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cH.5 CELLULAR MOLECULES AND MACROMOLECULES Flashcards

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6766129917Cellular MacromoleculesAll living things are made up of 3 classes of large biological molecules: carbohydrates, lipids, proteins, and nucleic acids0
6766141590Lipids vs otherAll but lipids are polymers1
6766148640Polymera long molecule consisting of many similar building blocks2
6766153129Monomerthe repeating units that serve as building blocks3
6766160887Polymers- Carbohydrates (Polysaccharide)Monomers- Monosaccharides4
6766167616Polymers-Nucleic AcidsMonomers- Nucleotide5
6766171471Polymers-ProteinsMonomers-Amino Acids6
6766209507DehydrationA chemical reaction in which 2 molecules become covalently bonded to each other with the removal of a water molecule7
67661805511. Synthesisbuilding polymers -dehydration -covalent bonds between monomers -endergonic -enzyme catalyst8
6766230005Between MonomersCovalent bonds9
6766232574Endergonicrequires energy10
6766238202Enzyme Catalysta macromolecule serving as a catalyst, a chemical agent that speeds the rate of reaction without being consumed by the reaction -most are proteins11
6766270738B. Breakdown-hydrolysis -energy released ATP-ADP -digestion12
6766285001Hydrolysisa chemical reaction that breaks bonds between two molecules by the addition of water; functions in disassembly of polymers to monomers13
6766301532Digestionthe breaking down of food into molecules small enough for the body to absorb14
6766310220Macromoleculesproteins, nucleic acids, lipids, carbohydrates15
6766322167Carbohydratessugars and starches16
6766324805Functions of Carbsstructure, energy, storage17
6766353035Monosaccharideshave a molecular formula that are multiple of the unit CH2O -glucose is most common18
6766368202Glycosidic Linkagesjoins 2 monosaccarides making a disaccharide (sucrose most common-table sugar) -it is a covalent bond formed between 2 monosaccharides by a dehydration reaction19
6766384134In CarbsShape matters20
6776342605Sucrose- Carbsmade of glucose and fructose21
6776346000Carbs- Alpha glucoseused to form polymer starch22
6776347353Carbs- Beta glucoseused to form polymer cellulose23
6776351271Chemical equilibriumbetween linear and ring structures favors rings24
6776356309Polysaccharidesthe polymers of sugars, have storage and structural roles -their structure and function are determined25
6776361663DisaccharidesLactose Intolerance26
6776363997Lipidsare the one class of large macromolecules that does not include the polymers -they mix poorly if at all with water -are hydrophobic b/c they consist mostly of hydrocarbons27
6776375474Hydrocarbonsform covalent bonds28
6776378351Most important lipidsfats, phospholipids, and steroids29
6776387390Lipids-Usescell membranes, insulation (trap heat), cushioning organs, sufactants on lungs, hormones, energy storage: >2x carbs30
6776397808Fats and Oilsgylcerol + 3 fatty acids (ester linkage triacylglycerol) -nonpolar covalent bonds (c-h) -single or double31
6776408481Fatty acidsvary in length(number of carbons) and in the # and locations of double bonds32
6776415632Saturated Fatty Acidshave the maximum number of hydrogen atoms possible and no double bonds - in animals for insulation -ex. butter, lard33
6776421945Unsaturated Fatty Acidshave one or more double bonds ex. olive, fish, vegetable oil, plants and fish use it34
6776427710Monosaturated1 double bond35
6776429585Polysaturated>1 bond36
6776431392Trans Fatunsaturated w/ trans-isomer fatty acids -no bends -hard to bond with -hydrogenation (more saturated) ex. margarine37
6776444607Trans Fat Risk- Triglyceridestype of fat found in blood hardening of arteries38
6776449606Trans Fat Risk- Lp(a) liproteinLp(a) is a type of LDL cholesterol, causes more inflammation39
6776454788Phospholipidsglycerol + 2 fatty acids -3rd hydroxyl group -hydrophilic polar head -2 hydrophobic -bilayers -self assemble in presence of H2O40
6776464168Steroids4 fused C rings + functional groups ex. cholesterol (synthesized in liver), estradiol, testosterone, pheromones41
6776473843Proteins-polypeptides - a biologically functional molecule that consists of one or more polypeptides42
6776478915Protein Usesstructure, storage, movement, immunity, enzymes, critical in every biological process43
6776488343Enzymes-most proteins are - control metabolism in a cell selectively facilitating chemical reactions -selective acceleration of chemical reactions ex. digestion44
6776498993Proteins-Monomers- amino acids - same base -side chain ("r" group) varies - physical and chemical properties determine characteristics= role polypeptide45
6776517460Amino Acids-9 non-polar AAs -6 polar AAs (moderately hydrophilic side chains) -Charged AAs (every hydrophilic side chains)46
6776533055Protein Formation-peptide bonds - this is a dehydration reaction between amine and carboxyl - joined one at a time to form proteins, using covalent linkages called peptide bonds47
6776543613Protein Conformation (Structure)- 1-linear sequence of AAs -varies in: #, order, identity -b/c of chemistry of amino acid polymerization - always begin with amine and end with carboxyl -length, order, and identity of amino acid distinguishes 2 different proteins48
67765610452nd Structure-H bonding between peptide bonds -common shapes: alpha helixes, beta-pleated sheet -these structures arise b/c different peptide bonds can hydrogen bond to each other id oriented a certain way49
67765767033rd structure-3D structure determines protein function -interactions between R groups -controlled by 1st structure50
67765878274th Structure-only some proteins -2+polypeptides permanently bond together to form a functional unit51
6776599357Denaturationthe loss of protein's native structure - denatured protein is biologically inactive and uncoiled -does not disrupt primary structure' ex. egg=permanent ex. warmed milk- can be cooled=temporary52
6776607000Unraveling of Proteinscan be caused by pH, salt concentration, temp, or other environmental factors53
6776620743Nucleic acidsthe amino acid sequence of a polypeptide is programmed by a unit of inheritance called a gene (consist of DNA, a nucleic acid made of monomers called nucleotides)54
6776641101The Roles of Nucleic Acids-DNA provides directions for its own replication -DNA directs synthesis of messenger RNA (mRNA), controls protein synthesis -gene expression, important because the flow of genetic info can be summarized as DNA-RNA-Protein55
67766593332 Types of Nucleic AcidsDNA- deoxyribonucleic acid RNA- ribonucleic acid56
6776664936Nucleotides- N containing base -Phosphate - 5 Carb -nulceoside (nitrogenous base and sugars)57
6776672376BasesCytosine, thymine, uracil, adenine, guanine58
6776682815Pyrimidines-6 member ring -cytosine, thymine, uracil59
6776692897Purinesfused 5 and 6 member rings -adenine and guanine60
6776698982DNA/RNA Synthesisa DNA strand (or DNA molecule) is synthesized by bonding the phosphate of one nucleotide61
6776708281Bonding the phosphate of one nucleotide for DNA/RNA synthesisthis covalent bonding results in a phosphodiester linkage and creates a repeating backbone of sugar-phosphate units, with the bases extended sideways62
6776724468DNA strands held together by H bonds- 2 purines will not form a base-pair -2 pyrimidines will not form a base pair63
6776728769RNAbase-uracil sugar-ribose -single stranded -molecule usually shorter64
6776733860DNAbase-thymine sugar-deoxyribose double strands65

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