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AP Biology : Chapter 45 : The Endocrine System Flashcards

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9602045650HormoneType of molecule that is secreted into extracellular fluid, circulates the blood/hemolymph, and communicates regulatory messages throughout the body0
9602045651Peptide v steroidcompound of amino acids -water soluble; can't pass through plasma membrane 1. secreted by exocytosis, travel freely in bloodstream 2. bind to cell surface receptors that give info to nucleus through intracellular pathways versus lipids with 4 rings of carbon atoms, derived from the steroid cholesterol -lipid soluble; pass through membrane -receptors for lipid soluble hormones are usually in nucleus/cytoplasm 1. diffuse across membranes 2. bind to transport proteins outside the cell, travel through bloodstream 3. diffuse into target cells and bind to receptors1
9602045652Blood glucose feedback loopInvolves Insulin (triggers uptake of glucose from blood into body cells) and glucagon (release glucose into blood from energy stores) -Both are produced in pancreas -If blood glucose increases: 1) beta cells in pancreas release insulin in blood 2) liver takes glucose and stores as glycogen 3) glucose level declines -If decreases: 1) alpha cells of pancreas release glucagon into blood 2) liver breaks down glycogen and release glucose into blood 3) glucose level increases2
9602045653HypothalamusReceives info from nerves throughout the body and in response, initiates endocrine signaling appropriate to env'tal conditions -hormones released from posterior pituitary and hormones regulate anterior pituitary3
9602045654Blood calcium feedback loopFalling blood Ca2+ level -Parathyroid glands release parathyroid hormone (PTH) -Increased Ca2+ uptake in kidneys -Increased Ca2+ uptake in intestines -Stimulates Ca2+ release from bones Rising blood Ca2+ level -Thyroid gland releases calcitonin -Stimulates Ca2+ deposition in bones -Reduces Ca2+ uptake in intestines -Reduces Ca2+ uptake in kidneys4
9602045655EcdysteroidA steroid hormone that triggers the growth of adult cells/death of larval cells in insects5
9602045656Endocrine systemA group of glands that secrete chemicals into the bloodstream that help control bodily functioning -Hormones secreted can regulate reproduction, energy, development, growth, metabolism, and behavior6
9602045657Endocrine signalingSecreted molecules diffuse into the bloodstream and trigger responses in target cells anywhere in the body -maintains homeostasis -responses to env't -regulates growth/development -physical/behavioral changes7
9602045658Local regulatorsMolecules that act over short distances. Reach target cells only by diffusion (messengers)8
9602045659Paracrine signalingTarget cells are near the secreting cell9
9602045660Autocrine signalingThe target cell is the secreting cell (molecules diffuse locally and trigger responses in the secreting cell)10
9602045661Synaptic signallingNeurotransmitters diffuse across synapses and trigger responses in the cells of target tissues (neurons, muscles, glands)11
9602045662Neuroendocrine signalingNeurohormones diffuse into the bloodstream and trigger responses in target cells anywhere in the body12
9602045663NeurotransmittersMolecules secreted by neurons at synapses -Diffuse short distances to bind to receptors on target cell -sensation, memory, cognition, movement13
9602045664NeurohormonesChemicals released by neurons into the blood for action at distant targets14
9602045665PheromonesChemicals released into external env't -attraction, warning (predators), forming territories15
9602045666Signal transductionSeries of changes in cellular proteins that converts the extracellular chemical signal to a specific intracellular response16
9602045667EpinephrineAdrenaline -Binds to a G protein coupled receptor (once it reaches the liver) in the plasma membrane of target cells -Binding triggers synthesis of cAMP as a second messenger -Protein kinase A activated by cAMP -enzyme becomes activated for glycogen sysnthesis -liver releases glucose in bloodstream17
9602045668Growth factorsStimulate the growth and division of cells18
9602045669Nitric oxideFunctions as both a neurotransmitter and local regulator19
9602045670Negative/positive feedback loopsThe response decreases/reinforces a stimulus20
9602045671Growth hormone GHSecreted by the anterior pituitary gland -stimulates growth through tropic and nontropic effects -liver responds by releasing insulin like growth factors, which circulate blood and stimulate bone/cartilage growth -skeleton of immature animal stops growing when it isn't there -raises blood glucose levels (opposing insulin)21
9602045672NorepinephrineA neurotransmitter involved in arousal, as well as in learning and mood regulation22
9602045674Thyrotropin releasing hormone TRHHormone released by hypothalamus to activate TSH23
9602045675Thyroid stimulating hormone TSHCauses thyroid gland cells to secrete T3 and T4; stimulates thyroid growth24
9602045676Difference between endocrine and exocrine systemsEndocrine: glands secrete hormones directly into the surrounding fluid (within) Exocrine: glands have ducts that carry secreted substances onto body surfaces/cavities (out of)25
9602045677Difference between tropic and nontropic hormoneTropic: regulate the function of other endocrine cells/glands -TSH -ACTH -FSH -LH Nontropic: targets tissues that are not part of the endocrine system26
9602045678Difference between afferent and efferentAfferent: towards something (nerves=central nervous system, blood=heart) Efferent: conducting away from something27
9602045679Posterior pituitary glandReleases neurohormones made in hypothalamus (extension of hypothalamus) -Hormones: ADH (promotes retention of water by kidneys) and Oxytocin (contraction of uterus/mammary gland cells) -Peptide28
9602045680Anterior pituitary glandSynthesizes and secretes hormones in response to signals from the hypothalamus -Hormones: GH (stimulates bone growth/metabolic functions) -TSH (stimulates thyroid gland) -Prolactin (milk production and secretion)29
9602045681Thyroid glandRegulates metabolism -T3 and T4 (stimulate and maintain metabolic processes) -Calcitonin (lowers blood calcium) As thyroid hormones accumulate, it increases metabolic rate, releasing thermal energy and increasing body temp30
9602045682Parathyroid glandsControl calcium and phosphorus metabolism; produce parathyroid hormone. -PTH raises blood calcium levels31
9602045683PancreasRegulates the level of sugar in the blood -Insulin (lowers blood glucose)- beta cells -Glucagon (increases blood glucose)- alpha -Exocrine gland that produces digestive enzymes32
9602045684Adrenal glandsAdrenal medulla -Epinephrine, norepinephrine (increase blood glucose and metabolic activities, constrict blood vessels) Adrenal cortex -Glucocorticoids (raise blood glucose), mineralocorticoids (promote reabsorption of sodium ions and excretion of potassium in kidneys)33
9602045685GonadsTestes Ovaries34
9602045686Pineal glandSecretes melatonin, involved in biological rhythms -Affected by light and dark cycles35

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