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AP BIology DNA Replication Flashcards

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6328556528DNA Replicationthe process by which a DNA molecule is copied; also called DNA synthesis0
6328556529Double helixtwo strands1
6328556530Antiparallelsubunits run in opposite directions2
6328556531Nitrogenous bases of DnaA, T, C, G3
6328556532PurinesA and G Nitrogenous bases with two organic rings4
6328556533PyrimidinesC and T Nitrogenous base with a single organic ring5
6328556534Semiconservative Modelthe two strands of the parental molecule separate and each functions as a template for synthesis of a new complementary strand- most common6
6328556535Origins of Replicationshort stretches of DNA having a specific sequence of nucleotides7
6328556536Replication Forka Y shaped region where the parental strands of DNA are being unwound8
6328556537Helicasesenzymes that untwist the double helix at the replication forks, separating the two parental strands and make them available as template strands9
6328556538Single Strand Binding ProteinsBind to the unpaired DNA strands keeping them from repairing10
6328556540PrimaseSynthesizes the primer Starts a complementary RNA chain from a single RNA nucleotide, adding more RNA nucleotides one at a time, using the parental DNA strand as a template11
6328556541DNA polymerasesEnzyme that catalyze the synthesis of new DNA by adding nucleotides to a preexisting chain12
6328556542Leading strandStrand that continuously adds nucleotides to the new complementary strand as the fork progresses DNA pol III13
6328556543Lagging StrandThe strand that DNA pol III works away from the replication fork Synthesized discontinuosly as a series of segments14
6328556544Okazaki fragmentsSeries of segments that are 1000-2000 nucleotides long15
6328556545DNA Ligasejoins the sugar phosphate backbones of all the Okazaki fragments into a continuous DNA strand16
6328556546DNA polymerase IIISynthesizes new DNA strands by adding nucleotides to an RNA primer or a pre-existing DNA strand17
6328556547DNA polymerase IRemoves RNA nucleotides of primer from 5' end and replaces them with DNA nucleotides18
6328556548NucleaseDNA cutting enzyme that cuts out the damaged parts of the strand and fills the space with nucleotides using the undamaged strand as a template19
6328556549TelomeresSpecial nucleotide sequences at the ends of chromosomes TTAGGG is repeated between 100-1000 times Prevent the staggered ends of daughter molecule from activitating cell's system for monitoring DNA damage20
6328556550HistonesProteins that are responsible for the first level of DNA packing in chromatin21
6328556551Chromatincomplex of DNA and protein22

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