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CHAPTER 5: Histology Flashcards

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6194538334Histology or Microscopic Anatomy-the study of tissues and how they are arranged into organs0
6194538335Tissue-similar cells and cell products (matrix)1
6194538336Matrix-ground substance and fibers2
6194538337Primary germ layers-the three layers (ectoderm, mesoderm, endoderm) of the late gastrulation, which develop into all parts of an animal.3
6194538338Ectoderm-outermost germ layer -the germ layer that gives rise to the skin and nervous system4
6194538339Endoderm-innermost germ layer -develops into the linings (mucous membrane) of the digestive tract and much of the respiratory system5
6194538340Mesoderm-middle germ layer -the germ layer that gives rise to the blood, bones and muscles6
6194538341Mesenchyme-embryonic connective tissue that arises from mesoderm and produces all types of connective tissues7
6194538342Histological sections-tissue preparations mounted on microscope slides. -artificially colored to bring out detail8
6194538343Fixative-preservative for cells9
6194538344Stains-artificial color that enhances details10
6194538345Longitudinal Section|11
6194538346Cross Section_12
6194538347Transverse Section_13
6194538348Oblique Section/14
6194538349Smears-tissue is rubbed or spread across the slide rather than sliced15
6194538350Spreads-tissue is laid out on the slide16
6194538351Sections-tissue is sliced17
6194538352Epithelial Tissue-a body tissue that covers the interior and exterior surfaces of the body18
61945383536 Functions of Epithelial TissueFunctions: Protection, Secretion, Excretion, Absorption, Filtration, Sensation19
6194538354Basement Membrane-cells at the base (basal cells) of an epithelial layer are attached to this -regulates the exchange of materials between the epithelium and the underlying tissues20
6194538355Simple Epithelium-has only one layer of cells21
6194538356Simple Squamous-has only one layer of cells, with a scale like shape22
6194538357Simple Cuboidal-has only one layer of cells, with a cube like shape23
6194538358Simple Columnar-has only one layer of cells, with a colum like shape24
6194538359Pseudostratified Columnar-has only one layer of cells, but appears to be stratified columnar25
6194538360Goblet Cells-secrete a glycoprotein called mucin26
6194538361Stratified Epithelia-has more than one layer of cells27
6194538362Stratified Squamous-has more than one layer of cells, with a scale like shape28
6194538363Stratified Cuboidal-has more than one layer of cells, with a cube like shape29
6194538364Stratified Columnar-has more than one layer of cells, with a colum like shape30
6194538365Transitional Epithelium-somewhat resembles stratified squamous epithelium, but surface cells are rounded, not flattened, and often bulge at surface31
6194538366Exfoliation or Desquamation-epithelium dies and flakes off of the surface32
6194538367Nonkeratinized-lacks the surface layer of dead cells -moist and slippery33
6194538368Keratinized-epithelium, found in the epidermis, is covered with a layer of compact, dead squamous cells -packed with the durable protein keratin -dry and water resistant34
6194538369Connective Tissues-cells that occupy less space than the extracellular matrix35
61945383708 Functions of Connective TissueFunctions: Binding of organs, Support, Physical protection, Immune protection, Movement, Storage, Heat production, Transport36
6194538371The cells of fibrous connective tissueCommon Cells: Fibroblasts, Macrophages, Leukocytes, Plasma cells, Mast cells, Adipocytes37
6194538372Fibroblasts-produce fibers and ground substance38
6194538373Macrophages-cells that wander through the connective tissues, where they engulf and destroy bacteria, other foreign particles, and dead or dying cells of our own body.39
6194538374Leukocytes-react against bacteria, toxins and other foreign substances40
6194538375Plasma cells-synthesize disease-fighting proteins called antibodies41
6194538376Mast cells-secrete heparin (inhibits blood clotting) and histamine (dilates blood vessels)42
6194538377Adipocytes-specialized fat cells whose cytoplasm contains nothing but triglycerides43
61945383783 types of fibers-Collagenous Fibers, Reticular fibers, Elastic fibers44
6194538379Collagenous Fibers-fibers made of collagen, that are tough, flexible and resist stretching45
6194538380Reticular fibers-thin collagen fibers coated with glycoprotein that form a spongelike framework46
6194538381Elastic fibers-fibers made of a protein called elastin47
6194538382Elastin-a protein whose coiled structure allows it to stretch and recoil like a rubber band.48
6194538383Ground Substance-a gelatinous substance that is made of 3 large molecules glycosaminoglycans, proteoglycans, and adhesive glycoproteins49
6194538384Glycosaminoglycan-long polysaccharide composed of unusual disaccharides called amino sugars -it includes chondroitin sulfate, heparin (an anticoagulant) and hyaluronic (lubricant in the joints) -good at attracting and holding water.50
6194538385Chondroitin Sulfate-the most abundant type of glycosaminoglycan that makes cartilage stiff51
6194538386Proteoglycan-gigantic molecule that forms thick colloids which slows the spread of pathogenic organisms through the tissues -also bind the cell to the matrix52
