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Ch. 4 Chromosomal Basis of Inheritence Flashcards

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183245967X/Y systemxx = females xy = males mammals, spinach, marijuana
183245968X/O systemxx = females xo = males insects, grasshopers, crickets
183245969Z/W systemzw = females zz = males Birds, fishes, strawberries
183245970Haplo-Diploidy Systemfertilized eggs = female unfertilized eggs = male no sex chromosomes
183245971No Sex Determination SystemMonoecious (hermaphrodite) Both sexes in one organism Plants, snails, earthworms
183245972The Lyon HypothesisHemizygous = M + xy Females = xx = physiological imbalance 1 chromosome tightly condensed for equalization of transcription
183245973How to Determine the Number of Barr BodiesNumber of chromosomes X chromosomes - 1 males = 1x-1 = 0 females = 2x-1=1
183245975Inheritence of X-Linked Dominant TraitsFathers passed to daughters Incontinentia Pigmenti
183245976types of aneuploidy and related syndromesTrisomy 21 - Downes Syndrome Trisomy 12 - Pataos Syndrome Trisomy 18 - Edwards Syndrome Monosomy - Tuners Syndrome XXY - Kleinfelter Syndrome
183245977Chromosome Modifications and Related Syndromes1) Deletion 2) Duplication 3) Translocation 4) Inversions
183245978Pedigree AnalysisAnalyzing inheritance in existing populations rather than controlled crosses and species with long generation times
183245979Inheritence paterns for dominant autosomal Trait1) affected individuals have at least 1 affect parent 2) Phenotype expressed in each generation 3) 2 unaffected parents can only have unaffected offspring 4) number of males and females affected are approx. equal 5) most affected individuals are heterozygotes 6) Huntington Disease; Achondroplasia
183245980Inheritence patterns for recessive autosomal trait1) 2 Unaffected parents can have an affected child 2) 2 affected parents can only produce an affected child 3) Trait can skip generations 4) Cystic Fibrosis; Sickle Cell 5) Affect progency are both male and female and of equal proportions
183245981Inheritance patterns for x-linked dominant trait1) Affected males produce all affected daughters 2) Heterozygous women pass 50% of children 3) Females affected more 4) Trait present in each generation (incontentia pigmenti)
183245982Inheritence patterns for x-linked recessive trait1) Males more affected than females 2) Affected males receive from mothers, passed to daughters 3) Heterozygous daughters have 50% chance passing allele to sons 4) Trait skips generations 5) Color Blindness, Hemophillia, Duchenne Muscular Dystrophy
183245983Inheritence patterns for Y-linked traitPassed exclusively from father to son
183245984Determination of Genotype of Subjects in PedigreeGenetic information transferred via organelles Leaf vegetation transferred in genes in pastid Mammals transferred myopathy from mutation during ETC.
183346810AneuploidyLoss or gain of 1 or more chromosome
183346811Chromosome Modifications and Related SyndromesChromosome 15 - Prader Willi Syndrome/ Angelman Syndrome Chromosome 5 - Cri Du Chat Fragile X Syndrome - Martin Belle Syndrome
183346812Chromosome 15Prader Willi Syndrome - Eating Disorder (Inherits from father) Angelman Syndrome - Motor Problems, Uncontrollable Laughter (Inherits from Mother)
183346813Chromosome 5Cat like Cry small head retardation
183346814Fragile x SyndromeProtruding Chins Long narrow Face Mental retardation (common in males)
183346815DeletionLoss of a segment of a chromosome
183346816DuplicationAddition of a segment of a homologous chromosome
183346817InversionsReversal of the order of a chromosomal segment (Could alter gene expression)
183346818translocationbreakage and reattachment to a non homologous chromosome 21-14 = Downes syndrome 22-9 = Chronic Myelogenous Lukemia
183346819Chronoic Villi SamplingRetrieve and examine fetal cells for genetic abnormalities Amniocentesis - later pregnancies Chronic V - Early pregnancies
183346820allopollyploidyfollowing hydization and subsequent doubling of chromosomes Can restore fertility to a sterile hybrid
183346821AutopolyploidyResults from doubling of a chromosome set of a single species
183346822PolyPloidyDoubling the entire sets of chromosomes 3n = triploidy, 4n = tetraploidy Tumor cells 250,000 known as plants results in chromosomes not distributed to daughter cells or by nondisjunction of cells due to failure of cytokinesis after mitosis/meiosis
183346823Hybrid SterilityCaused by inability of chromosomes to pair @ prophase 1 of meiosis (Male donkey and female horse)

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