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Ap Biology Chapter 43 Flashcards

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5064918971Innate immunityPresent before any exposure to pathogens and is effective from the time of birth (nonspecific responses, external barriers, and cellular/chemical defenses)0
5064930580Acquired immunityDevelops after expose to agents such as microbes, toxins, or other foreign substances1
5064938461Humoral resoponsePathogens in lymph (B lymphocytes or B cells are used)2
5064960352Cell mediatedPathogens in cells (uses Cytotoxic lymphocytes)3
5064966826BarriersStructures that prevent the intrusion of foreign substances and pathogens ( Mucus membranes and the acidity of skin)4
5064976061Patrolling cellsWhite blood cells5
5064978097Nitric axideDegrades microbes in lysosomes6
5064984496NeutrophilsEngulf and destroy microbes in infected tissues7
5064987030MacrophagesAre part of the lymphatic system and are found throughout the body8
5064990709EosinophilsDischarge destructive enzymes (don't ingest)9
5064995705Dendritic cellsEngulf microbes and carries a portion of the pathogen back to the spleen and lymph nodes to stimulate the development of acquired immunity10
5065009857Complement proteinsSearch for microbes, kill microbes, coats intruders, attracts macrophages, and causes inflamation11
5065017057InterferonProteins provide innate defense against viruses and help activate macrophages12
5065023508Mast cellsRelease histamine when you get injured13
5065026062HistaminePromotes changes in blood vessels to supply more blood14
5065029920FeverInhibits bacterial growth, stimulates phagocytosis, speeds up repair of tissues, and causes the liver and spleen to store iron15
5065040075Natural killersAttacks damaged cells by releasing chemicals that lead to the death of the cell by apoptosis16
5065046361AntigensForeign molecules or bad cells17
5065058623CytokinesSecreted by macrophages and dendritic cells to recruit and activate lymphocytes18
5065069089Membrane receptorsB and T cells use these to find antigens19
5065071991EpitopesBumps on antigens that B and T cells recognize20
5065081747Antigen receptorsB and T cells have roughly 100,000 of these21
5065085636Plasma cellsCreates antibodies which are antigen receptors22
5065093545Cell mediated immune responseInvolves activation and clonal selection of cytotoxic T cells23
5065098259Humoral mediated immune responseInvolves activation and clonal selection of B-cells resulting in the production of secreted antibodies24
5065108324MHC 1'sFound on almost all nucleated cells, they display peptide antigens to cytotoxic T cells25
5065124044MHC 2'sMainly on dendritic cells, macrophages, and B-cells which are antigen presenting cells that display antigens to cytotoxic T-cells and helper T-cells26
5065051031T-cellsAttack, learn, and remembers pathogens that hide in infected cells, matures in the thymus (helper T-cells, Cytotoxic T-cells, and Memory T-cells)27
5065054451B-cellsAttack, learn, and remember pathogens that are circulationg in the blood and lymph, matures in bone marrow28
5065146637CD4A surface protein in helper T-cells that binds to MHC 2's29
5065171660CD8A surface protein that greatly enhances the interactions between a target cell and a cytotoxic T-cell30
5065191547NeutralizationOccurs when a pathogen can no longer infect a host because it is bound to an antibody31
5065200054OpsonizationOccurs when antibodies bound to antigens increase phagocytosis32
5065206097Membrane attack complexAntibodies together with proteins of the complement system generate this and cell lysis33
5065222063Clonal selectionThe binding of a mature B or T lymphocyte to an anitgen induces the lymphocyte to divide rapidly34
5065235462Primary immune responseThe first exposure to a specific antigen during which B-cells called plasma cells are generated, and T-cells are activated35
5065237400Secondary immune responseMemory cells facilitate a faster, more efficient response36
5065278801Active immunityDevelops naturally in response to an infection due to B and T lymphocytes and the resulting memory cells (this can develop following a immunization)37
5065298730Passive immunityProvides immediate, short-term protection (weeks or months) and it is conferred naturally when IgG crosses the placenta from mother to fetus or when IgA passes from mother to infant in breast milk38
5065334984Organ/blood rejectionHappens when MHC tissue does not match39
5065350043Rh+ antibodiesAn antibody that can cross the placenta and can attack fetuses if the fetus is Rh-40
5065360157AllergensAntigens that cause exaggerated responses (allergies)41
5065369579AntihistaminesDecrease allergy symptoms by blocking histamine receptors42
5065388935Autoimmune diseasesThe immune system loses tolerance for self and turns against certain molecules of the body43
5065408179ImmunodeficiencyResults from hereditary or developmental defects that prevent proper functioning of innate, humoral, and/or cell-mediated defenses44
5065417342Acquired immunodeficiency syndrome (AIDS)Is caused by a virus45

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