3940549763 | innate immunity | is always active against infection but cant target specific pathogens, is nonspecific near entry part of the body macrophage, monocytes, dentric cell, neutrophil release cytokins that trigger an immune response | 0 | |
3940555316 | adaptive immunity | targets a specific pathogen is slower to act but can maintain memory of pathogen B cells that when activated secrete antibodies that bind to invaders antigen T cells also recognize antigens both have memory divided into humoral (B cells and antibodies) and cell mediated (t cells) | 1 | |
3940594890 | organs of immnune system | bone marrow: makes WBC spleen: stores blood and activates B cells that turn into plasma cells that turn into antibodies thyums: T cells mature here lymph nodes: where immunue cells are stored and response can be mounted GALT: immune tissue near digestive system tonisils, adenoids, peyers patches in the sm intestine appendix | 2 | |
3940629212 | lymphatic system | ![]() | 3 | |
3940633522 | leukocytes | granolcytes and agranulocytes, both come from hematopoetic stem cells granules are toxic enzymes | 4 | |
3940645969 | WBC | ![]() | 5 | |
3940651819 | hematopoiesis | ![]() | 6 | |
3940716817 | non specific cellular defense | skin w/defensins ( enzymes) lysozyme in tears and saliva muscus membranes in resp system GI: gut bacteria and stomach acid complement system : blood proteins interferons: proteins that prevent viral replication and dispersion | 7 | |
3940763932 | cells of the innate immnune system, Macrophages | macrophages: a granulocyte, dervived from moncytes, phagocytes invader, engulfs it and presents little pieces of it to other cells using MHC which carries an antigen, also release cytokins that stimulate additional immune reponse | 8 | |
3940785392 | MCH class 1 | Major Histocompatibilty complex that carries antigen on a cell surface Class 1: endogeneous pathway of nucleated cells that binds antigens from inside the cell and presents them | 9 | |
3940816939 | MCH class 2 | displayed by professional antigen presenting cells like macrophages, dentritic cells, B cells exergenous pathway, antigens are from the environment | 10 | |
3940841537 | PRR pattern recognition receptors | macrophages and dentric cells special receptors to recruit the right type of immune cells | 11 | |
3940858433 | NK cells, innate immune system | non specific lymphocyte that produces apotocisis in virally infected cells , recognizes invaders since do not have MCH1 | 12 | |
3940880919 | granulocytes | neutophilis: most abundant, phagoctyes, can detected bacterica using chemotaxis, are what pus is made of eosinophil: allergic reaction release histamine and cause inflammation basophil: also involved in allergic response mast call: related to basophil | 13 | |
3940940133 | humoral immunity | involves the production of antibodies produced by B cells | ![]() | 14 |
3940965182 | antibodies or Ig | ![]() | 15 | |
3941004427 | cytotoxic immunity postive and negative selection | cell mediated response; T cells postive selection: for T cells that can respond to the specific antigen negative selection: killing cells that self react | 16 | |
3941025378 | 3 types of T cells | helper T cells; CD4 coordinate immune response , these are lost in HIV cytotoxix CD8: directly kill infected cells by injecting them with chemicals that promote aposostis , use MCH1 regulatory or suppressorc CD4:tone down immune response once infection has been fought , prevent autoimmune , MCH2 memory T cells | 17 | |
3941078258 | self antigen | so self cells are not attacked problem if autoimmune negative selection; thru T cells to kill of these autoimmume cells | 18 | |
3941098608 | active immunity | immune system stimulated to produce antibodies by exposure ie vaccine | 19 | |
3941105299 | passive immunity | the transfer of antibodies , ie to fetus | 20 | |
3941302056 | clonal selection | when only a certain cell with that specifc antibody for the specifc antigen is activated | 21 |
Immune System Flashcards
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