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DNA Transcription (Slide 20) The ?Central Dogma? - Crick 1958 DNA - RNA - Protein Proposed that this process could not go backwards The part of DNA that encodes for a protein (or RNA) is called a gene GENE: Functional unit of DNA that codes for one or more polypeptide chains or an RNA molecule Genome is not just genes, there are intervening sequences that don?t code for a protein Proteins are generated through transcription and translation How much protein is present can be regulated by the amount of transcription and/or translation Beta-catenine- high abundance in brain (A) but low abundance in muscle (B) DN A is transcribed by RNA polymerase One RNA polymerase in bacteria that does all the transcription CORE ENZYME: 2?, 1?, 1??

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