the diagnosis that reflects the excessive anterior pituitary gland secretion of ACTH, can be caused by tumor on the adrenal or pituitary gland ( too much corisol, blood glucose rises extra glucose stored as fat in the face, abdomen, back of neck, high blood pressure) | ||
(hyperadrenocorticism) a collection of signs and symptoms caused by an excessive level of cortisol hormone from any cause, symptoms include upper body obesity, facial puffiness (moon-shaped appearance), hyperglycemia, weakness, thin, and easily bruised skin with stria (stretch marks), hypertension, and osteoporosis. | ||
insufficient steriod hormones involving both glucocorticoids and mineralocorticoids. Symptoms: weight loss and hypoglycemia | ||
includes primary adrenal insufficiency (Addison Disease) and secondary hypocortisolism | ||
causes adrenal atrophy and hypofunction and is an organ-specific autoimmune disease Autoimmune destruction of adrenal cortex, associated with auto-immune polyendocrine system (APS), low cortisol, increased ACTH: | ||
Low ACTH levels | ||
Adrenocorticotropic hormone, produced by the anterior pituitary gland that stimulates the adrenal cortex | ||
secreted by the adrenal cortex they help to regulate metabolism of sodium choride and potassium. | ||
These hormones affect ion transport by epithelial cells. Increases the activity of sodium pump of the epithelial cells. Causes sodium retention and K+ and hydrogen loss. | ||
The most potent naturally occurring mineralcorticoid. It is regulated by the renin-angiotension system | ||
adrenal gland overproduces aldosterone (adenoma or hyperplasia) causes an increase in sodium and water retention & potassium excretion in the kidneys. Leads to arterial hypertension.(Conn disease) | ||
Overactivity of the renin-angiotension system. extra-renal cause of adrenal cortex overstimulation | ||
the adrenal cortex secretes these | ||
secretion of this hormone by the adrenal glands is minimal | ||
androgens are converted by peripheral tissues to stronger androgens such as this hormone | ||
Hypersecretion of adrenal androgens and estrogens | ||
the development of female characteristics (loss of facial hair or breast enlargement) in a male because of hormonal disorder of the adrenal cortex | ||
the abnormal development of male sexual characteristics in a female (usually as the result of hormone therapies or adrenal malfunction) | ||
make and secrete catecholamines (epinephrine and norepinephrine) in adrenal medulla | ||
release of catecholamines has been characterized as this type of response | ||
The neurotransmitters dopamine, epinephrine, and norepinephrine, which are active in both the brain and the peripheral sympathetic nervous system., Adrenal glands secerets this to activate various organs that results in a phyiscal stress response. | ||
catecholamines promote hyperglycemia or hypoglycemia? | ||
caused by tumors derived from the chromaffin cells of the adrenal medulla (pheochromocytomas- tumors of the pheochromocytes or chromaffin cells) | ||
adrenal medulla hyperfunction causes this which results in secretion of catecholamines on a continuous or episodic basis. |
Pathophysiology test 3 part II
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