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AP bio - DNA replication

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52665906euchromatina region of DNA that is uncoiled and undergoing active transcription into RNA
52665907heterochromatinDensely staining condensed chromosomal regions, believed to be for the most part genetically inert. chromatin that remains tightly coiled (and darkly staining) throughout the cell cycle.
52665908double helixThe form of native DNA, referring to its two adjacent polynucleotide strands wound into a spiral shape.
52665909nucleotidesBasic units of DNA molecule, composed of a sugar, a phosphate, and one of 4 DNA bases
52665910DNA basesadenine, guanine, cytosine, thymine
52665911complementary base pairingadenine form hydrogen bonds with thymine, cytosine forms hydrogen bonds with guanine
52665912phosphodiester bondsbonds that join nucleotides in nucleic acids
52665913antiparallelThe opposite arrangement of the sugar-phosphate backbones in a DNA double helix.
52665914ribonucleic acid(RNA) part of the genetic material that organisms inherited from their parents
52665915helicasean enzyme that untwists the double helix at the replication forks, separating the two parental strands and making them available as template strands
52665916replication forkA Y-shaped region on a replicating DNA molecule where new strands are growing.
52665917topoisomeraseA protein that functions in DNA replication, helping to relieve strain in the double helix ahead of the replication fork.
52665918DNA polymeraseAn enzyme that catalyzes the elongation of new DNA at a replication fork by the addition of nucleotides to the existing chain.
52665919RNA primaseAn enzyme that creates an RNA primer for initiation of DNA replication.
52665920leading strandthe new continuous complementary DNA strand synthesized along the template strand in the mandatory 5' --> 3' direction
52665921lagging strandThe strand in replication that is copied 3' to 5' as Okazaki fragments and then joined up.
52665922okazaki fragmentsShort fragments of DNA that are a result of the synthesis of the lagging strand during DNA replication.
52665923DNA ligasean enzyme that eventually joins the sugar-phosphate backbones of the Okazaki fragments
52665924semiconservativerefers to the fact that half of a newly made DNA is the old template.
52665925ribosea pentose sugar important as a component of ribonucleic acid
52665926uracila nitrogen-containing base found in RNA (but not in DNA) and derived from pyrimidine
52665927mRNAA type of RNA, synthesized from DNA, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein; also called messenger RNA.
52665928rRNAThe most abundant type of RNA, which together with proteins froms the structure of ribosomes. Ribosomes coordinate the sequential coupling of tRNA molecules to mRNA codons; also called ribosomal RNA.
52665929tRNAThe type of RNA that binds to specific amino acids and transports them to the ribosome during protein synthesis
52665981protein synthesisthe formation of proteins by using information contained in DNA and carried by mRNA
52665982transcriptionprocess in which part of the nucleotide sequence of DNA is copied into a complementary sequence in RNA
52665983translation(genetics) the process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm
52665984sense strandThe strand of DNA that has the code for protein
52665985antisense strandstrand of DNA that is NOT transcribed
52665986RNA polymerasean enzyme that pries the 2 strands of DNA apart and hooks together the RNA nucleotides as they base pair along the DNA template
52665987exonsexpressed sequence of DNA; codes for a protein
52665988intronssequence of DNA that is not involved in coding for a protein
52666470poly(A) tailAfter an mRNA is transcribed from a gene, the cell adds a stretch of A residues (typically 50-200) to its 3' end.
526664715' capwhen pre-mRNA is modified the 5 primed end is synthesized first; it is a modified form of a guanine nucleotide
52666472codonsA three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code.
52666473anticodongroup of three bases on a tRNA molecule that are complementary to an mRNA codon
52666474A siteholds the tRNA carrying the next amino acid to be added to the chain
52666475P siteone of a ribosome's three binding sites for tRNA during translation. It holds the tRNA carrying the growing polypeptide chain.
52666476E siteOne of a ribosome's three binding sites for tRNA during translation. This site is the place where discharged tRNAs leave the ribosome.
52666604peptide bondcovalent bond formed between amino acids
52666605polypeptideA polymer (chain) of many amino acids linked together by peptide bonds.
52666606stop codonsUAA, UAG, UGA
52666607chaperoninsprotein molecules that assist the proper folding of other proteins
52666608chaperon proteinsa type of protein that helps denatured proteins fold correctly
52666609mutationchange in a DNA sequence that affects genetic information
52702911genetic codethe ordering of nucleotides in DNA molecules that carries the genetic information in living cells
52702912point mutationsgene mutations involving changes in one or a few nucleotides
52702913frameshiftA nucleotide is inserted or deleted, changing where the coding for entirely different amino acids.
52702914missensesingle base change results in the inclusion of a different amino acid
52702915nonsenseA new nucleotide replaces an existing one and changes the codon so that it codes for the end of the strand with TAA, TAG, or TGA.

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