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Chapter 8: Metabolism (AP Biology) Flashcards

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6212478814metabolismsum total of an organism's chemical reactions0
6212478815chemistry of life (is...)is organized into metabolic pathways1
6212478816metabolic pathway (begins...)begins with a specific molecule, which is then altered in a series of defined steps to form a specific product2
6212478817enzymeA specific ____________ catalyzes each step of the pathway3
6212478818anabolic pathways (functions)building up molecules; stores energy (in bonds); utilizes condensation or dehydration synthesis4
6212478819catabolic pathways (functions)breaking down molecules; releases energy; utilizes hydrolysis5
6212478820bioenergeticsthe study of how energy flows through living organisms6
6212478821energythe capacity to cause change7
6212478822kinetic energythe energy associated with the relative motion of objects8
6212478823thermal energykinetic energy associated with the random movement of atoms or molecules9
6212478824potential energythe energy that matter possesses because of its location or structure10
6212478825chemical energyused to refer to the potential energy available for release in a chemical reaction (stored in bonds)11
6212478826on a diving platformDoes a diver have more potential energy on a diving platform or in the water? (INSERT: on a diving platform/in the water)12
6212478827potential, kineticDiving (or another other drop) converts _______________ energy to ______________ energy (INSERT: ____________, ____________)13
6212478828thermodynamicsthe study of energy transformations that occur in a collection of matter14
6212478829isolated system (or closed system; is...)is unable to exchange either energy or matter with its surroundings15
6212478830(in) open systemsenergy and matter can be transferred between the system and its surroundings (organisms are _______ _______________)16
6212478831closed, equilibriumA ___________ system, eventually it reaches ______________ and no more work can be done. (INSERT: ____________, _____________)17
6212478832First Law of Thermodynamics (states...)states that energy can be transferred and transformed, but cannot be created or destroyed ("conservation of energy")18
6212478833Second Law of Thermodynamics (states...)states that every energy transfer or transformation increases the entropy of the universe19
6212478834Entropy (∆S)a measure of disorder or randomness; the more random a collection of matter, the greater its ___________20
6212478835Heatthe energy of random molecular motion21
6212478836Spontaneous (reaction)always going to a more stable position (increasing entropy); decreasing Free Energy (∆G); can occur WITHOUT the input of energy22
6212478837Non-spontaneous (reaction)going to a less stable position (decreasing entropy); increasing Free Energy (∆G ); needs energy input to occur23
6212478838EntropyFor a process to occur without energy input, it must increase the ___________ of the universe24
6212478839ordered, lessCells create _____________ structures from ___________ ordered materials (INSERT: ___________, __________)25
6212478840negativeOnly processes with a ____________ ∆G are spontaneous26
6212478841Hchange in enthalpy or total energy (∆__)27
6212478842Schange in entropy (∆__)28
6212478843Ttemperature in Kelvin29
6212478844Equilibriumstate of maximum stability30
6212478845Free energy (is...)is a measure of a system's instability, its tendency to change to a more stable state31
6212478846SpontaneousDuring a ____________________ change, free energy decreases and the stability of a system increases32
6212478847∆G = ∆H - T∆SThe change in free energy, ∆G, can be calculated for any specific chemical reaction by applying the following equation (∆G = ∆H - T∆S or ∆G = ∆Gfinal state − ∆Gstarting state; copy and paste on of the equations)33
6212478848Free energy (is...)is the portion of a system's energy that can perform work when temperature and pressure are uniform throughout the system, as in a living cell34
6212478849Exergonicreleasing energy; reactants have MORE energy than products; ∆G = negative; spontaneous35
6212478850Endergonicabsorbing energy from environment; reactants have LESS energy than products; ∆G = positive; nonspontaneous36
6212478851SS or NS?: Catabolic (breaking down)37
6212478852SS or NS?: Exergonic (giving off E)38
6212478853SS or NS?: Breaking down39
6212478854SS or NS?: breaking bonds (hydrolysis)40
6212478855SS or NS?: release free energy41
6212478856SS or NS?: ∆G = Negative (Free energy decreases)42
6212478857SS or NS?: ∆S = Positive (entropy increases)43
6212478858SS or NS?: stability increases44
6212478859NSS or NS?: anabolic (building up)45
6212478860NSS or NS?: endergonic (absorbing E)46
6212478861NSS or NS?: building up47
6212478862NSS or NS?: making bonds (dehydration synthesis)48
6212478863NSS or NS?: storing free energy49
6212478864NSS or NS?: ∆G= Positive (free energy increases)50
6212478865NSS or NS?: ∆S = Negative (disorder (entropy) decreases)51
6212478866NSS or NS?: stability decreases52
6212478867Chemical workAn example of it is the synthesis of polymers from monomers (one of the three main kinds of work that a cell does)53
6212478868Transport workPumping substances across membranes (one of the three main kinds of work that a cell does)54
6212478869Mechanical workExamples are the beating of cilia, contraction of muscle cells, and movement of chromosomes during cellular respiration (one of the three main kinds of work that a cell does)55
