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Chapter 43 Immune System Flashcards

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606905328innate immunityImmunity that is present before exposure and effective from birth. Responds to a broad range of pathogens.0
606905329acquired immunityImmunity that is present only after exposure and is highly specific.1
606905330lymphocytesWhite blood cells.2
606905331antibodiesProtein that is produced by lymphocytes and that attaches to a specific antigen.3
606905334neutrophilsMost abundant white blood cell., The most abundant type of white blood cell. Phagocytic and tend to self-destruct as they destroy foreign invaders, limiting their life span to a few days.4
606905336complement systemA group of about 30 blood proteins that may amplify the inflammatory response, enhance phagocytosis, or directly lyse extracellular pathogens.5
606905337interferonProtein produced by cells in response to being infected by a virus; helps other cells resist the virus.6
606905338inflammtory responseInnate response with the purpose of containing a site of damage, localizing the response, eliminating the invader and restore tissue function.7
606905339histamineChemical stored in mast cells that triggers dilation and increased permeability of capillaries.8
606905340natural killer (NK) cellsThese cells kill cancer cells and cells infected with viruses. They bind to their targets and deliver a lethal burst of chemicals to produce holes in the target cell's membrane leading to its destruction.9
606905341antigenAny foreign molecule that is specifically recognized by lymphocytes and elicits an immune response.10
606905342epitopeSmall, accessible portion of an antigen that can be recognized.11
606905343B lymphocytes (B cells)Lymphocyte that matures in the bone marrow and secretes antibodies.12
606905344T lymphocytes (T cells)Lymphocyte that matures in the thymus and acts directly against antigens in cell-mediated immune responses.13
606905345immunoglobulinsSecreted antibodies.14
606905346antigen presentationThe process by which an MHC molecule binds to a fragment of an intracellular protein antigen and carries it to the cell surface, where it is displayed and can be recognized by a T cell.15
606905347thymusGland in the thoracic cavity above the heart where T lymphocytes mature.16
606905348memory cellsGeneral term for lymphocytes that are responsible for immunological memory and protective immunity.17
606905349primary immune responseImmune response the first time the body is exposed to a particular antigen. Does not peak until 10-17 days after exposure.18
606905350secondary immune responseImmune response after the body has already been exposed to a specific antigen. Response is faster, of greater magnitude, and more prolonged.19
606905351humoral immune responseThe branch of acquired immunity that involves the activation of B cells and that leads to the production of antibodies, which defend against bacteria and viruses in body fluids.20
606905352cell-mediated immune responseThe branch of acquired immunity that involves the activation of cytotoxic T cells, which defend against infected cells.21
606905353helper T cellsActivate macrophages, B cells and T cells.22
606905354active immunityA form of acquired immunity in which the body produces its own antibodies against disease-causing antigens.23
606905355passive immuniteImmunity conferred by transferring antibodies from an individual who is immune to a pathogen to another individual.24
606905356immunizationThe deliberate exposure of a pathogen to produce memory cells.25
606905358Rh factorRefers to the presence or absence of the Rh antigen on red blood cells.26
606905359graft versus host reactionWhen lymphocytes in donated bone marrow react against the recipient.27
606905360anaphylactic shockA severe reaction that occurs when an allergen is introduced to the bloodstream of an allergic individual. Characterized by bronchoconstriction, labored breathing, widespread vasodilation, circulatory shock, and sometimes sudden death.28
606905362autoimmune diseasesDiseases caused when the immune system loses tolerance for self and turns against certain molecules in the body.29
606905364Acquired Immunodeficiency Syndrome (AIDS)The most advanced, and fatal, stage of an HIV infection.30
606905370B cell receptorThe antigen receptor on B cells: a Y-Shaped, membrane-bound molecule consisting of two identical heavy chains and two identical light chains linked by disulfide bridges and containing two antigen-binding sites.31
606905372T cell receptorAntigen receptors on a T cell. Unlike antibodies, T cell receptors are never produced in a secreted form.32
608378050Major histocompatibility compex (MHC)Binds to a fragment of an antigen within a cell and presents it on the surface of the membrane.33
608378051cytotoxic T cells or "killer T cells"T cells that directly attack infecting organisms; these cells attack antigen labeled foreign or host tissue.34

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