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Urinary System AP2 Flashcards

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10395181775Urinary system Functions?1. regulating body's water volume 2. regulating ion concentrations 3. excreting metabolic wasted and drugs/toxins 4. producing erythropoietin (rbc's) and renin0
10395181776Urinary System Anatomy1. kidneys 2. ureters 3. urinary bladder 4. urethra1
10395181777Kidney has 4 parts1. External Anatomy 2. Internal Anatomy 3. Blood supply 4. Nerve supply2
10395201833External Anatomy of Kidney1. Bean-shaped 2. Renal Hilum 3. Renal Fascia 4. Perirenal Fat capsule 5. Fibrous capsule3
10395201834Bean-shapedprotected by floating ribs4
10395236563Renal Hilumwhere blood vessels and ureters enter/exit5
10395238217Renal Fascialines kidneys; dense CT; holds them in place6
10395239093Perirenal Fat Capsuleadipose, cushions kidneys7
10395239695Fibrous Capsuleouter layer; keeps infections out8
10395241240Internal Anatomy of Kidney1. Renal cortex 2. Renal Medulla 3. Renal Pelvis9
10395244683Renal Cortexouter part of kidney10
10395245286Renal Medulla1. Renal pyramids 2. Renal columns 3. 1 pyramid + columns + cortex= a lobe (8 total)11
10395248687Renal PelvisMajor and minor calyces or calyx12
10395251223Blood supply1. Renal artery splits into segmental arteries, keeps splitting, going towards renal cortex 2. Branches rejoin and leave via renal vein13
10395252334Nerve SupplyRenal Plexus14
10395253543Renal Plexusautonomic nerves, regulates blood flow and urine production.15
10395255540NephronThe structural and function unites of kidneys a) each kidney has over 1 million nephrons16
10395258490Function of Nephron1. filter blood 2. reabsorb some substances if needed, and send what's left (urine) to the renal pelvis17
10395274134Renal Corpuscleits in the cortex 1) Glomerulus 2. Bowman's capsule18
10395277963Glomerulustuft of fenestrated capillaries19
10395278777Bowmans capsulehollow ball, holds glomerulus 1. parietal layer 2. visceral layer 3. fluid (filtrate) filtrate filters out of the capillaries into a capsule 4. only smaller molecules can leave capillaries20
10395282846Parietal layersimple squamous epithelium21
10395283445Visceral layerpodocytes lines glomerular surface22
10395284102Renal Tubule1. proximal convoluted tubule (PCT) 2. Descending and Ascending Loop of Henle 3. Distal convoluted tubule (DCT)23
10395286919Proximal convoluted tubule (PCT)1. carries filtrate from Bowman's capsule 2. simple cuboidal epithelium WITH microvilli24
10395289426Descending and Ascending Loop of Henle1. travels down into renal medulla, back up to cortex 2. Mixture of epithelial types25
10395292390Distal convoluted tubules (DCT)simple cuboidal epithelium WITHOUT microvilli26
103952939182 types of nephrons1. cortical nephrons 2. Juxta medullary nephrons27
10395295049Cortical nephronsshort loops of henle28
10395296394Juxta-medullary nephronsvery long loops, help to concentrate urine29
10395298389Nephrons1. Renal copuscle 2. Renal tubule 3. collecting ducts 4. capillary bed 5. Juxta glomerular Complex (JGC)30
10395301452Collecting ducts1. many DCTs empty into the same collecting duct 2. carries filtrate down through pyramids to renal pelvis31
10395303907Capillary beds1. Glomerulus has an afferent and efferent arteriole a) peritubular capillaries b) Vasa Recta32
10395309469Peritubular capillariescome from efferent aterioles a) wrap PCT and DCT, reabsorb some solutes and most water from the filtrate b) empty into venules33
10395311550vasa rectaalso come from efferent arterioles a) surrounds loops of Henle of juxtamedullary nephrons34
10395314596Glomerulusmakes filtrate (urine) then the peritubular capillaries and vasa recta reabsorb most substances back into circulation35
10395317323Juxtaglomerular comples (JGC)Each nephron's ascending loop of Henle passes by the afferent and efferent arterioles36
103953189203 types of Juxtaglomerular Comples (JGC)1. Macula Densa 2. Granular cells 3. Mesangial Cells37
10395320156Macula DensaCells that detect NaCl left in filtrate in the ascending loop38
10395321775Granular cellssmooth muscle; controls diameter of afferent and efferent arterioles39
10395323700Mesangial cellscarry signals from macula densa to granula cells40
10395325704Urine Formation 1: Glomerular Filtration (GFR) {5 PARTS}1. Filtration Membrane 2. Pressures affecting filtration 3. Regulations of GFR 4. Tubuloglomerular Feedback 5. Renin-angiotensin- aldosteron mechanism41
10395330757Filtration membrane1. Fenestrated glomerular capillary 2. Basement membrane 3. Podocytes42
10395332824Fenestrated glomerular capillarylets out everything except blood cells43
10395333261Basement membraneblocks all but the smallest proteins44
