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AP Bio Campbell 7e Chapter 12 Flashcards

Key terms/ideas

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578108644cell divisionreproduction of cells
578108645cell cyclelife of a cell from the time it first forms to its own division
578108646genomecell's endowment of DNA in prokaryotes: long DNA molecule
578108647chromosomeswhat DNA is packaged into each eukaryote has its own characteristic number
578108648somatic cellsall body cells humans have 46 in the nucleus
578108649gametesreproductive cells half as many chromosomes
578108650chromatincomplex of DNA long and complicated; needs to be condensed
578108651sister chromatidshave identical DNA each chromosome has 2 attached by adhesive proteins
578108652centromereattaches two sister chromatids together
578108653mitosisdivision of the nucleus PMAT
578108654cytokinesisdivision of the cytoplasm
578108655meiosisyields non-identical daughter cells with half the number of chromosomes as parent cell
578108656mitotic (M) phaseincludes mitosis and cytokinesis shortest part of the cell cycle
578108657interphaselongest phase (90% of the cycle) includes G1, S, and G2 cell prepares itself for division
578108659Scell duplicates its chromosomes
578108660G2cell duplicates proteins and organelles prepares to divide
578108661mitotic spindlemitosis depends on this begins to form in the cytoplasm during prophase consists of microtubules, centrosomes, and asters
578108662centrosomewhere the mitotic spindle starts to assemble organizes microtubules
578108663asterarray of short microtubules at each pole of the dividing cell
578108664kinetochorea structure of proteins attached to sister chromosomes spindle microtubules extend to them during metaphase
578108665metaphase platewhere chromosomes line up during metaphase
578108666cleavage furrowduring cytokinesis groove, indent on cell surface near the metaphase plate
578108667cell platein plant cells microtubules line the middle of the cell when is fully formed, cell division is complete
578108668binary fissionhow prokaryotes divide have one long strand of DNA to divide
578108669origin of replicationlocation on the chromosome where DNA begins to replicate in prokaryotes
578108670cell cycle control systemset of molecules that trigger and organize cell cycle
578108671checkpointcritical point where signals regulate the cycle from transduction pathways if doesn't pass, can't continue dividing
578108672G0non dividing state nerve and muscle cells most cells are like this
578108673CDKscyclin dependent kinases activity rises and falls with the concentration of cyclin cyclin activates it
578108674cyclinconcentration fluctuates in the cell activates CDKs highest concentration during interphase, then drops during mitosis
578108675MPFmetaphase promoting factor first CDK discovered destroys cyclin in anaphase
578108676growth factorprotein that stimulates cell division
578108677density dependent inhibitionwhen too crowded, cells stop dividing
578108678anchorage dependencemust be attached to a substrate in order to divide
578108679transformationnormal cell turns into a cancer cell
578108680malignant tumorcancer spreads to one or more organs
578108681metastasiscancer is spread to different locations through the blood stream
578140426G1cell grows
578140427prophasechromatin fibers become tightly coiled each duplicated chromosome appears as sister chromatids mitotic spindle begins to form centrosomes move away from each other
578140428prometaphasemicrotubules reach towards chromosomes from the centromeres
578140429metaphaselongest stage of mitosis centrosomes at opposite ends of the cell chromosomes go to metaphase plate kinetochore spindles attach to sister chromatid kinetochores
578140430anaphaseshortest stage of mitosis two sister chromatids are pulled away from each other cell elongates
578140431telophasetwo daughter nuclei begin to form in the cell chromosomes become less condensed nuclear envelop begins to reform
578140432cytokinesiscytoplasm finishes dividing

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