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AP Biology Chapter 16 Flashcards

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12780637852DNA replicationThe process by which a DNA molecule is copied; also called DNA synthesis0
12780637853transformationIn incorporation of external DNA into an organism's genome1
12780637854bacteriophageA virus that infects bacteria; also called a phage2
12780637855virusAn infectious particle incapable of replicating outside of a cell, consisting of an RNA or DNA genome surrounded by a protein coat (capsid) and, for some viruses, a membranous envelope3
12780637856Chargaff's RuleChromosomes will contain equal amounts of adenine and thymine4
12780637857double helixThe structure of double stranded DNA.5
12780637858antiparallelThe two strands of DNA run in opposite directions (3' --> 5' / 5' --> 3')6
127806378602 hydrogen bondsadenine forms7
127806378613 hydrogen bondsguanine forms8
12780637863semiconservative modelType of DNA replication in which the replicated double helix consists of one old strand, derived from the parental molecule, and one newly made strand9
12780637864conservative modelthe two parental strands somehow come back together after the process10
12780637865dispersive modelall strands of DNA following replication have a mixture of old and new DNA11
12780637866origin of replicationSite where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides12
12780637867replication forkA Y-shaped region on a replicating DNA molecule where the parental strands are being unwound and new strands are being synthesized.13
12780637868helicaseAn enzyme that untwists the double helix of DNA at replication forks, separating the two strands and making them available as template strands.14
12780637869single-strand binding proteinA protein that binds to the unpaired DNA strands during DNA replication, stabilizing them and holding them apart while they serve as templates for the synthesis of complementary strands of DNA15
12780637870topoisomeraseA protein that breaks, swivels, and rejoins DNA strands. During DNA replication, ________ helps to relieve strain in the double helix ahead of the replication fork16
12780637871primerA short stretch of RNA with a free 3' end, bound by complementary base pairing to the template strand and elongated with DNA nucleotides during DNA replication17
12780637872primaseAn enzyme that joins RNA nucleotides to make a primer during DNA replication, using the parental DNA strand as a template18
12780637873DNA polymerase IIIAn enzyme that catalyzes the addition of a nucleotide to a free 3' carbon on another nucleotide.19
12780637875nucleoside triphosphatea nucleoside (a sugar and base) with three phosphate groups. where each added nucleotide comes from20
12780637876leading strandThe new complementary DNA strand synthesized continuously along the template strand toward the replication fork in the mandatory 5' --> 3' direction21
12780637877lagging strandA discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5' --> 3' direction away from the replication fork22
12780637878okazaki fragmentA short segment of DNA synthesized away from the replication fork on a template strand during DNA replication. Many such segments are joined together to make up the lagging strand of newly synthesized DNA.23
12780637881DNA polymerase IReplaces RNA primer nucleotides with DNA nuceleotides24
12780637882DNA ligaseA linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3' end of one DNA fragment (such as an Okazaki fragment) to the 5' end of another DNA fragment (such as a growing DNA chain)25
12780637885mismatch repairThe cellular process that uses specific enzymes to remove and replace incorrectly paired nucleotides26
12780637886nucleaseAn enzyme that cuts DNA or RNA, either removing one or a few bases or hydrolyzing the DNA or RNA completely into its component nucleotides27
12780637887nucleotide excision repairA repair system that removes and then correctly replaces a damaged segment (usually DNA pol I) of DNA using the undamaged strand as a guide28
12780637888thymine dimersthe covalent linking of thymine bases that are adjacent on a DNA strand. causes the DNA to buckle and interfere with DNA replication29
12780637889telomeresRepetitive DNA at the end of a eukaryotic chromosome's DNA molecule. ________ protect the organism's genes from being eroded during successive rounds of replication. repeating TTAGGG sequence between 100 and 1000 times30
12780637890telomeraseAn enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells31
12780637892histonesProteins which DNA is coiled around to form a nucleosome32
12780637894nucleosomeDNA coiled around histone proteins =33
12780637896histone tailthe amino end that extends outwards from each histone34
12780637903chromatinCondensed strands of nucleosomes. Wraps up further into chromosomes35
12780637904heterochromatinEukaryotic chromatin that remains highly compacted during interphase and is generally not transcribed36
12780637905euchromatinThe less condensed form of eukaryotic chromatin that is more available for transcription37
12780637910phosphodiester bondbond between the phosphate & the sugar in DNA or RNA38
12780902532Griffith's experimentDiscovered that bacteria can incorporated external DNA into their genomes. Was attempting to make a vaccine for pneumonia39
12780913707Avery Oswald ExperimentDiscovered that DNA was the transformative agent in Griffith's experiment by using enzymes to degrade the other possible components and then checking for transformation40
12780921066Hersey and ChaseUsed radioactive markers and viruses to determine that DNA was the transformative agent in bacteria, not proteins41
12780948312Meselson-Stahl ExperimentUsed different isotopes of nitrogen to change the weight of DNA. Demonstrated that the semi-conservative model is the best description of replication.42
12780958857VirulentDisease causing43
12780961886Non-virulentDoes not cause disease44

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