6194538387Adhesive Glycoproteins-bind plasma membrane proteins to collagen and proteoglycans outside the cell53
6194538388Loose Connective Tissue-ground substane occupies more space than the cells and fibers54
6194538389Dense Connective Tissue-fiber occupies more space than the cells and ground substance55
6194538390Areolar Tissue-Fibers: mostly collagenous fibers -Cells: all of the 6 cells found in connective tissues -found in almost every part of the body -has an abundance of blood vessels56
6194538391Reticular Tissue-Fibers: reticular fibers -Cells: fibroblasts -forms the structural framework (spongy) for some viscera57
6194538392Dense Regular Connective Tissue-very little space between parallel collagen fibers58
6194538393Elastic Tissue-a type of dense regular tissue with added elastic fibers -has more fibroblasts (larger nuclei) than normal dense regular tissue59
6194538394Dense Irregular Connective Tissue-very little space between collagen fibers that run in random directions60
6194538395Adipose tissue-Fibers: areolar tissue and reticular tissue -Cells: adipocytes61
6194538396White Fat-is the only significant adipose tissue of the adult body62
6194538397Brown fat-abundance of blood vessels and mitochondria -mitochondria don't produce ATP only energy as heat only in children and under.63
6194538398Cartilage-a strong connective tissue that is more flexible than bone64
6194538399Chondroblasts-cartilage producing cell that secrete matrix until surrounded65
6194538400Chondrocytes-cartilage producing cell enclosed in a lacunae66
6194538401Lacunae-a little cavity that a cell becomes enclosed in67
6194538402Hyaline Cartilage-fine collagen fibers that appear glassy68
6194538403Elastic Cartilage-cartilage with abundant elastic fibers; more flexible than hyaline cartilage.69
6194538404Fibrocartilage-tough form of cartilage, made of thick bundles of collagen fibers embedded in chondroitin sulfate ground substance70
6194538405Perichondrium-a sheath of dense irregular connective tissue surrounding most hyaline and elastic cartilage71
6194538406Osseous Tissue-is a hard, calcified connective tissue that composes the skeleton72
6194538407Spongy Bone-fills the heads of the long bones and forms the middle layer of flat bones -always covered by a shell of compact bone73
6194538408Compact Bone-is a denser calcified tissue with no spaces visible to the naked eye74
6194538409Central Canals175
6194538410Concentric Lamellae376
6194538411Osteon77
6194538412Lacunae of Osseous Tissue478
6194538413Canaliculi279
6194538414Periosteum-a sheath of dense irregular connective tissue covering the bone80
6194538415Blood-Fibers: none -Cells: erythrocytes, leukocytes and platelets -GS: blood plasma (more abundant in GS than anything)81
6194538416Blood Plasma-the ground substance in blood82
6194538417Formed Elements-collective of cells inside blood (erythrocytes, leukocytes, and platelets)83
6194538418Erythrocytes-transport O2 and CO284
6194538419Platelets-small cell fragments that are involved in clotting and secreting growth factors that promote blood vessel growth and maintenance85
6194538420Excitable Tissues-tissues such as neurons or muscles that are capable of producing membrane potential86
6194538421Membrane Potential-the voltage across a cell's plasma membrane.87
6194538422Nervous tissue-is specialized for communication by means of electrical and chemical signals -Cells: neurons and glial cells (which are more abundant)88
6194538423Neurons-detect stimuli, respond quickly, and transmit coded information rapidly to other cells89
6194538424Glial Cell-protect and assist the neurons90
6194538425Neurosoma-cell body of a neuron that houses the nucleus and most other organelles91
6194538426Dendrites-branch out of the neurosoma -receive signals from other cells and conduct messages to the neurosoma92
6194538427Axon (Nerve Fiber)-sends outgoing signals to other cells93
6194538428Muscular Tissue-contract moving various parts of the body when stimulated94
6194538429Skeletal Muscle-striated and voluntary95
6194538430Muscle Fibers-long, slender cells that make up (skeletal) muscles96
6194538431Sphincter-muscular rings or cuffs that open and close body passages97
6194538432Striations-alternating vertical light and dark bands98
6194538433Cardiac Muscle-striated and involuntary -only located on the heart99
6194538434Cardiocytes-short muscle cells of the heart100
6194538435Myocytes-short muscle cells (smooth or cardiac muscle)101
6194538436Intercalated Discs-junctions that join cardiocytes together end to end102
6194538437Smooth Muscle-fusiform and involuntary103
6194538438Visceral Muscle-muscles of the viscera (internal organs) -usually smooth muscle104
6194538439Cell Junctions-The connections between one cell and another105
6194538440Tight Junction-completely encircles an epithelial cell near its apical surface creating a seal -linked by transmembrane cell-adhesion proteins106
6194538441Desmosome-doesn't completely encircles an epithelial cell -enables a tissue to resist mechanical stress107
6194538442Hemidesmosomes-half desmosomes that attach the basal cells to the basement membrane108
