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AP Mitosis and Meiosis Flashcards

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5991289982Purpose of Mitosis-Growth -Repair -Replacement -Create 2 identical cells0
5991289983Parts of the Cell CycleInterphase- G1, S, G2, and G0 Mitosis (M)- Prophase, Metaphase, Anaphase, Telophase Cytokinesis1
5991289984What happens in each part of the Cell CycleInterphase: G1- Cell doing it's thing, first gap, cell grows, DNA in the form of chromatin S- DNA is replicated G2- Prep for cell division, and more growing occurs G0- Non-dividing state Mitosis (M): Cell Division Prophase- Chromatin condenses into distinct chromosomes, nuclear membrane is gone, spindle fibers form as well as centrioles Metaphase- Spindles are attached at the centromere, chromosomes line up in the middle (equator) Anaphase- Chromosomes are pulled apart by the spindles and move towards opposite poles Telophase- Cell starts to split by a wall or cleavage furrow, nuclear membrane reappears Cytokinesis: Splitting of the Cytoplasm2
5991289985Steps of Mitosis and what happens in eachEarly Prophase- Chromatin condenses into chromosomes Late Prophase- Distinct chromosomes, nuclear membrane gone, spindle fibers, and centrioles Metaphase- Spindles are attached at the centromere, chromosomes line up in the middle (equator) Anaphase- Chromosomes are pulled apart by the spindles and move towards opposite poles Telophase- Cell starts to split by a wall or cleavage furrow, nuclear membrane reappears3
5991289986Longest phase of MitosisProphase4
5991289987Shortest Phase of MitosisAnaphase5
5991289988Structure of the Mitotic Spindles: Role of the CentrosomesA sub-cellular region containing material that functions throughout the cell cycle yo organize the cells microtubules Another name is the microtubule-organizing center6
5991289990Structure of the Mitotic Spindles: Role of the MicrotubulesRope like components, they are used to position the chromosomes at a specific spot in the cell. They are also used to increase or decrease the tension on each side of the chromosome7
5991289991Structure, Function, and Location of KinetochoresStructure- Structure made up of proteins Function- Where microtubules attach to the centromeres of the chromatids Location- Assembled on specific sections of DNA at the centromere8
5991289993ChromosomePacked DNA in structures9
5991289994Sister ChromatidsTwo identical copies of a chromosome that are connected by a centromere10
5991289995Daughter ChromosomesA chromosome that results from the separation of the sister chromatids during cell division11
5991289996Difference in Mitosis in Plant and Animal CellsPlant: During Telophase, a cell plate separates the cytoplasm and 2 cells Animal: During Telophase, the cell membrane begins to pinch together (cleavage furrow), and separates the one cell to create 2 cells12
5991289997Ploidy NumbersA measure of the number of chromosomes in a cell13
5991289998Chromosome numbersBefore Mitosis: 46 (2n) During Mitosis: 46 (2n) After Mitosis: 46 (2n)14
5991289999Difference in Bacteria Replication and EukaryotesBacteria Replication- -occurs inside the cytoplasm -replication is very rapid Eukaryotes replication- -occurs inside the nucleus -replication is slow15
5991290000Cell Cycle Control System and CheckpointsCell Cycle Control System- What they are: the system that controls the cell cycle and is driven by specific signaling molecules present in the cytoplasm Checkpoints- What they are: a control point in the cell cycle where stop and go-ahead signals can regulate the cycle16
5991290001CyclinsGroup of proteins that control the development of cells through the cell cycle by activating cyclin-dependent kinase.17
5991290002Cyclin-Dependent KinasesGroup of proteins that regulate the cell cycle. Involved in transcription, mRNA processing, and the differentiation of the nerve cells.18
5991290003Example of the molecular control of the cell cycle at the G2 checkpoint (including MPF)G2 checkpoint: maturation-promoting factor (MPF)- which triggers the cells passage into the (m) phase past the G2 checkpoint, cyclin-dependent kinases Goes from G2 to Mitosis19
5991290004External Signals: Growth FactorsA protein released by certain cells that stimulate other cells to divide20
5991290007Role of the Cell Cycle in CancerThe cell cycle is the production of making more cells and cancer is uncontrolled cell growth21
5991290008Role of genes and Mutations in the cell cycle in cancerMutations are caused by extrinsic factors and those increase risk of cancer22
