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Qualitative Defects and T & B Deficiency Disorder Flashcards

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4752350514Chronic Granulomatous Diseasedefect in the NADPH oxidase system0
4752350515Myeloperoxidase Deficiencydeficiency in myeloperoxidase which is an important microbicidal agent in normal neutrophils1
4752350516Chediak Higashi Syndromedefect in gene encoding the lysosomal trafficking regulator protein2
4752350517Job's Syndromeneutrophils demonstrate defective chemotaxis but normal ingestion and killing3
4752350518Lazy Leukocyte Syndromedefective chemotactic response by neutrophils4
4752350519Tuftsin Deficiencytuftsin deficiency ehich is a phagocytosis-promoting serum tetrapeptide that is cleaved from an Ig like molecule, leukokinin, in the spleen5
4752350520Leukocyte adhesion deficiencyleukocytes have defects of adhesion to endothelial surfaces and to each other as well as poor chemotactic and phagocytic activities6
4752350521Bruton's AgammaglobulinemiaGenetic defect in long arm of X chromosome resulting in a block in the maturation of pre-B cells into lymphocytes with surface IgM7
4752350522Dysgammaglobulinemiasuggested that an arrest in the development of the B cells in the culprit8
4752350523Selective IgA deficiencydefect in class switching9
4752350524Selective IgA deficiencyMost Common Immunodeficiency Disorder10
4752350525Transient hypogammaglobulinemia of infancyOnset of Ig synthesis11
4752350526Digeorge syndromeabsence or hypoplasia of thymus and parathyroid glands12
4752350527Chronic mucucutaneous candidiasisT cells show an impaired ability to produce macrophage migration inhibiting factor (MIF) in response to candida antigen13
4752350528Bare lymphocyte syndromedeficiency in the expression of class II MHC gene products14
4752350529Severe Combined Immunodeficiency disease (SCID)combined defect in both humoral and cell mediated immunity15
4752350530Nezelof's syndromeThymic dysplasia16
4752350531Wiskott Aldrich Syndrome (WAS)Mutation in WASP gene17
4752350532Ataxia TelangiectasiaResult of specific genetic defect that affects DNA repair and alters the function of organ systems18
4752350533X-Linked lymphoproliferative Disease or Duncan's syndromeMutation in SH2Dta/SAPaa gene resulting in weakening of both humoral and cell mediated immune response19

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