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Bio Ch 19 Viruses Flashcards

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3413496231Enveloped Virusgenerally escape from the host cell by budding. Because of this, the viral envelope is often derived from the host cell's plasma membrane -phospholipid membrane outside the capsid0
3413496232Nonenveloped Virustypically exit the host cell by bursting through the plasma membrane -lack phospholipid membrane1
3413498261HIVHuman immunodeficiency virus (HIV) is a retrovirus that contains two copies of single-stranded RNA genome and two copies of reverse transcriptase. The HIV viral envelope facilitates binding to a white blood cell. After HIV enters the cell, the reverse transcriptase synthesizes viral DNA from viral RNA.2
3413582580ProvirusViral DNA that has become part of the host's genome3
3413610361Vaccines-most effective in treating infections -Function: stimulate the immune system to defend against the potential pathogen4
3417162810Who is susceptible to viral infections?Anything that is capable of replicating itself aka EVERYTHING5
3417175294First virus ever discoveredtobacco mosaic virus -late 1800s - 1935 Stanley confirmed virus thru crystallization6
3417180312bacterophageinfect bacteria7
3417188978How are viruses classified?capsid shape, envelope presence, nuceic acid (either RNA or DNA, double or single stranded), how they reproduce8
3417356814Capsid vs envelopeAll viruses have capsid Not all have envelope envelope- outer most layer of protein9
3417362436Capsidprotective shell made of proteins (capsomeres) *determines shape of virus 3 types: helical > rod-shaped isosahedral > complex (doesn't fit other categories)10
3417390459Envelope-not all viruses have this -composed of lipid (from prior host) and proteins11
3435001212What defines the virus in terms of the genomeonly has genes that help invade and regulate metabolic activity of the host cells note: viruses can't generate their own energy12
3435073831Why do single stranded RNA viruses mutate easily?There is nothing to check their replication so if theere is a mistake there is no way to check it13
3435083149Virus Replication CycleAbsorption, Penetration, Uncoating (releases genome into cell), Synthesis , Assembly, Release14
3435113621Animal Replication CycleAbsorption, Synthesis 1, Synthesis 2, Assembly &Release15
3435125751The host range of a virus is determined by:the proteins on its surface and that of the host16
3435151606Animal Cell Retrovirus replication cycle17
3435153039BacteriophagesBacterial viruses18
3435170079Lytic Cycle (Virulent phage)-DNA replicated and bacterium killed -single bacterial cell produces hundreds of viruses -19
3435175014Lysogenic Cycle (Prophage)-Viral DNA inserted into host DNA -bacterium survives and viral DNA copied when bacterium divides -stress can change the cell into the lytic cycle20
3435214421What is the term of a bacteriophage that has become integrated into the host cell chromosome?Prophage21
3435224409What is the biggest difference between enveloped and naked virus in the stages of replication in animals?Release22
3435244210What stage of animal viral replication cycle differs the most between DNA and RNA viruses?Synthesis23
3435251802Important Viral Diseases in HumansAIDS/HIV, chickepox, influenza, meales, Hepatitis, Herpes, Mumps, Pneumonis, Rabies, Yellow Fever, Polio, Ebola, Small pox -when viruses infect the host cell their capsules may be poisonous to host24
3435265615What happened in 1918?Pandemic influenza virus -deadliest in human history -40 million died worldwide -variablity and mutations make it difficult to treat -Hemagglutinin -Neuraminidase25
3435296829Emerging Virushigh rate of mutation previously nonpathogenic virus becomes bad HIV in 1980s West Nile 199926
3435314546AIDS/HIV-spread by fluids & intimate contact -targets immune system cells27
3435332484Prions-protein particle with no nucleic acid or capsid - can be in body for a long time (long latency period)28
3443748153Virus Living or nonliving?-infectious particle consisting of genes and protein coat -nonliving because cannot reproduce (more like "borrowed life")29
3553942889Viral envelopes-derived from membrane of host cell30
3553952187host range of a virus-limited number of host cells that a particular virus can infect31
3553983592virulent phagephage that replicates only by lytic cycle32
3553988845restriction enzymes-activity restricts phage from replicating within bacterium -marks the cell as foreign and cuts it up33
3554012230lysogenic cycle-phage replicates inside the cell without destroying it -viral DNA incorporated into host DNA34
3554024958temperate phagesphages that use the lytic and lysogenic cycles for replication35
3554041307prophageviral DNA that is integrated into host bacterium DNA & ejected from host DNA when enter lytic cycle36
3554091460retroviruses-reverse transcriptase -HIV & AIDS37
3554097039reverse transcriptaseenzyme that transcribes RNA template into DNA38
3554117382HIV-enveloped virus with single-stranded RNA and reverse transcriptase -viral DNA inserted into host cell39
3554134036provirus-viral DNA integrated into host DNA that never leaves host genome40
3554476188epidemicwidespread outbreak41
3554478006pandemicglobal epidemic42
3554487492viroids-infectious nucleic acid -circular RNA strands that infect plants -do not encode proteins -affect plant growth (sx: stunted growth)43
3554504333prions-infectious proteins with very long incubation period -infect animals -ex: scrapie, mad cow disease, Creutzfeldt-Jakob Disease44

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