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AP Biology- Gene Regulation Flashcards

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6135281866operonconsist of a promoter, an operator, and a cluster of genes that control gene regulation in a common pathway, "on and off" switches0
6135281867repressible operonoperon that is normally on because the repressor is inactive1
6135281868inducible operonoperon that is normally off because the repressor is active2
6135281869structural genegenes to be expressed3
6135281870operatora segment of DNA in the promoter region that acts as an on or off "switch"4
6135281871repressora protein that binds to the operator to switch the operon off5
6135281872inducerinactivates the repressor (turns on the operon)6
6135281873regulatory genecodes for the production of the repressor protein and is found upstream of the operon7
6135281874corepressorworks with the repressor to turn off the operon8
6135281875catabolite activator protein (CAP)activator of transcription, binds to cAMP (cyclic adenosine monophosphate) when sugar is scarce which *increases the affinity of RNA polymerase and accelerates transcription of lactose*9
6135281876cellular differentiationthe formation of cells that are specialized in structure and function10
6135281877histone acetylationthe process of acetyl groups attaching to histone tails (opens up chromatin structure)11
6135281878DNA methylationadding a methyl group to cytosine bases during replication, associated with inactivation of genes and reduced transcription12
6135281879enhancergroups of distal control elements located upstream of downstream from a gene or within an intron13
6135281880activatora specific protein that binds to an enhancer to stimulate gene transcription14
6135281881transcription factorssome act as repressors by blocking the binding of activators or binding to an enhancer15
6135281882RNA interferencethe phenomenon of inhibition of gene expression by non-coding RNA molecules (a technique used to silence the expression of selected genes)16
6135281883RNA polymerasean enzyme that links ribonucleotides into a growing RNA chain during transcription17
6135281884miRNAa.k.a. microRNA, associates with one or more proteins in a complex that can degrade or prevent translation of an mRNA with a complementary sequence18
6135281885siRNAa.k.a. small interfering RNA, associates with one or more proteins in a complex that can degrade or prevent translation of an mRNA with a complementary sequence19
6135281886cytoplasmic determinantsa maternal substance that when placed into an egg influences the course of early development by regulating the expression of genes that affect the developmental fate of cells20
6135281887inductionthe process in which one group of embryonic cells influences the development of another, usually by causing changes in gene epression21
6135281888morphogenesisthe cellular and tissue based processes by which an animal body takes shape22
6135281889proto-oncogenea normal cellular gene that has the potential to become an oncogene23
6135281890ras genea gene that codes for Ras (a G protein that relays a growth signal from a growth factor receptor on the plasma membrane to a cascade of protein kinases) ultimately resulting in stimulation of the cell cycle24
6135281891tumor suppressor genea gene whose protein product inhibits cell division thereby preventing the uncontrolled cell growth that contributes to cancer25
6135281892p53 genea tumor suppressor gene that codes for a specific transcription factor that promotes the synthesis of proteins that inhibit the cell cycle26
6135281893negative feedbackinhibits expression27
6135281894positive feedbackactivates expression28
6135281895feedback inhibitionconcentration of substances present in cell either inhibit or activate expression29
6135281896cataboliclac operon30
6135281897anabolictrp operon31
6135281898heterochromatinharder transcription initiation32
6135281899epigeneticsthe field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism33
6135281900epigenomethe chemical compounds that modify or mark the DNA and change the way genes are expressed34
6135281901alternative DNA splicingproduces different mRNA molecules when different segments of the mRNA are chosen as introns or exons35
6135281902chromatin modificationpromotes the formation of heterochromatin in certain regions blocking transcription36
6135281903cell divisionthe production of large numbers of cells37
6135281904determinationthe condition in which a cell is irreversibly committed to its fate, even if it has not developed its final structure38
6135281905pattern formationthe development of a spatial organization of tissues and organs into their locations under the control of body plan genes39
6135281906positional informationmolecular cues provided by cytoplasmic determinants and inductive signals40
6135281907HOX genes (homeotic genes)primary genes responsible for head to toe formation41
6135281908oncogenescancer causing cells42
6135281909amplificationincreasing the number of copies of the gene43
6135281910tumor virusesviruses that insert their DNA into the host DNA near a proto-oncogene44
6135281911ectodermskin/nervous system45
6135281912mesodermmuscles46
6135281913endodermdigestive system47

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