10395333734Podocytesin bownman's capsule 1. cells that make sure large molecules stay in bloo 2. wrap around glomerulus45
10395335301pressures affecting filtration1. Hydrostatic Pressure of blood in glomerulus (HPG) 2. Hydrostatic pressure of filtrate in capsule (HPC) 3. Colloid osmotic pressure in glomerulus (COPG)46
10395340021Hydrostatic pressure of blood in glomerulus (HPG)high blood pressure, forces solutes out (+55 mmHg)47
10395341457Hydrostatic pressure of filtrate in capsule (HPC)pushes back against HPG (-15 mmHg)48
10395341986Colloid osmotic pressure in glomerulus (COPG)proteins in blood pull filtrate back (-30mmHg)49
10395344667Net Filtration PressureHPG - HPC - COPG = Net Filtration Pressure (NFP)50
10395348510Golmerular Filtration (GFR)Net filtration pressure (NFP) determines this51
10395350080Urine FormationGlomerular Filtration determines the rate of urine formation52
10395353092Regulation of GFR:changing glomerular BP a) myogenic mechanism53
10395358167Myogenic Mechanisma) if AA gets stretches from high BP, it will constrict and vice versa b) keeps extreme BP changes from damaging glomerulus54
10395360971Tubuloglomerular Feedback1. Juxtaglomerular complex detects NaCl levels 2. High NaCl ===> vasoconstriction of AA (lower GFR) 3. Low NaCl ===> vasodilation of AA (higher GFR)55
10395367726Renin-angiotension-aldosterone mechanismIndirect; raises systemic BP (and thus GFR)56
103953696114 parts of Renin-angiotension-aldosterone mechanism1. Low BP ==> granular cells release renin 2. Renin activates angiotensin from liver 3. Angiotensin ===> adrenal cortex secretes aldosterone 4. Aldersterone - has 4 parts (next card)57
10395374800Alderstone1. reabsorbs more sodium and thus more water 2. Post. Pituitary releases ADH ==> more water reabsorption in kidneys 3. triggers thirst 4. vasocontrictor58
10395379379Urine Formation 2: Tubular ReabsorptionMost filtrate reabsorbed into peritubular capillaries around the PCT, LoH, DCT, and CD a) most reabsorption happens in PCT b) NA+ reabsorbed by active transports (pumps and ATP)--- Glucose, vitamins, etc tag along (2nd active transport) c) H2O follows Na+ by osmosis d) other ions (Cl, K, Ca), lipid- soluble solutes and urea- diffusion down concentration reabsorption59
10395399523Urine formation 2: Tubular ReabsorptionHormones affecting reabsorption: 1) Antidiuretic Hormone (ADH) 2. Aldosterone 3. Atrial Natriuteic Peptide (ANP) 4. Parathyroid Hormone (PTH)60
10395403782antidiuretic hormone (ADH)its from posterior pituitary a) it reduces urine by increasing water reabsorption in CD61
10395407202Aldosteroneis from adrenal cortex a) it raises BP by reabsorbing Na+ and water in DCT and CD62
10395409869Arial natriuretic peptide (ANP)Its from the heart, a) lowers BP by slowing Na+ and water reabsorption63
10395412303Parathyroid Hormone (PTH)increases absorption of calcium in DCT64
10395415223Urine Formation 3: Tubular SecretionGetting rid of junk that wasn't filtered or was reabsorbed a) drugs, urea, uric acid, K+, H+ b) happens throughout PCT, LoH, DCT, and CD65
10395417519Urine1. clear, pale yellow ( pigment= urochrome) 2. smells like ammonia 3. pH~ 6 4. 95% water 5. Urea, uric acid, creatinine, Na+, K+ a) several other ions and small molecules66
10395424333UretersCarry urine from renal pelvis to urinary bladder67
10395424957Ureters has 3 layers1. Mucosa 2. Muscularis 3. Adventita68
10395426020Mucusawith transitional epithelium69
10395426643Musculariscircular and longitudinal smooth muscle70
10395427729Adventitafibrous CT71
10395428214Urinary Bladder1. very distensible, stores up to ~800 mL 2. same 3 layers (Mucosa, Muscularis, Adventita)72
10395431217Urethra1. drains urine from bladder to outside body 2. internal (involuntary) and External (voluntary) sphincters 3. Males 4. Females73
10395432586urethra in Male1. runs through prostate glands out through penis 2. also carries semen74
10395433248urethra in Female1. short, anterior to vagina, posterior to clitoris 2. Micturation= urination75
10395435136Anurialow urine production76
10395435520Renal Failurekidneys stop working77
10395435529Hemodialysismachine does the kidney's job78
10395436417Renal Calculi(kidney stones), precipitated calcium or uric acid a) treat with surgery or shock wave lithotripsy79
10395438407Urinary tract infectionsbacterial, more common in women80
10395442186Glycosuriaglucose in urine, indicates Diabetes mellitus81
10395443515Proteinuriaproteins in urine, from physical exertion, pregnancy, heart failure, glomerulonephritis82
10395444806Bilirubinurialiver disease83
10395445891Hemoglobinuriatransfusion reaction, anemia84
10395447074HematuriaRBCs in urine, bleeding from stones, infections, cancer and other trauma85
10395448126PyuriaWBCs in urine, UTI86

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