5991290009Three extrinsic factors that can cause cancer and how1- Chemicals (smoking) 2- Radiation 3- Viruses 4- Bacteria Why there can be a lag time between exposure and cancer- Because this is the period between exposure and onset of disease23
5991290010Relationship between time and the survival ratesquicker the cancer is found in time in an earlier stage, the longer survival rate one would have24
5991290011Benign TumorA tumor that can't spread by invasion or metastasis to other areas25
5991290012Malignant TumorA tumor that can spread by invasion or metastasis to other areas of the cell26
5991290013MetastasisThe ability of cancer cells to penetrate into blood vessels, circulate the blood stream, and then invade normal tissue elsewhere27
5991290014ApoptosisProgrammed cell death, cell suicide28
5991290017BiopsyThe removal of a piece of tissue for microscopic examination29
5991290018CarcinomaAn uncontrolled growth of cells that remains in original location30
5991290019OncogeneDamaged genes that help develop cancer31
5991290020CarcinogenAny substance that has the potential to cause cancer in living tissues32
5991290022drawn examples of the stages of Mitosis33
5991290023Cell in Interphase34
5991290024Cell in Prophase35
5991290025Cell in Metaphase36
5991290026Cell in Anaphase37
5991290027Cell in Telophase38
5991290028GametesA reproductive cell- sperm or egg39
5991290029Somatic CellsAll other body cells besides reproductive40
5991290030KaryotypeVisual expression of chromosomes that have paired up, or the chromosome complement of a cell or a whole organism41
5991290031Homologous ChromosomesA chromosome with the same gene sequence as another, each derived from one parent42
5991290032Homologssame thing as a homologous chromosome, A chromosome with the same gene sequence as another, each derived from one parent43
5991290033Autosomeschromosomes other than the sex chromosomes44
5991290034Sex ChromosomesDetermine the sex of a person, XY= male XX=female45
5991290035Diploid(2n), 2 of the halves, full set of genetic information46
5991290036Haploid(1n), half of the genetic information47
5991290037Fertilizationmerging of 2 haploid cells48
5991290038Zygoteearly stage development of an organism49
5991290039GeneThe set of information that controls a trait;a segment of DNA on a chromosome that codes for a specific trait.50
5991290041VariationThe differences that occur in individuals within a species51
5991290043Asexual ReproductionAdvantages- can reproduce twice as many, does not require fertilization, can quickly occur, don't need mate Disadvantages- reproduction is based on amount of food, very little variation52
5991290044Sexual ReproductionAdvantages- more genetic variation, children are different from parents, able to produce more offspring because of mate Disadvantages- slower reproduction rate, less reliable, takes time and energy to find mate53
5991290046RecombinationNew allele combinations produced by crossing over, source that results in the variation in population gene pools54
5991290047Recombinant ChromosomesWhen genetic material combine in which half is from the mother and half is from the father and makes a new chromosome55
5991290048SynapsisOccurs in Prophase of Meiosis 1, the homlogs pair up to form bivalents56
5991290049ChiasmaRegions where non-sister chromatids become entangled and the chromosomes exchange segments, place of crossing over57
5991290050TetradA group of 4 closely associated chromatids of a homologous pair formed by synapsis, copied chromosomes58
5991290051"n"half of the genetic information, haploid59
5991290052MeiosisPurpose- Sex cell division Product- 4 gametes used in fertilization Location of Occurrence- within the testes and the ovaries60
5991290053Number of human Chromosome pairs23 pairs61
5991290054Number of human Chromosomes46 individual62
5991290055Number of human chromosomes in cells of meiosisAt Beginning- (2n) or 46 At End-(n) or 2363
5991290056Relationship between genetic diversity and MeiosisWays that Meiosis increases Genetic Diversity- because of crossing over and the fact that individual genes come from 2 different places and combine together64
5991290057Crossing OverWhen- Prophase of Meiosis 1 Where- at the Chiasma site How- non-sister Chromatids become entangled and the chromosomes exchange segments65
5991290058Genetic RecombinationWhen- During Meiosis 1 Where-Anaphase How- New allele combinations produced by crossing over, source that results in the variation in population gene pools66
5991290059Ploidy number during meiosisBefore-(2n) or 46 After-(n) or 2367
