndoenzymeBreaks down molecules inside of cell34
896689566Energy of ActivationThe amount of energy which must be overcome for a reaction to proceed35
896689567Energy...36
896689568Enzyme InductionIncreases enzyme expression37
896689569Enzyme RepressionDecreases enzyme expression38
896689570Enzymes...39
896689571ETS...40
896689572ExergonicEnergy is released during reaction41
896689573ExergonicReaction which releases energy42
896689574ExoenzymeBreaks down molecules outside of cell43
896689575FAD...44
896689576Ferment...45
896689577FermentationUses only glycolysis to incompletely oxidize glucose ☐ Small energy production46
896689578Final electron acceptor...47
896689579GluconeogenesisGeneration of glucose from non-sugar carbon substrates like pyruvate, lactate, glycerol, and amino acids The vast majority takes place in the liver and, to a smaller extent, in the cortex of kidney. This process occurs during periods of fasting, starvation, or intense exercise and is highly endergonic48
896689580GlycolysisFirst step in releasing the energy of glucose, in which a molecule of glucose is broken into two molecules of pyruvic acid49
896689581Holoenzyme...50
896689582HydrolaseUses water to break bonds51
896689583Hydrolysis ReactionSeparates monomers ☐ Uses water to break it52
896689584Induced enzymes...53
896689585Krebs CycleStage of cellular respiration, in which pyruvic acid is broken down into carbon dioxide in a series of energy-extracting reactions54
896689586LabileWhen enzymes are subjected to changes in normal conditions and become unstable55
896689587LigaseForms bonds using ATP56
896689588Light Dependent ReactionReactions of photosynthesis that use energy from light to produce ATP and NADPH57
896689589Light Independent ReactionSet of reactions in photosynthesis that do not require light ☐ Energy from ATP and NADPH is used to build high-energy compounds such as sugar ☐ Also called the Calvin Cycle58
896689590Light ReactionThe first stage of photosynthesis during which energy from light is used for the production of ATP ☐ Occurs in eukaryotic thylakoid, or bacterial cell membrane59
896689591Metabolic PathwayA series of chemical reactions that either builds a complex molecule (anabolic pathway) or breaks down a complex molecule into simpler compounds (catabolic pathway)60
896689592MetabolismAll the chemical and physical workings of the cell61
896689593Metabolites...62
896689594Metallic cofactors...63
896689595MethyltransferaseTransfer methane64
896689596NAD...65
896689597Negative feedback...66
896689598Noncompetitive InhibitionThe enzyme has two binding sites, the active and regulatory site ☐ A molecule binds to the secondary regulatory site and inhibits the functioning of the enzyme ☐ A negative feedback mechanism67
896689599Oxidation-Reduction ReactionsLoses electrons (oxidized) or gains electrons (reduced)68
896689600Oxidized...69
896689601Oxygenic PhotosynthesisGenerate oxygen as a by product after splitting water molecules to obtain electrons70
896689602PhosphorylateAdd phosphate group ☐ energetic bond71
896689603PhosphotransferaseTransfers phosphate group (energy)72
896689604PhotolysisA reaction taking place in the thylakoid membranes of a chloroplast during light-dependent reactions where two molecules of water are split to form oxygen, hydrogen ions, and electrons73
896689605PhotophosphorylationProcess where light reactions generate ATP using chemiosmosis to power the addition of a phosphate group to ADP74
896689606Photosynthesis...75
896689607Pyruvic AcidThe three-carbon compound that is produced during glycolysis and needed for both the aerobic and anaerobic pathways of cellular respiration that follow glycolysis76
896689608Redox reactions...77
896689609Reduced...78
896689610Regulated EnzymeProduction is either induced or repressed in response to a change in concentration of the substrate79
896689611Regulatory...80
896689612RibozymeNewly found enzyme made of RNA molecules81
896689613RuBP...82
896689614Simple EnzymeConsists of only protein83
896689615Substrate Level PhosphorylationThe formation of ATP by directly transferring a phosphate group to ADP from an intermediate substrate in catabolism84
896689616Substrate...85
896689617TransaminationAmino acids and carbohydrates are interchanged86
896689618Virulence Factor (Toxin)Exoenzyme secreted by pathogen that helps them avoid host defenses and promote multiplication in tissues87

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