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Campbell Biology Chapter 17- AP Flashcards

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8257052550A Siteone of a ribosome's three binding sites for tRNA during translation; the A site holds the tRNA carrying the next amino acid to be added to the polypeptide chain. (A stands for aminoacyl tRNA.)0
8257052551Alternative RNA Splicinga type of eukaryotic gene regulation at the RNA-processing level in which different mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns1
8257052552Anticodona nucleotide triplet at one end of a tRNA molecule that base-pairs with a particular complementary codon on an mRNA molecule2
8257052553Codona three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code3
8257052554Exona sequence within a primary transcript that remains in the RNA after RNA processing; also refers to the region of DNA from which this sequence was transcribed4
8257052555Frameshift MutationA mutation occurring when nucleotides are inserted in or deleted from a gene and the number inserted or deleted is not a multiple of three, resulting in the improper grouping of the subsequent nucleotides into codons5
8257052556Gene Expressionthe process by which information encoded in DNA directs the synthesis of proteins or, in some cases, RNAs that are not translated into proteins and instead function as RNAs6
8257052557Insertiona mutation involving the addition of one or more nucleotide pairs to a gene7
8257052558Introna noncoding, intervening sequence within a primary transcript that is removed from the transcript during RNA processing; also refers to the region of DNA from which this sequence was transcribed8
8257052559Messenger RNA (mRNA)a type of RNA, synthesized using a DNA template, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein. (In eukaryotes, the primary RNA transcript must undergo RNA processing to become mRNA.)9
8257052560Missense Mutationa nucleotide-pair substitution that results in a codon that codes for a different amino acid10
8257052561Mutagena chemical or physical agent that interacts with DNA and can cause a mutation (Ex: UV light, tanning bed)11
8257052562Mutationa change in the nucleotide sequence of an organism's DNA or in the DNA or RNA of a virus12
8257052563Nonsense Mutationa mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein13
8257052564Substitutiona type of point mutation in which one nucleotide in a DNA strand and its partner in the complementary strand are replaced by another pair of nucleotides14
8257052565P Siteone of a ribosome's three binding sites for tRNA during translation; the P site holds the tRNA carrying the growing polypeptide chain. (P stands for peptidyl tRNA.)15
8257052566Point Mutationa change in a single nucleotide pair of a gene16
8257052567Poly-A Taila sequence of 50-250 adenine nucleotides added onto the 3′ end of a pre-mRNA molecule17
8257052569Primary Transcriptan initial RNA transcript from any gene; also called pre-mRNA when transcribed from a protein-coding gene. This is what you get right after the slicing occurs.18
8257052570Reading Frameon an mRNA, the triplet grouping of ribonucleotides used by the translation machinery during polypeptide synthesis19
8257052571Ribosomal RNA (rRNA)RNA molecules that, together with proteins, make up ribosomes; the most abundant type of RNA20
8257052572Ribosomea complex of rRNA and protein molecules that functions as a site of protein synthesis in the cytoplasm; consists of a large and a small subunit. In eukaryotic cells, each subunit is assembled in the nucleolus; see also nucleolus21
8257052573RNA Processingmodification of RNA primary transcripts, including splicing out of introns, joining together of exons, and alteration of the 5′ and 3′ ends22
8257052574RNA Splicingafter synthesis of a eukaryotic primary RNA transcript, the removal of portions of the transcript (introns) that will not be included in the mRNA and the joining together of the remaining portions (exons)23
8257052575Silent Mutationa nucleotide-pair substitution that has no observable effect on the phenotype; for example, within a gene, a mutation that results in a codon that codes for the same amino acid24
8257052576TATA Boxa DNA sequence in eukaryotic promoters crucial in forming the transcription initiation complex25
8257052577Template Strandthe DNA strand that provides the pattern, or template, for ordering, by complementary base pairing, the sequence of nucleotides in an RNA transcript26
8257052578Transcriptionthe synthesis of RNA using a DNA27
8257052579Transfer RNA (tRNA)an RNA molecule that functions as a translator between nucleic acid and protein languages by carrying specific amino acids to the ribosome, where they recognize the appropriate codons in the mRNA28
8257052580TranslationThe synthesis of a polypeptide using the genetic information encoded in an mRNA molecule; there is a change of "language" from nucleotides to amino acids29
8257052581Triplet Codea genetic information system in which sets of three-nucleotide-long words specify the amino acids for polypeptide chains30
8257052582Wobbleflexibility in the base-pairing rules in which the nucleotide at the 5′ end of a tRNA anticodon can form hydrogen bonds with more than one kind of base in the third position (3′ end) of a codon31
8363982307Silent mutationsusually found in noncoding regions of DNA32

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