5991290060The Stages of Meiosis and what happens in eachMeiosis 1: Prophase- Chromatin condenses into distinct chromosomes, nucleus disappears, spindle fibers form as well as centrioles, chromosomes are a tetrad Metaphase- Spindles are attached at the centromere, chromosomes line up in the middle (equator) Anaphase- Chromosomes are pulled apart by the spindles and move towards opposite poles Telophase- Cell starts to split by a cleavage furrow, nuclear membrane reappears Cytokinesis: Splitting of the Cytoplasm Meiosis 2: -same steps as Meiosis 1 except for at the end instead of producing 2 haploid cells, either creates 4 sperm by spermatogenesis or 1 egg and 3 polar bodies by oogenesis68
5991290061Purpose of Meiosis 1To create 2 haploid cells each with 2 sister chromatids per chromosome69
5991290062Purpose of Meiosis 2To create 4 haploid cells with each chromosome consisting of a single chromatid70
5991290063Significant events of Prophase in Meiosis 1Where crossing over occurs and in result ensures that each sex cell is unique, chromosomes are tetrad71
5991290064The difference between Metaphase of Meiosis 1 and MitosisIn Meiosis 1, homologous chromosomes line up in the middle whereas in mitosis individual chromosomes line up in the middls72
5991303061anaphaseStage of mitosis during which sister chromatids separate and move to opposite spindle poles.73
5991303062asexual reproductionReproductive mode by which offspring arise from a single parent only.74
5991303063cell cycleA series of events from the time a cell forms until its cytoplasm divides.75
5991303064cell plateAfter nuclear division in a plant cell, a disk-shaped structure that forms a cross-wall between the two new nuclei.76
5991303065cleavage furrowIn a dividing animal cell, the indentation where cytoplasmic division will occur.77
5991303066cytokinesisCytoplasmic division.78
5991303067growth factorMolecule that stimulates mitosis and differentiation.79
5991303068homologous chromosomesChromosomes with the same length, shape, and set of genes.80
5991303069interphaseIn a eukaryotic cell cycle, the interval between mitotic divisions when a cell enlarges, roughly doubles the number of its cytoplasmic components, and replicates its DNA.81
5991303070metaphaseStage of mitosis at which the cell's chromosomes are aligned midway between poles of the spindle.82
5991303071metastasisThe process in which cancer cells spread from one part of the body to another.83
5991303072mitosisNuclear division mechanism that maintains the chromosome number. Basis of body growth and tissue repair in multicelled eukaryotes; also asexual reproduction in some plants, animals, fungi, and protists.84
5991303073neoplasmAn accumulation of abnormally dividing cells.85
5991303074oncogeneGene that helps transform a normal cell into a tumor cell.86
5991303075prophaseStage of mitosis during which chromosomes condense and become attached to a newly forming spindle.87
5991303076proto-oncogeneGene that, by mutation, can become an oncogene.88
5991303077spindleDynamically assembled and disassembled network of microtubules that moves chromosomes during nuclear division.89
5991303078telomereNoncoding, repetitive DNA sequence at the end of chromosomes; protects the coding sequences from degradation.90
5991303079telophaseStage of mitosis during which chromosomes arrive at the spindle poles and decondense, and new nuclei form.91
5991303080tumorA neoplasm that forms a lump.92
5991303082crossing overProcess in which homologous chromosomes exchange corresponding segments during prophase I of meiosis.93
5991303083eggMature female gamete, or ovum.94
5991303084fertilizationFusion of two gametes to form a zygote.95
5991303085gameteMature, haploid reproductive cell; e.g., an egg or a sperm.96
5991303086gametophyteA haploid, multicelled body in which gametes form during the life cycle of land plants and some algae.97
5991303087germ cellImmature reproductive cell that gives rise to haploid gametes when it divides.98
5991303088haploidHaving one of each type of chromosome characteristic of the species.99
5991303089meiosisNuclear division process that halves the chromosome number. Basis of sexual reproduction.100
5991303090sexual reproductionReproductive mode by which offspring arise from two parents and inherit genes from both.101
5991303091somaticRelating to the body.102
5991303092spermMature male gamete.103
5991303093sporophyteDiploid, spore-producing stage of a plant life cycle.104
5991303094zygoteDiploid cell formed by fusion of two gametes; the first cell of a new individual.105

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