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ATP and Biochemical Pathways

adenosine triphosphate (ATP) - main energy currency used in cells 

  • made of ribose, adenine (w/ 2 C-N rings), triphosphate group
  • adenine forms the base, attracting hydrogen ions
  • phosphates joined by unstable bonds, repelling each other
  • energy of repulsion stored in bonds that hold phosphates together
  • transferring a phosphate group transfers energy
  • bonds easily broken, easily turned into adenosine diphosphate (ADP)
  • nearly all endergonic reactions require less energy than provided by cleavage of ATP
  • enzymes catalyzing endergonic reactions have 2 binding sites: 1 for reactant, other for ATP
  • most cells only contain a few seconds' supply of ATP at a time

metabolism - all chemical reactions carried out by an organism  

  • anabolism - reactions that use energy to make/change bonds
  • catabolism - reactions that produce energy when breaking chemical bonds

biochemical pathways - sequence of reactions; organizational metabolic units  

  • product of 1 reaction becomes substrate for next reaction
  • evolved from a need of certain substances (new reactions would start when a certain substance was lacking)
  • wasteful if more compounds than needed were produced
  • feedback inhibition - where final product acts as an inhibitor on the chemical pathway, shutting it off when enough product has been created
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