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10942018207immunityResistance to disease0
11056464450non-specific defense systemresponds immediately to protect the body from all foreign substances1
11056468631specific (adaptive) defensesemploy activated lymphocytes to mount the immune response to specific threats2
11056471718Pathogensdisease causing agents3
11056474467First line of defenseintact skin, mucous membranes and their secretions, normal microbiota4
11056479347Second line of defense (innate immunity)-phagocytes, such as neutrophils, eosinophils, dendritic cells, and macrophages -inflammation -fever -antimicrobial substances5
11056481423third line of defense (specific)Production of specific antibodies or cell-mediated immunity6
11056483772MacrophagesFound within the lymph nodes, they are phagocytes that destroy bacteria, cancer cells, and other foreign matter in the lymphatic stream.7
11056486459MonocytesAn agranular leukocyte that is able to migrate into tissues and transform into a macrophage.8
11056487891neutrophilsA type of white blood cell that engulfs invading microbes and contributes to the nonspecific defenses of the body against disease.9
11056491010OpsonizationAn immune response in which the binding of antibodies to the surface of a microbe facilitates phagocytosis of the the microbe by a macrophage10
11056491011natural killer cells (NK cells)pursue diseased cells (such as those infected by viruses or cancer)11
11056499216inflammationa localized response to an injury or to the destruction of tissues12
11056501670Complementenhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.13
11056506524Antimicrobial proteinsProteins that inhibit microbial reproduction and provide short-term, nonspecific resistance to pathogenic bacteria and viruses14
11056509649InterferonsAntiviral proteins secreted by T cells15
11056511441Lysozymean enzyme found in saliva and sweat and tears that destroys the cell walls of certain bacteria16
11056512777Feverelevated body temperature17
11056515402Humoral immunity or antibody-mediated immunityB cells provide a defense against antigens and pathogens in body fluids18
11056516344Cellular or cell-mediated immunityT- cells do the killing of the cells19
11056518153Antigensforeign substances that trigger the attack of antibodies in the immune response.20
11056518154Antigenic determinantthe specific area of an antigen that binds with an antibody combining site and determines the specificity of the antigen-antibody reaction21
11056520554T lymphocytesform in the thymus and other lymphatic tissue and attack cancer cells, viruses, and foreign substances22
11056520555B lymphocytes (B cells)Lymphocyte that matures in the bone marrow and secretes antibodies.23
11056523869clonemember of a population of genetically identical cells produced from a single cell24
11056525527Clonal selectionThe process by which an antigen selectively binds to and activates only those lymphocytes bearing receptors specific for the antigen. The selected lymphocytes proliferate and differentiate into a clone of effector cells and a clone of memory cells specific for the stimulating antigen.25
11056528742Immuglobin- Antibodies - part of specific immune system - Binds to pathogens (can be bad e.g. virus)26
11056531293antigen binding siteThe site on an immunoglobulin or T-cell receptor molecule that binds specific antigen.27
11056533364antibody classes (isotypes)isotypes28
11056538665Antigen-antibody complexesimmobilize the antigens until certain immune cells can break them down29
11056541976neutralizationantibody (NAb) is an antibody that defends a cell from an antigen or infectious body by neutralizing any effect it has biologically. An example of a neutralizing antibody is diphtheria antitoxin, which can neutralize the biological effects of diphtheria toxin.30
11056550626AgglutinationClumping of microorganisms or blood cells, typically due to an antigen-antibody interaction.31
11056552550Precipitationsweating32
11056555776Complement fixation and activationMain antibody defense against cellular antigens, several antibodies bind close together on a cellular antigen, their complement-binding sites trigger complement fixation into the cell's surface, complement triggers cell lysis, activated complement functions, amplifies the inflammatory response, opsonization, and enlists more and more defensive elements.33
11056557681Cell mediated immune responseThe branch of acquired immunity that involves the activation of cytotoxic T cells, which defend against infected cells.34
11056560082Helper T cellsT cells that help the immune system by increasing the activity of killer cells and stimulating the suppressor T cells35
11056560083Cytotoxic T cellsA type of lymphocyte that kills infected body cells and cancer cells36
11056562772Regulatory T cellscontrol the T-cell response37

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