6212478870energy couplingCells manage their energy resources to do this work by _________ _____________, using an exergonic process to drive an endergonic one (ANSWER IS TWO WORDS)56
6212478871endergonic, phosphateIn the cell, the energy from the hydrolysis of ATP (exergonic) is directly coupled to ______________ processes by the transfer of the ______________ group to another molecule (INSERT: ______________, ______________)57
6212478872ATPadenosine triphosphate; the energy molecules for cells58
6212478873ATPcomposed of the sugar ribose, the nitrogen base adenine, and three phosphate groups59
6212478874Phosphorylationtransferring a phosphate group to some other molecule, such as a reactant60
6212478875phosphorylated intermediaterecipient molecule of phosphorylation61
6212478876ATP cycletransferring of a phosphate can transfer energy from one molecule to another62
6212478877Enzymea protein that acts as a catalyst63
6212478878Catalysta molecule that speeds up a chemical reaction WITHOUT being changed or consumed during the reaction64
6212478879Activation Energythe energy needed for a reaction to occur65
6212478880lowering, reactionEnzymes work by ______________ the amount of activation energy required for a ______________ to occur (INSERT: _______________, _______________)66
6212478881Heat (speeds...)speeds up all reactions, not just those that are needed; also denatures proteins and kills cells67
6212478882Substratethe reactant that an enzyme acts on68
6212478883Enzyme-substrate complexThe enzyme binds to a substrate, or substrates, forming an...69
6212478884Induced Fit Theory (says...)says that when the substrate binds with the enzyme at the active site, the enzyme may change shape slightly to have more of a "snug" fit70
6212478885R groups, catalyzeThe ______________ of a few amino acids on the active site _______________ the conversion of substrate to product (INSERT: ______________, ________________)71
6212478886unaffected, reuseableEnzymes are ________________ by the reaction and are ________ (INSERT: ______________, _______________)72
6212478887metabolic, reverse, equilibriumMost __________________ enzymes can catalyze a reaction in both the forward and _____________ directions; in the direction of __________________ (INSERT: ______________, _______________, _______________)73
6212478888high, engagedAt ____________ substrate concentrations, the active sites on all enzymes are ______________ (INSERT: ____________, ________________)74
6212478889optimal conditionseach enzyme works best at certain ______________ ________________75
62124788906-8, 2, 8This optimal pH falls between ______ for most enzymes. However, digestive enzymes in the stomach are designed to work best at pH __, whereas those in the intestine have an optimal pH of __. (INSERT: ________, _____, ____)76
6212478891cofactorsnon-protein helpers (usually minerals)77
6212478892coenzymesorganic cofactors (usually vitamins)78
6212478893activatesCofactor binding ____________ the protein (a verb)79
6212478894Competitive Inhibitionwhere an inhibitor mimics the shape of the substrate and gets in the way of the active site of the enzyme; so it is competing for the active site80
6212478895Non-competitive Inhibitionan inhibitor binds to an allosteric site (a site on the enzyme that is NOT the active site) and therefore changes the shape of the active site on the enzyme81
6212478896Allosteric sitea spot on an enzyme away from the active site where an inhibitor OR activator can bind and affect the function of that enzyme82
6212478897binding, functionalThe ____________ of an activator stabilizes the conformation that has __________________ active sites (INSERT: _________________, __________________)83
6212478898inhibitor, inactiveThe binding of a(n) _______________ stabilizes the _______________ form of the enzyme (INSERT: _________________, __________________)84
6212478899Cooperativitythe binding of a substrate in the active site of ONE of the subunits can force the other subunits to stay in the active conformation85
6212478900Feedback Inhibitionthe switching OFF of a metabolic pathway by one of its end products, the end product acts as an inhibitor of one of the enzymes in the pathway86
6212478901Feedback Inhibition (helps...)helps cells regulate and not waste any resources by making TOO MUCH of a certain product87
6212478902Cooperativity (amplifies...)amplifies the response of enzymes to substrates, priming the enzyme to accept additional substrates88
621247890335 to 40 degreesMost human enzymes have optimal temperatures of about ____ to _____ degrees Celsius (INSERT: ____ to _____ degrees)89
6212478904carbohydrates, fatsWhat are two examples of chemical energy? (INSERT: _______________________, _____________________)90
6212478905ATPWhat is the body's energy currency?91
6212478906carbon dioxide, waterWhat are two examples of chemical waste? (INSERT: _______________________, _____________________)92
6212478907convertedenergy can be ________________ from one form to another93
6212478908transformOrganisms _______________ energy94
6212478909Allosteric activatormodifies the active site of the enzyme so that the substrate can bind to the active site95
6212478910Allosteric inhibitora regulatory molecule that binds to an enzyme in a spot different from the active site for another molecule, causing a conformational change in the active site for the second molecule, preventing binding96
6212478911HeatMuch of the increased entropy of the universe takes the form of increasing ________97

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