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AP Bio - Cellular Communication Flashcards

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5893397075Local SignalsCells communicating by direct contact0
5893397076Local RegulatorsMessenger molecules that travel short distances1
5893397077Paracrine SignalingLocal regulator released directly onto one cell by another2
5893397078Synaptic SignalingA nerve signal triggers the release of a local regulator onto a nearby cell3
5893397079HormonesChemical messengers that travel a long distance4
5893397080Signal Transduction PathwaySet of a step that triggers after a signal is received, it activates a certain response from a cell.5
5893397081ReceptionDelivery of a signal to a cell6
5893397082LigandsSignal Molecules, hormones.7
5893397083G protein-coupled-receptorMembrane receptor that activates a G protein when a ligand is present.8
5893397084G ProteinWhen activated, uses energy from GDP becoming GTP to turn on an enzyme.9
5893397085Receptor Tyrosine KinaseMembrane receptors that attach phosphates to tyrosines10
5893397086DimerWhen a ligand is present the two kinases form this, then trigger multiple transduction pathways.11
5893397087Ligand-gated Ion ChannelReceptor opens like a gate when a ligand is present to allow ions in12
5893397090Protein Kinasestransfer phosphates from ATP to protein (phosphorylation)13
5893397092Second MessengersSmall molecules that diffuse throughout the cell to carry the signal during transduction.14
5893397093ApoptosisControlled cellular death15
5893397094First Line of DefenseNonspecific barrier to keep out pathogens ex: skin, stomach acid, mucous membrane, cilia16
5893397095Second Line of DefenseNonspecific defense and inflammatory response initiated by chemical signals to attack and isolate invading pathogens17
5893397096Inflammatory Responsenonspecific defense against infection, characterized by redness, heat, swelling, and pain18
5893397097Histamineschemical signals that trigger vasodilation, increasing blood supply to area19
5893397098PhagocytesWhite blood cells that engulf invading pathogens e.g., neutrophils, macrophages20
5893397099Chemokineschemical signals secreted by blood vessel cells that attract more white blood cells (phagocytes) to the area21
5893397101Adaptive immunity(specific immunity) aquired ability to recognize and destroy a pathogen or its products. Requires exposure of the immune system to the pathogen22
5893397102LymphocyteWhite blood cell23
5893397103B CellsHumoral response by producing antibodies; activated by Helper T cells or free antigens24
5893397104T CellsCells created in the thymus that produce substances that attack infected cells in the body.25
5893397105Helper T CellSet off an alarm to the immune system that pathogens have broken through the body's line of defense; binds to class II MHC26
5893397106Cytotoxic T CellKills body cells that have been infected with pathogens; stimulated by antigens and helper T-cells27
5893397107MacrophagesCan engulf and digest pathogens and signal to the rest of the immune system that there is an invader28
5893397110Memory CellsResponsible for lifelong immunity by storing copy B and T cells to more quickly fight secondary infection29
5893397111AntibodyY-shaped protein with variable antigen bind region; slows pathogens to facilitate destruction30
5893397112AntigenIdentifying marker on the outside of a pathogen31
5893397113Passive ImmunityTemporary immunity where antibodies are transferred from another animal ex: mother transfers some of her antibodies to her nursing child32
5893397115Autoimmune diseaseA mistake in the immune system where the body does not properly distinguish self from nonself and attacks its own body cells33
5893397117Endocrine SystemReleases hormones, chemicals released by *ductless glands* into the blood stream that can have an effect anywhere in the body34
5893397118Tropic hormonesHormones that stimulate other endocrine glands to release their hormones35
5893397119PheromonesHormones released by one animal that affect other animals36
5893397132Positive FeedbackA type of regulation that responds to a change in conditions by initiating responses that will amplify the change. Takes organism away from a steady state.37
5893397133Negative FeedbackMetabolic pathway that helps maintain homeostasis38
5893593317cAMP molecule(Cyclic adenosine monophosphate) a second messenger important for intracellular signal transduction39

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