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DNA Structure and Function (Chps. 12 and 13) Flashcards

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2115783244transformationmodification of a cell or bacterium by the uptake and incorporation of genetic material (DNA). Can change harmless bacteria into disease - causing form.0
2115816316bacteriophageA virus that infects bacteria1
2116043467Deoxyribonucleic acidDNA. A double-stranded, helical nucleic acid molecule capable of replicating and determining the inherited structure of a cell's proteins.2
2115820257base pairingPrinciple that bonds in DNA can form only between adenine and thymine and between guanine and cytosine.3
2115828743nucleotideThe building blocks of DNA and RNA, consisting of a five-carbon sugar covalently bonded to a nitrogenous base and a phosphate group.4
2115831225DeoxyriboseA five-carbon sugar found in DNA.5
2115834511phosphate groupA functional group consisting of a phosphorus atom covalently bonded to four oxygen atoms. major component of nucleotides.6
2115837269nitrogen baseThe chemicals that make up the rungs of the DNA ladder and store genetic information.7
2115838218Charghaff's ruleThe rule that Adenine bonds to Thymine and Cytosine bonds to Guanine in DNA8
2115871548hydrogen bondsVery weak bond created by the attraction of a slightly positive hydrogen atom to a slightly negative portion of another molecule. Hold the 2 strands of9
2115884552Double HelixA shape like a coiled spring, used to describe the structue of DNA molecules.10
2115890179antiparallelThe opposite arrangement of the sugar-phosphate backbones in a DNA double helix.11
2115971621complimentary (DNA)The concept that the 2 strands of a DNA molecule are opposite in terms of Base pairing A-T and C-G.12
2115996840ReplicationCopying process by which a cell duplicates its DNA13
2115998832HelicaseAn enzyme that untwists the double helix of DNA at the replication forks.14
2116001252DNA polymeraseAn enzyme that catalyzes the elongation of new DNA at a replication fork by the addition of free nucleotides to the existing chain.15
2116017536Replication ForkA Y-shaped region on a replicating DNA molecule where new strands are growing.16
21160050945' to 3'The Direction that DNA or RNA always forms new polymers17
2116033227leading strandStrand of a DNA molecule during DNA replication; replication is continuous without Okazaki fragments.18
2116034829Lagging StrandA discontinuously synthesized DNA strand that elongates in a direction away from the replication fork. produces Okazaki fragments19
2116039270Okazaki fragmentsShort fragments of DNA that are a result of the synthesis of the lagging strand during DNA replication.20
2116023137telomeresDNA at the tips of chromosomes. particularly difficult to replicate.21
2116026569TelomeraseAn enzyme that catalyzes the lengthening of telomeres in eukaryotic reproductive cells. this enzyme is turned off in adult cells.22
2116043468Ribonucleic Acid(RNA) single-stranded nucleic acid that contains the sugar ribose. There are 3 main types.23
2116202551RiboseA five-carbon sugar present in RNA.24
2116203455UracilA nitrogen base found only in RNA. Takes the place of Thymine (T) and Bonds to Adenine (A).25
2116057030Messenger RNA (mRNA)A single-stranded RNA molecule that carries the instructions from a gene to make a protein (translation).26
2116060433Ribosomal RNA (rRNA)important component of ribosomes. involved in the process of translation.27
2116067517transfer RNA (tRNA)form of RNA that brings amino acids to ribosomes during protein synthesis.28
2116068993transcriptionThe process whereby the DNA sequence in a gene is copied into mRNA29
2116073186RNA polymeraseAn enzyme that links together the growing chain of RNA nucleotides during transcription, using a DNA strand as a template.30
2116086474promoterDNA sequence where RNA polymerase attaches and initiates transcription.31
2116087529intronsA noncoding, intervening sequence within a eukaryotic gene.32
2116088427exonsA coding region of a eukaryotic gene. Exons, which are expressed, are separated from each other by introns.33
2116091761genetic codeSet of rules that determine how a nucleotide sequence is converted into the amino acid sequence of a protein.34
2116094276codonA three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid; the basic unit of the genetic code.35
2116110700Start codonAUG; the codon that begins all RNA molecules. Codes for Methionine.36
2116115259stop codonCodon that signals to ribosomes to stop translation37
2116117654translationThe process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm.38
2116104289polypeptidechain of many amino acids linked together. Helps form proteins.39
2116103195amino acidBuilding blocks of protein40
2116122329anticodongroup of three bases on a tRNA molecule that are complementary to an mRNA codon.41
2116126954central dogmaDNA -> RNA -> Protein.42
2116133028gene expressionThe process by which a gene produces its product and the product carries out its function. Genes are transcribed into mRNA which are translated into proteins, and those proteins carry out a function with in the cell43
2116144148mutationheritable changes in genetic information (DNA).44
2116152579gene mutationA change in the sequence of the bases in a gene, which changes the structure of the polypeptide that the gene codes for.45
2116154866Chromosomal mutationA change in the chromosome structure, resulting in new gene combinations.46
2116159407point mutationA change in a gene at a single nucleotide pair.47
2116160507deletionChange to a gene or chromosome in which a fragment is removed.48
2116164132duplicationWhen a portion of a gene or chromosome is repeated.49
2116168618inversionA kind of mutation in which the order of the genes in a section of a chromosome is reversed.50
2116173065polyploidyCondition in which an organism has extra sets of chromosomes51

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