2134286614 | In the nervous system, what is the sensory input to provide information on internal and external environment? | Afferent | 0 | |
2134288128 | In the nervous system, what is the motor portion of the nervous system? | Efferent | 1 | |
2134300097 | What are the 3 components of the autonomic nervous system? | Sympathetic, parasympathetic, and enteric | 2 | |
2134303467 | The SNS is located where? | Thoracolumbar | 3 | |
2134304405 | The PSNS is located where? | Craniosacral | 4 | |
2134321450 | Where does the enteric nervous system receive input from? | SNS, PSNS, and direct sensory input from wall of the gut | 5 | |
2134369830 | What is the neurotransmitter for cholinergic receptors? | AcH | 6 | |
2134371305 | What is the neurotransmitter for adrenergic receptors? | Epi, Dopamine, NE (primary), and co-transmitters (e.g. calcium - if a patient is not affected by increases in neurotransmitters the patient may be low on calcium) | 7 | |
2134393566 | What is the primary neurotransmitter of adrenergic receptors? | NE | 8 | |
2134404205 | *Where are cholinergic fibers located?* | - Pre-ganglionic efferent autonomic fibers - Somatic (non-autonomic) motor fibers to skeletal muscles - Most parasympathetic post-ganglionic fibers - Some sympathetic post-ganglionic fibers | 9 | |
2134480302 | *Where are adrenergic receptors located?* | - Post-ganglionic sympathetic fibers | 10 | |
2134513834 | *What is the rate limiting step to Dopamine?* | The formation of Tyrosine to Dopa | 11 | |
2134522013 | What is given to stop formation of Tyrosine? | Metyrosine | 12 | |
2134526915 | Where does Reserpine stop formation of NE? | Inhibits the vesicular monoamine transporter in the wall of the storage vesicle | 13 | |
2134530193 | What 2 drugs inhibit NET (carries NE back into the cell cytoplasm from the synaptic cleft)? | Cocaine and TCA drugs | 14 | |
2134555132 | What is ergotrophic and what are some physiological effects? | Ergotrophic is sympathetic. Physiologic effects are energy expenditure, fight or flight, cardiac stimulation, increased blood sugar, cutaneous vasoconstriction, and relaxes bronchial smooth muscle. | 15 | |
2134558956 | What is tropotrophic and what are some physiological effects? | Tropotrophic is parasympathetic. Physiologic effects are leading to growth, slowing of the heart, stimulation of digestive activity, and constricts bronchial smooth muscle (e.g. asthma patient will have cough early in the morning because SNS is non-existent) | 16 | |
2134574984 | What is pre-synaptic regulation? | - Can be inhibitory or excitatory - Negative feedback control | 17 | |
2134681579 | What is an example of pre-synaptic regulation? | Alpha 2 receptor on noradrenergic nerve terminals. Activated by NE and alpha 2 agonists. Activation DECREASES release of NE. G-protein mediated effect to inhibit calcium inward movement. | 18 | |
2134693257 | What is post-synaptic regulation? | - Modulation by history of activity Up-regulation: After denervation of tissues. Administration of drugs that deplete transmitter stores. E.g. Reserpine --> Increased sensitivity. BB --> Increased receptors. Withdrawal --> Increased beta activity. Down regulation - Modulation by other temporarily associated events | 19 | |
2134877388 | What are the primary divisions of the ANS? | SNS and PSNS | 20 | |
2134878773 | What are the 2 main neurotransmitters in the ANS? | AcH and NE | 21 | |
2134880360 | What are type of receptors in the ANS? | Cholinergic (AcH) and adrenergic (NE) | 22 | |
2134883325 | What is meant by negative feedback? | Pre-synaptic regulation - Can be inhibitory or excitatory | 23 | |
2134896745 | What is the rate limiting step in the synthesis of catecholamines? | Inhibited Tyrasine | 24 |
P&P Exam 1: Basic & Clinical Pharmacology Flashcards
Primary tabs
Need Help?
We hope your visit has been a productive one. If you're having any problems, or would like to give some feedback, we'd love to hear from you.
For general help, questions, and suggestions, try our dedicated support forums.
If you need to contact the Course-Notes.Org web experience team, please use our contact form.
Need Notes?
While we strive to provide the most comprehensive notes for as many high school textbooks as possible, there are certainly going to be some that we miss. Drop us a note and let us know which textbooks you need. Be sure to include which edition of the textbook you are using! If we see enough demand, we'll do whatever we can to get those notes up on the site for you!