AP Notes, Outlines, Study Guides, Vocabulary, Practice Exams and more!

Wilkins AP Biology DNA Flashcards

Terms : Hide Images
8979625590DNA Replicationthe process by which a DNA molecule is copied; also called DNA synthesis0
8979625591Transformationa change in genotype and phenotype due to the assimilation of external DNA by a cell transforming substance- DNA1
8979625592BacteriophagesViruses that infect bacteria Bacteria eaters2
8979625593Virusinfects a cell and takes over the cell's metabolic machinery3
8979625594Hershey and Chase ExperimentConcluded that phage DNA entered bacterial host cells, but phage proteins did not, so DNA functions as the genetic material4
8979625595Griffith ExperimentThe first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.5
8979625596Chargaff's Lawthe base compostion of DNA varies between species and for each species, the percentages of A and T bases are roughly equal to the percentages of the G and C bases6
8979625597Rosalind Franklinaccomplished X-ray crystallographer that discovered the double helix of DNA7
8979625598Antiparallelsubunits run in opposite directions8
8979625599Nitrogenous bases of DnaA, T, C, G9
8979625600PurinesA and G Nitrogenous bases with two organic rings10
8979625601PyrimidinesC and T Nitrogenous base with a single organic ring11
8979625602Conservative modeltwo parental strands reassociate after acting as templates for new strands thus restoring the parental double helix12
8979625603Semiconservative Modelthe two strands of the parental molecule separate and each functions as a template for synthesis of a new complementary strand- most common13
8979625604Dispersive Modeleach strand of both daughter molecules contains a mixture of old and newly synthesized DNA14
8979625605Origins of Replicationshort stretches of DNA having a specific sequence of nucleotides15
8979625606Replication Forka Y shaped region where the parental strands of DNA are being unwound16
8979625607Helicasesenzymes that untwist the double helix at the replication forks, separating the two parental strands and make them available as template strands17
8979625608Single Strand Binding ProteinsBind to the unpaired DNA strands keeping them from repairing18
8979625609TopoisomeraseThe untwisting of double helix causes tighter twisting and strain ahead of replication fork Relieve this strain by breaking swiveling, and rejoining DNA strands19
8979625610PrimerThe initial nucleotide chain that is produced during DNA synthesis is actually a short stretch of RNA20
8979625611PrimaseSynthesizes the primer Starts a complementary RNA chain from a single RNA nucleotide, adding more RNA nucleotides one at a time, using the parental DNA strand as a template21
8979625612DNA polymerasesEnzyme that catalyze the synthesis of new DNA by adding nucleotides to a preexisting chain22
8979625613Leading strandStrand that continuously adds nucleotides to the new complementary strand as the fork progresses DNA pol III23
8979625614Lagging StrandThe strand that DNA pol III works away from the replication fork Synthesized discontinuosly as a series of segments24
8979625615Okazaki fragmentsSeries of segments that are 1000-2000 nucleotides long25
8979625616DNA Ligasejoins the sugar phosphate backbones of all the Okazaki fragments into a continuous DNA strand26
8979625617DNA pol IIISynthesizes new DNA strands by adding nucleotides to an RNA primer or a pre-existing DNA strand27
8979625618DNA pol IRemoves RNA nucleotides of primer from 5' end and replaces them with DNA nucleotides28
8979625619Mismatch repairOther enzymes remove and replace incorrectly paired nucleotides that have resulted from replication errors29
8979625620NucleaseDNA cutting enzyme that cuts out the damaged parts of the strand and fills the space with nucleotides using the undamaged strand as a template30
8979625621Nucleotide excision repairDNA repair system where teams of enzymes detect and repair the DNA, the nuclease cuts out the damaged DNA and removes it, fills in the missing nucleotides and the DNA ligase seals the free end of the new DNA to the old DNA making the strand complete31
8979625622TelomeresSpecial nucleotide sequences at the ends of chromosomes TTAGGG is repeated between 100-1000 times Prevent the staggered ends of daughter molecule from activitating cell's system for monitoring DNA damage32
8979625623TelomeraseEnzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells and restores the original length and compensating for the shortening that occurs during DNA replication33
8979625624HistonesProteins that are responsible for the first level of DNA packing in chromatin34
8979625625Nucleosomethe basic unit of DNA packing35
8979625626Chromatincomplex of DNA and protein36
8979625627Heterochromatincentromeres and telomeres exist in a highly condensed state with visible irregular clumps making it largely inaccessible37
8979625628Euchromatincentromeres and telomeres exist in a less compacted state that is very accessible38

Need Help?

We hope your visit has been a productive one. If you're having any problems, or would like to give some feedback, we'd love to hear from you.

For general help, questions, and suggestions, try our dedicated support forums.

If you need to contact the Course-Notes.Org web experience team, please use our contact form.

Need Notes?

While we strive to provide the most comprehensive notes for as many high school textbooks as possible, there are certainly going to be some that we miss. Drop us a note and let us know which textbooks you need. Be sure to include which edition of the textbook you are using! If we see enough demand, we'll do whatever we can to get those notes up on the site for you!