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AP Biology Ch 16: Mutation Types Flashcards

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8692771653Mutationa change in the genetic material of a cell; cause by a mistake during DNA replication.0
8692771654Gene Mutationschanges to a single gene.1
8692771655Point Mutationinvolve changes in one or a few nucleotides/bases.2
8692771656Substitution Mutationone base is changed to a different base (May or may not affect the amino acid due to redundancy in the genetic code).3
8692771657Insertionadds a new base to the DNA sequence4
8692771658Deletionremoves a base from the DNA sequence5
8692771659Frameshift Mutationcaused by insertions and deletions that changes the reading sequence. Usually causes a significant change in the amino acid sequence.6
8692771660Chromosomal mutationchange in the number or structure of a chromosome. Change the location of genes on a chromosome Change the number of copies of genes.7
8692771661What are the four chromosomal mutations?Deletion Duplication Inversion Translocation8
8692771662Duplicationextra copy of all or part of a chromosome9
8692771663Inversionpart of a chromosome switches direction.10
8692771664Translocationpart of one chromosome breaks off and attaches to another chromosome.11
8692771666Chromosomal Disordersentire chromosomes, or large segments of them are missing or duplicated.12
8692771667Nondisjunctionchromosomes do not separate during meiosis; extra or missing chromosomes.13
8692771668Reciprocal Translocationpart of a chromosome breaks off an attaches to another chromosome, but in this case it is equal amounts between homologous chromosomes. AKA Crossing over- totally normal14
8692771669Silent mutationmutations in DNA that do not significantly alter the phenotype of the organism in which they occur15
8692771670trisomythere are three copies of a particular chromosome, instead of the normal two16
8692771671monosomythe condition of having a diploid chromosome complement in which one (usually the X) chromosome lacks its homologous partner.17
8692771674Karyotypethe number and visual appearance of the chromosomes in the cell nuclei of an organism or species.18
8692771676Mutagenan agent, such as radiation or a chemical substance, that causes genetic mutation.19

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