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AP Biology Chapter 18 Flashcards

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8348186354Operator-off/on "switch" that controls whole cluster of functionally related genes0
8348186355Operon-operate + promoter + genes they control -entire stretch of DNA for enzyme production for tryptophan pathway1
8348186356Repressor-protein that switches operon off2
8348186357Regulatory Gene (trpR)-product of trp repressor3
8348186358Corepressorsmall molecule that cooperates w/ repressor protein to switch operon off4
8348186359Repressible Operontranscription usually on but can be inhibited when specific small molecule binds allosterically to regulatory protein5
8348186360Inducible Operontranscription usually off but can be stimulated when specific small molecule interacts w/ regulatory protein6
8348186361Inducerspecific small molecule, inactivates repressor7
8348186363Activatorprotein that binds to DNA and stimulates gene transcription (ex. CAP)8
8348186364Differential Gene Expressionexpression of different genes by cells in the same genome9
8348186365Histone Acetylation-attached to lysines in histone tails -> lysines acetylated -> positive charges neutralized -histone tails no longer bind to neighboring nucleosomes10
8348186369Control Elementssegments of noncoding DNA that help regulate transcription by binding certain proteins11
8348186370Enhancers-distal control elements -may be thousands of nucleotides upstream/downstream of gene or in intron12
8348186372Alternative RNA Splicing-different mRNA molecules produced from same primary transcript, depending on which RNA segments are treated as introns and exons -can expand repertoire of eukaryotic genome13
8348186373Proteasomegiant protein complex recognize ubiquitin-tagged proteins and degradation14
8348186374microRNAs (miRNAs)-small, single-stranded RNA molecules capable of binding to complementary sequences in mRNA molecules15
8348186375RNA interference (RNAi)injecting double-stranded RNA molecules into cell turned off expression of gene w/ same sequence as RNA16
8348186376Small Interfering RNAs (siRNAs)-similar in size and function to miRNAs -formed by much longer double-stranded RnA molecules -> many siRNAs17
8348186377Cell Differentiationprocess by which cells become specialized in structure and function18
8348186378Morphogenesisphysical processes that give organism its shape19
8348186379Cytoplasmic Determinantsmaternal substances in egg that influence course of early development20
8348186380Inductionchanges in target cells caused by signals impinging on embryonic cell from others in vicinity, including contact w/ cell surface molecules on neighboring cells and binding of growth factors secreted by neighboring cells21
8348186381Determination-events that lead to observable differentiation of cell22
8348186384Homoeotic Genescontrol pattern formation in late embryo, larva, and adult23
8348186387Bicoid (two-tailed)-mutant gene causes lack of front half of body and posterior structure at both ends -essential for setting anterior end24
8348186388Morphagengradients for substances that establish embryos axis and more25
8348186389Oncogenes-cancer-causing genes26
8348186390Proto-Oncogenes-normal versions of cellular genes -code for proteins that stimulate normal cell growth and division27
8348186391Tumor-Supressor Genes-prevent uncontrolled cell growth -repair damaged DNA -control cell anchorage (absent in cancers)28
8348186393Ras ProteinG protein that relays signal from growth factor on plasma membrane29
8348186395p53tumor suppressor gene that codes for specific transcription factor protein that promotes synthesis of cell cycle30
8348186396Mutation Effects-result in cell cycle overstimulated -not inhibited normally31

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