6194538443Gap Junction-a channel that connects cells together -allows ions, glucose, amino acids, and other small solutes to pass directly from one cell to it's neighbor109
6194538444Gland-a cell or organ that secretes substances for use elsewhere in the body or for elimination as waste110
6194538445Secretion-a product useful to the body that is released111
6194538446Excretion-a waste product that is released112
6194538447Exocrine Glands-secrete chemical substances into ducts that lead either to other organs or out of the body113
6194538448Duct-an epithelial tube that moves secretion to the surface114
6194538449Endocrine Glands-lost contact with the surface and have no ducts -secrete their products directly into the blood115
6194538450Unicellular glands-secretory cells found in an epithelium that is predominantly nonsecretory -ex: goblet cells116
6194538451Capsule-encloses gland117
6194538452Septa or Trabeculae-extensions of the capsule that divide the interior of glands118
6194538453Lobes-the compartments made by septa119
6194538454Lobules-created by fine septa further dividing lobes120
6194538455Stroma-connective tissue framework of the gland i.e. capsule and septa121
6194538456Parenchyma-cells that perform the tasks of synthesis and secretion122
6194538457Simple-a single unbranched duct123
6194538458Compound-branched ducts124
6194538459Tubular-duct and secretory portion are of uniform diameter125
6194538460Acinar-secretory gland form a dilated sac126
6194538461Acinus or Alveolus-secretory cells form a dilated sac127
6194538462Tubuloacinar Gland-secretory cells in both the tubular and acinar portions128
6194538463Serous Glands-produce relatively thin, watery fluids129
6194538464Mucous Glands-has cells that secrete a glycoprotein called mucin (mucin absorbs water and forms the sticky product mucus)130
6194538465Mixed Glands-contain both serous and mucous cells131
6194538466Cytogenic Glands-release whole cells (testes and ovaries)132
6194538467Eccrine Glands or Merocrine Glands-have vesicles that release their secretion by exocytosis133
6194538468Holocrine Glands-cells accumulate a product and then the entire cell disintegrates134
6194538469Apocrine Glands-same as merocrine with the exception of larger lumen135
6194538470Cutaneous Membrane-the skin -dry136
6194538471muscularis mucosae-a layer of smooth muscle in mucous membrane137
6194538472lamina propria-an areolar connective tissue layer of mucous membrane138
6194538473Mucous Membrane-lines passages that open to the exterior environment -layers; (1) an epithelium (2) lamina propria (3) muscularis mucosae139
6194538474Serous Membrane-a simple squamous epithelium resting on a thin layer of areolar connective tissue -produces watery fluid140
6194538475Serous Fluid-watery product of serous membrane141
6194538476Mesothelium-the epithelium found in serous membranes lining the ventral body cavity and covering its organs142
6194538477Endothelium-layer of simple squamous epithelium lining cavities of heart, blood & lymphatic vessels143
6194538478Synovial Membranes-lines some joints -made only of connective tissue144
6194538479Hyperplasia-tissue growth through cell multiplication145
6194538480Hypertrophy-the enlargement of preexisting cells146
6194538481Neoplasia-the development of a tumor147
6194538482Differentiation-process in which cells become specialized in structure and function148
6194538483Metaplasia-a change from one type of mature tissue to another149
6194538484Stem Cells-undifferentiated cells that are not yet performing any specialized function150
6194538485Developmental Plasticity-range of mature cell types that a stem cell can become151
6194538486Embryonic Stem Cells-compose the early human embryo152
6194538487Totipotent-have the potential to develop into any type of fully differentiated human cell153
6194538488Pluripotent-cells of the inner cell mass -can still develop into any cell type of the embryo, but not into the accessory organs of pregnancy154
6194538489Adult Stem Cells-undifferentiated cells found among differentiated cells in a tissue or organ155
6194538490Multipotent-able to develop into two or more different cell lines, but not just any type of body cell.156
6194538491Unipotent-able to develop into only one cell type157
6194538492Regeneration-replacement of dead or damaged cells by the same type of cells as before158
6194538493Fibrosis-replacement of damaged tissue with scar tissue, composed mainly of collagen produced by fibroblasts159
6194538494Granulation Tissue-deeper portions of the clot become infiltrated by capillaries and fibroblasts and transform into a soft mass160
6194538495Atrophy-the shrinkage of a tissue through a loss in cell size or number161
6194538496Necrosis-premature tissue death162
6194538497Infarction-the sudden death of tissue, such as cardiac muscle or brain tissue -occurs when its blood supply is cut off163
6194538498Gangrene-any tissue necrosis resulting from an insufficient blood supply, usually involving infection164
6194538499Decubitus Ulcer-a form of dry gangrene that occurs when an immobilized person, have continual pressure on the skin cutting off blood flow to the area165
6194538500Apoptosis-is the normal death of cells that have completed their function and best serve the body by dying166

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