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AP Biology - Chapter 11 Flashcards

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5126772613signal transduction pathwaya series of steps linking a mechanical or chemical stimulus to a specific cellular response0
5126772614local regulatorsa secreted molecule that influences cells near where it is secreted (the red stuff)1
5126772615cell junctionsallows molecules to pass readily between adjacent cells without crossing plasma membranes2
5126772616cell-cell recognitiontwo cells in an animal may communicate by interaction between molecules protruding from their surfaces3
5126772617paracrine signaling(local) a secreting cell acts on nearby target cells by discharging molecules of a local regulator4
5126772618synaptic signaling(local) a nerve cell releases neurotransmitter molecules into a synapse, stimulating the target cell5
5126772619hormonal signalingspecialized endocrine cells secrete hormones into body fluids, often the blood6
5126772620hormonesin multicellular organisms, one of many types of secreted chemicals that are formed in specialized cells, travel in body fluids, and act on specific target cells in other parts of the body to change their functioning7
5126772621reception8
5126772622transduction9
5126772623response10
5126772624liganda molecule that binds specifically to another molecule, usually a larger one11
5126772625g protein-coupled receptora signal receptor protein in the plasma membrane that responds to the binding of a signaling molecule by activating a G protein12
5126772626g protein-coupled receptor13
5126772627g proteina GTP-binding protein that relays signals from a plasma membrane signal receptor, known as a G protein-coupled receptor, to other signal transduction proteins inside the cell14
5126772628receptor tyrosine kinasesa receptor protein in the plasma membrane, the intracellular part of which can catalyze the transfer of a phosphate group from ATP to a tyrosine on another protein15
5126772629receptor tyrosine kinasesoften respond to the binding of a signaling molecule by dimerizing and then phosphorylating a tyrosine on the cytoplasmic portion of the other receptor in the dimer; phosphorylated tyrosines on the receptors then activate other signal transduction proteins within the cell16
5126772630receptor tyrosine kinases17
5126772631ligand-gated ion channela protein pore in cellular membranes that opens or closes in response to a signaling chemical (its ligand), allowing or blocking the flow of specific ions18
5126772632ligand-gated ion channel19
5126772633steroid hormone interacting with an intracellular receptor20
5126772634protein kinasean enzyme that transfers phosphate groups from ATP to a protein, thus phosphorylating the protein21
5126772635protein phosphatasesan enzyme that removes phosphate groups from (dephosphorylates) proteins, often functioning to reverse the effect of a protein kinase22
5126772636phosphorylation cascade23
5126772637second messengersa small, nonprotein, water-soluble molecule or ion, such as a calcium ion (Ca2+) or cyclic AMP, that relays a signal to a cell's interior in response to a signaling molecule bound by a signal receptor protein24
5126772638cyclic ampcyclic adenosine monophosphate, a ring-shaped molecule made from ATP that is a common intracellular signaling molecule (second messenger) in eukaryotic cells; also a regulator of some bacterial operons25
5126772639adenylyl cyclasean enzyme that converts ATP to cyclic AMP in response to a signal26
5126772640cAMP as a second messenger in a G-protein signaling pathway27
5126772641calcium ionsmany signaling molecules in animals, including neurotransmitters, growth factors, and some hormones, induce responses in their target cells via signal transduction pathways that increase the cytosolic concentration of28
5126772642morecalcium is (more/less) widely used than cAMP as a second messenger29
5126772643the maintenance of calcium ion concentrations in an animal cell30
5126772644IP3 (inositol triphosphate)a second messenger that functions as an intermediate between certain nonsteroid hormones and a third messenger, a rise in cytoplasmic calcium ion concentration31
5126772645DAG (diacyglycerol)a second messenger produced by the cleavage of a certain kind of phospholipid in the plasma membrane32
5126772646calcium and IP3 in signaling pathways33
5126772647the specificity of cell signaling34
5126772648scaffolding proteinsa type of large relay protein to which several other relay proteins are simultaneously attached, increasing the efficiency of signal transduction35
5126772649apoptosisa program of controlled cell suicide, which is brought about by signals that trigger the activation of a cascade of suicide proteins in the cell destined to die36
5126772650apoptosis37

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