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AP Biology Cell Cycle Flashcards

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8664701418MitosisCell division that produces normal cells, produces two identical daughter cells.0
8664701420CentriolesIn animal cells, they organize microtubules into spindle fibers. These guide chromosomes in mitosis.1
8664701421IPMATPneumonic device to remember the stages and order of cell division: Interphase, Prophase, Metaphase, Anaphase, and Telophase.2
8664701422Interphase90% of the cell cycle. The cell does its "everyday job": RNA is produced, proteins are synthesized. The cell is preparing for duplication -- it is ready whenever it is triggered.3
8664701423G1 PhaseInitiated by a signal to divide. 1st growth period of the cell. Cell does its "everyday job." Cell grows, preparing for division.4
8664701424S PhaseDNA Synthesis. The cell copies chromosomes.5
8664701425ChromatinThe DNA-Protein complex formed when DNA molecules wrap around histone proteins.6
8664701426ChromosomesA doubled rod of condensed chromatin; contains DNA that carries genetic information.7
8664701428CentromeresArea where the chromatids of a chromosome are attached.8
8664701429Sister ChromatidsReplicated forms of a chromosome joined together by the centromere and eventually separated during mitosis.9
8664701430Homologous ChromosomesChromosomes that have the same sequence of genes, that have the same structure and code for the same gene, but may have different alleles.10
8664701431G2 PhaseThe cell prepares for division. Cell grows even more. Produces more organelles, proteins, and membranes.11
8664701432ProphaseChromatin condenses. Centrioles move to opposite poles of cell. Protein fibers cross cell to form mitotic spindle. Nuclear membrane breaks down.12
8664701435spindlefanlike microtubule structure that helps separate the chromosomes during mitosis13
8664701436MetaphaseChromosomes align along middle of cell, ensuring chromosomes separate properly.14
8664701438AnaphaseSister chromatids separate, poles move farther apart.15
8664701440TelophaseChromosomes arrive at opposite poles. Spindle fibers disperse. Cytokinesis begins.16
8664701446CancerA collection of related diseases in which cells divide uncontrollably17
8664701447G1Checkpoint where if cell is not ready to divide it may arrest here (G0 phase - nerve and muscle cells remain here, rarely divide after maturing) and never proceed or wait until it is ready.18
8664701448SDNA damage checkpoint: DNA recplication halted if genome is damage19
8664701449cyclinone family of proteins that regulates the cell cycle in eukaryotic cells20
8664701468MetastasisThe spread of cancer cells beyond their original site21
8664701469density-dependent inhibitioncrowded cells stop dividing22
8664701470anchorage dependenceThe requirement that to divide, a cell must be attached to a solid surface.23
8664701471tumor-suppressor genesa gene whose protein product inhibits cell division, thereby preventing the uncontrolled cell growth that contributes to cancer (ex p53)24
8664701472Proto-oncogenesGenes that stimulate mitosis25

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