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AP Biology Molecular Genetics Flashcards

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9280501729nucleotidesa nitrogenous base, a sugar, and a phosphate group0
9280501730PurineA/G, 2 organic rings, 2X the size, 2 hydrogen bonds1
9280501731PyrimidineC/T, single ring, X size, 3 hydrogen bonds2
9280501732origins of replicationThe site where replication occurs where the two DNA strands are separated, opening up a replication "bubble".3
9280501733DNA polymeraseadds nucleotides to the 3' end of the growing DNA sequence. It needs a primer. It can only go in one direction and extend on an existing DNA molecule4
9280501734RNA PrimaseIn DNA replication, this enzyme adds temporary RNA nucleotides for DNA polymerase to work from and add nucleotides to5
9280501735replication forka Y-shaped region where new DNA strands are elongating that is located at the end of the replication bubble.6
9280501736Helicaseenzyme that untwist the double helix at the replication forks.7
9280501737Topoisomeraseenzyme that corrects "overwinding" ahead of replication forks by breaking, swiveling, and rejoining DNA strands8
9280501738leading strandthe template strand of DNA where replication happens continuously toward the replication fork because it is aligned properly9
9280501739lagging strandthe template strand of DNA where DNA polymerase must work in the direction away from the replication fork. New DNA is created in fragments10
9280501740Okazaki fragmentsThe fragments that compose the lagging strand. (The spaces between the fragments are later filled via DNA ligase to make a continuous DNA strand.)11
9280501741Chromatina complex of DNA and protein, is found in the nucleus of eukaryotic cells. DNA is spread out (not coiled)12
9280501742Transcriptionthe synthesis of RNA using information in DNA13
9280501743Translationthe synthesis of a polypeptide, using information in the mRNA14
9280501744Codona group of three nucleotides that code for an amino acid15
9280501745Ribosomesthe sites of translation16
9280501746primary transcriptinitial RNA transcript from any gene prior to processing17
9280501747central dogmathe concept that cells are governed by a cellular chain of command: DNA to RNA to protein18
9280501748promoterThe DNA sequence where RNA polymerase attaches to start transcription.19
9280501749The three stages of transcriptionInitiation, Elongation, Termination20
9280501750transcription initiation complexThe completed assembly of transcription factors and RNA polymerase II bound to a promoter21
9280501751Transcription factorsMolecules that mediate the binding of RNA polymerase and the initiation of transcription22
9280501752intronsThe noncoding regions of mRNA that get removed during RNA processing23
9280501753RNA splicingremoves introns and joins exons, creating an mRNA molecule with a continuous coding sequence24
9280501754tRNAstransfer amino acids to the growing polypeptide in a ribosome25
9280501755anticodonthree nucleotides in the tRNA that pairs with a complementary codon on mRNA26
9280501756P siteholds the tRNA that carries the growing polypeptide chain27
9280501757alternative RNA splicingdifferent mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns28
9280501758exonspart of the pre-mRNA that is not removed - they are joined together to make the mRNA29

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