BIOLOGY NOTES MONDAY 17, 2014 (CHAPTER 11) 6 Characteristics of cancerous cells Grow when should not Continue to grow when other cells send ?stop? signals When change in their DNA, Apoptosis doesn?t occur Can co-opt vascular system creating new blood vessels Immortal (MOST IMPORTANT) Can metastasis, which moving to other parts Mutations in 2 types of genes cause cancer Positive growth regulators Negative growth regulators Explain how the mutations cause runaway all proliferation More positive growth, results in hyperactivity Uncontrolled cell division, No brakes 2 types of genes Proto-oncogene- Normal Function- Promote cell division (code for positive growth regulator) Mutation- Runaway cell division causing hyperactivity