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Campbell - Chapter 17: From Gene to Protein Flashcards

GEEN to proTEEN

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1341832007in this hereditary condition, the urine is black because it contains a chemical which darkens upon exposure to airalkaptonuria0
1341832008these two scientists worked with Neurospora crassaBeadle, Tatum1
1341832009Beadle and Tatum bombarded this fungus with X-raysNeurospora crassa2
1341832010Beadle and Tatum bombarded Neurospora with theseX-rays3
1341832011Neurospora crassa can survive in the laboratory on agar, inorganic salts, glucose, and biotin, a mixture called thisminimal medium4
1341832012for Neurospora crassa, this is a minimal medium plus all amino acids and some other nutrientscomplete growth medium5
1341832013Beadle and Tatum supported the one-gene-one-___ hypothesisenzyme6
1341832014Beadle and Tatum's original idea is now stated usually as one-gene-one-___polypeptide7
1341832015ornithine becomes this, in the synthesis of argininecitrulline8
1341832016citrulline comes from this, in the synthesis of arginineornithine9
1341832017citrulline becomes this, in the synthesis of argininearginine10
1341832018arginine comes from this, in its own synthesiscitrulline11
1341832019the DNA strand that is transcribed is called the ___ strand because it provides the pattern for the sequence of nucleotides in an RNA transcripttemplate12
1341832020the term codon is also used for the DNA base triplets along the ___ strandnontemplate13
1341832021the nontemplate strand is also called the ___ strandcoding14
1341832022coding strand is also called the ___ strandsense15
1341832023nontemplate = coding = ___sense16
1341832024nontemplate = ___ = sensecoding17
1341832025___ = coding = sensenontemplate18
1341832026template = noncoding = ___antisense19
1341832027template = ___ = antisensenoncoding20
1341832028___ = noncoding = antisensetemplate21
1341832029this amino acid is coded for by one of the stop codons only in archaeapyrrolysine22
1341832030this amino acid is a component of some bacterial proteins and even some human enzymes, and is coded for by a stop codonselenocysteine23
1341832031this enzyme pries the two strands of DNA apart and joins the RNA nucleotides as they base-pair along the DNA templateRNA polymerase24
1341832032the DNA sequence where the RNA polymerase attaches and initiates transcription is known as thispromoter25
1341832033in bacteria, the sequence that signals the end of transcription is called thisterminator26
1341832034the stretch of DNA that is transcribed into RNA is called thistranscription unit27
1341832035the RNA polymerase in eukaryotes used for mRNA synthesis is called RNA pol ___II28
1341832036the whole complex of transcription factors and RNA polymerase II bound to the promoter is called thistranscription initiation complex29
1341832037this is a crucial promoter DNA sequenceTATA box30
1341832038this is the signal sequence in eukaryotes that indicates RNA polymerase to stopAAUAAA31
1341832039this is the name of AAUAAApolyadenylation (signal sequence)32
13418320405' cap is a modified form of this nucleotideG(uanine)33
1341832041are UTRs exons or introns?exons34
1341832042snRNPs stands for thesesmall nuclear ribonucleoproteins35
1341832043this is the RNA in a snRNPsnRNA36
1341832044snRNA stands for thissmall nuclear RNA37
1341832045these make up a spliceosomesnRNPs38
1341832046this process is mixing-and-matching of RNA; introns increase the probability of potentially beneficial crossing over between exons by providing more terrain for crossovers without interruptionexon shuffling39
1341832047tRNAs carry these, which base pair with their anti-namesake on RNAanticodons40
1341832048the amino acid attachment site has this sequence, from 5' to 3'CCA41
1341832049these enzymes combine amino acids and tRNAsaminoacyl-tRNA synthetases42
1341832050aminoacyl tRNA is called "___" tRNAcharged43
1341832051charged tRNA is actually ___ tRNAaminoacyl44
1341832052P in "APE" stands for thispeptidyl45
1341832053"E" in "APE" stands for this two word termexit tunnel46
1341832054in eukaryotes, the small subunit of ribosome, with the tRNA already bound, binds to this of the mRNA5' cap47
1341832055small subunit of ribosome binds to the 5' cap and then ___ downstream along the mRNA until it finds the start codonscans48
1341832056mRNA, initiator tRNA, and small ribosomal subunit is followed by attachment of large subunit, completing thistranslation intiation complex49
1341832057this molecule is used for energy to form the initiation complex of a ribosome, mRNA, and tRNAGTP50
1341832058the methionine at the amino end is called the ___-terminusN51
1341832059the final amino acid at the carboxyl end is called the ___-terminusC52
1341832060addition of an amino acid to the growing chain involves the participation of several proteins called theseelongation factors53
1341832061this number of GTP is involved in adding one amino acid to a growing chain (from discovery to addition)254
1341832062when a ribosome reaches a stop codon on mRNA, the A site of the ribosome accepts a "___" which is shaped like a tRNArelease factor55
1341832063this number of GTP is involved with dissociation of ribosome and release factor and mRNA256
1341832064strings of ribosomes are called these for shortpolysomes57
1341832065the polypeptides of proteins destined for the endomembrane system or for secretion are marked by a ___, which targets the protein to the ERsignal peptide58
1341832066this recognizes the signal peptide, bringing it to the ER membranesignal-recognition particle (SRP)59
1341832067an ER pore is actually called this, and it is what the SRP binds to after binding to the signal peptidetranslocation complex60
1341832068in hemoglobin, CTT is changed to this in sickle-cellCAT61
1341832069in hemoglobin, GAA is changed to this in sickle-cellGTA62
1341832070the mutant mRNA involved in sickle-cell is changed from GAA to thisGUA63
1341832071normal hemoglobin has a glutamic acid; sickled hemoglobin has what?valine64
1341832072sickled hemoglobin has a valine; normal hemoglobin has what?glutamic acid65
1341832073incorrect bases, if uncorrected, can be used as a template in the next round of replication, resulting in a ___ mutationspontaneous66
1341832074these agents interact with DNA in ways tat cause mutationsmutagens67

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