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AP Biology- Signal Transduction Flashcards

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11290555078Intracellular SignalsProteins located into the cytoplasm or nucleus that receive a signal that can pass through the cell membrane.0
11290570380Give an example and non- exampl of an intracellular signal.EX: Steroids (Hormones) Non-EX: Nitric Oxide1
11290583327TransductionCascades or molecular interactions that relay signals from receptors to target molecules in the cell.2
11290597877Transduction multi-step pathways can...1: Amplify a signal by activating multiple choices of the next component in the pathway. 2: Provide more opportunities for coordination and regulation.3
11290620595A each step in the transduction pathway, the signal is _______ into a different form, commonly known as a _______ in a protein.transduced; conformational change.4
11290626464Kinases canTurn on Processes5
11290634945Phosphatase canTurn off processes.6
11290638647Protein PhosphorylationHas many signal pathway including phosphorylation cascades.7
11290653439phosphorylation cascadesProcess in which a series of enzymes called protein kinases add a phosphate from ATP to a protein to the next one in line, activating it.8
11290669206DephosphoryationOccurs when phosphatase enzymes remove the phosphates from the protein.9
11290701719Benefits of multi-step transduction process (3)1: Amplify the response to the signal. 2: Contribute to the specificity of the response. 3: It is a rapid and reversible response.10
11290713903Secondary MessengersSmall, non-protein, water-soluble molecules or ions that pass a signal; spread via diffusion.11
11290725884Examples of Secondary Messengers (4)cAMP, GMP, Ca2+, IP2-12
11290729531cAMPA form of AMP made directly from ATP by adenylyl cyclase; short- lived, activates a number of protein kinases.13
11290748331Calcium IonsWhen released into the cytosol of a cell, it can regulate its concentration and used as a messenger in G-Protein and Tyrosine Kinase Receptor Pathways.14
11290775105Inositol Triphosphate (IP3-)Attached to phospholipids of a cell membrane and sent to calcium channel on the Endoplasmic Reticulum. Aids in flow of Calcium Ions into the cytoplasm from the ER.15
11290795385If liver and heart cells both are exposed to ligands, why does one respond and the other not?Different cells have different collections and locations of receptors.16
11290803348Specificity of the signal...The same signal molecule can trigger different responses, activators or inhibitors, and receptors.17
11290827802Response of Cell SignalingLeads to regulation of transcription or cytoplasmic activities.18
11290837349Gene ExpressionProcess which information from a gene is used by the cell to produce a functional product; involves transcription and translation. EX: Growth Factor19
11290846093TranscriptionMakes an RNA copy of the genes in DNA.20
11290849236TranslationReads the information from RNA and uses it to make a protein.21
11290857006Cellular MetabolismA metabolic response that can cause enzymes to become more or less active, EX: Epinephrine22
11290864594ApoptosisMay be induced by cell signaling; when a cell is damaged, unneeded, or potentially dangerous to the organism, it may undergo programmed cell death.23
11290883048Apoptosis allows a cell to die in a ____ manner that prevents the release of damaged molecules inside the cell.Controlled24
11290887308Termination of the signalSignal response is terminated quickly by the reversal of the ligand binding.25

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