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Campbell Biology 7th Edition: Chapter 10 - Molecular Biology of the Gene Flashcards

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1886066491Molecular biologyThe study of heredity at the molecular level0
1886066492BacteriophagesA virus that infects bacteria; also called a phage.1
1886066493NucleotidesBasic units of DNA molecule, composed of a sugar, a phosphate, and one of 4 DNA bases2
1886066494PolynucleotideA polymer made up of many nucleotides covalently bonded together3
1886066495Sugar-phosphate backboneThe alternating chain of sugar and phosphate to which the DNA and RNA nitrogenous bases are attached4
1886066496DNA(deoxyribonucleic acid) a complex molecule containing the genetic information that makes up the chromosomes.5
1886066497ThymineA component of nucleic acid that carries hereditary information in DNA in cells. Chemically, it is a pyrimidine base.6
1886066498CytosineA component of nucleic acids that carries hereditary information in DNA and RNA in cells. Chemically, it is a pyrimidine base.7
1886066499AdenineA component of nucleic acids, energy-carrying molecules such as ATP, and certain coenzymes. Chemically, it is a purine base.8
1886066500GuanineA component of nucleic acids that carries hereditary information in DNA and RNA in cells. Chemically, it is a purine base.9
1886066501UracilA nitrogen-containing base found in RNA (but not in DNA) and derived from pyrimidine10
1886066502Double helixThe form of native DNA, referring to its two adjacent polynucleotide strands wound into a spiral shape.11
1886066503Semiconservative modelType of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand. Watson and Crick's model.12
1886066504Origins of replicationSites where the replication of a DNA molecule begins.13
1886066505DNA polymerasesEnzyme that link DNA nucleotides to a growing daughter strand. Add nucleotides to the 3' end and never to the 5' end.14
1886066506DNA ligaseA linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3' end of a new DNA fragment to the 5' end of a growing chain.15
1886066507TranscriptionThe organic process whereby the DNA sequence in a gene is copied into mRNA16
1886066508TranslationThe process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm17
1886066509Triplet codeA set of three-nucleotide-long words that specify the amino acids for polypeptide chains18
1886066510CodonsA three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code.19
1886066511Genetic codeA set of rules that defines how the four-letter code of DNA is translated into the 20-letter code of amino acids, which are the building blocks of proteins.20
1886066512RNA polymeraseAn enzyme that links together the growing chain of RNA nucleotides during transcription, using a DNA strand as a template.21
1886066513TerminatorA special sequence of nucleotides in DNA that marks the end of a gene. It signals RNA polymerase to release the newly made RNA molecule, which then departs from the gene22
1886066514Messenger RNA(mRNA) RNA molecule that carries copies of instructions for the assembly of amino acids into proteins from DNA to the rest of the cell23
1886066515IntronsA noncoding, intervening sequence within a eukaryotic gene.24
1886066516ExonsA coding region of a eukaryotic gene. Exons, which are expressed, are separated from each other by introns.25
1886066517RNA splicingProcess by which introns are removed and exons are joined together.26
1886066518Transfer RNA(tRNA) Converts the words of codons to the amino acid words of proteins27
1886066519AnticodonA specialized base triplet at one end of a tRNA molecule that recognizes a particular complementary codon on an mRNA molecule.28
1886066520RibosomesCytoplasmic organelles at which proteins are synthesized.29
1886066521Ribosomal RNA(rRNA) The most abundant type of RNA, which together with proteins, forms the structure of ribosomes. Ribosomes coordinate the sequential coupling of tRNA molecules to mRNA codons.30
1886066522Start codonA specific codon (AUG) that signals to the ribosome that the translation commences at that point31
1886066523Codon recognitionthe anticodon of an incoming tRNA molecule, carrying its amino acid, pairs with the mRNA codon in the A site of the ribosome32
1886066524Peptide bond formationThe polypeptide separates from the tRNA to which it was bound and attaches to a peptide bond to the aminno acid carried by the rRNA in the A site.33
1886066525TranslocationChange to a chromosome in which a fragment of one chromosome attaches to a nonhomologous chromosome34
1886066526Stop codonUAG, UAA, or UGA; the codon that ends all RNA.35
1886066527MutationA change in the nucleotide-base sequence of a gene or DNA molecule36
1886066528Silent mutationA mutation that changes the codon triplet of nucleotides; however, the codon still codes for the same protein as before the mutation.37
1886066529Missense mutationA point mutation in which a codon that specifies an amino acid is mutated into a codon that specifies a different amino acid.38
1886066530Nonsense mutationA mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein.39
1886066531Reading frameThe way a cell's mRNA-translating machinery groups the mRNA nucleotides into codons40
1886066532MutagenesisThe creation of a change in the nucleotide sequence of an organism's DNA.41
1886066533MutagensA chemical or physical agent that interacts with DNA and causes a mutation.42
1886066534VirusA piece of code that is capable of copying itself and typically has a detrimental effect, such as corrupting the system or destroying data.43
1886066535CapsidOuter protein coat of a virus44
1886066536Lytic cycleA viral reproductive cycle in which copies of a virus are made within a host cell, which then bursts open, releasing new viruses45
1886066537Lysogenic cycleA viral reproductive cycle in which the viral DNA is added to the host cell's DNA and is copied along with the host cell's DNA46
1886066538ProphageThe viral DNA that is embedded in the host cell's DNA47
1886066539Emerging virusesA virus that has appeared suddenly or has recently come to the attention of medical scientists48
1886066540AIDS(Acquired Immune Deficiency Syndrome) a syndrome caused by the human immunodeficiency virus (HIV) that renders immune cells ineffective, permitting opportunistic infections, malignancies, and neurologic diseases to develop; transmitted sexually or through contaminated blood49
1886066541HIVHuman Immunodeficiency Virus50
1886066542Reverse transcriptaseAn enzyme encoded by some certain viruses (retroviruses) that uses RNA as a template for DNA synthesis.51
1886066543RetrovirusesAn RNA virus tha treplicates by transcribing its RNA into DNA and then inserting the DNA into a cellular chromosome.52
1886066544ViroidsCircular RNA molecules that infect plants and disrupt their growth53
1886066545PrionsInfectious proteins responsible for several fatal neurodegenerative diseases in humans and other animals.54
1886066546TransformationModification of a cell or bacterium by the uptake and incorporation of exogenous DNA55
1886066547TransductionThe process of transfering genetic material from one cell to another by a plasmid or bacteriophage56
1886066548ConjunctionUnion of two bacterial cell, this is the DNA transfer between them57
1886066549F FactorA fertility factor in bacteria; a DNA segment that confers the ability to form pili for conjugation and associated functions required for the transfer of DNA from donor to recipient. It may exist as a plasmid or be integrated into the bacterial chromosome.58
1886066550PlasmidA small ring of DNA that carries accessory genes separate from those of the bacterial chromosome59
1886066551R plasmidsA bacterial plasmid carrying genes that confer resistance to certain antibiotics.60

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