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Introduction to natural immunity ( Immunology Flashcards

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4442152189AntigenAn ______ is a foreign substance that causes an immune response in host.0
4442152190Cross ImmunityEdward Jenner's work with smallpox and cowpox is an example of ______ ______1
4442152191Rabies, Vaccination, and AttenuationLouis Pasteur's worked with _______, _____, and ________.2
4442152192Macrophages__________ are a cellular component of innate immunity.3
4442152193Acquired immunity_______ _______ is characterized by specificity for each individual pathogen, or microbial agent, and the ability to remember a prior exposure and results in an increased immune response.4
4442152194External system_______ ______: Attempts to prevent entry of pathogens.5
4442152195Internal system_______ _______: Deals with pathogens that gain entry.6
4442152196Unbroken, Lactic Acid, mucous and cilia, urine, stomach, Lysozyme, Normal FloraExternal Defenses include: ________ skin, _______ ______ in sweat, Respiratory tract's _________ secretions and _______, Flushing action of _______, plus it is slightly acidic, Acidity of the ________, ______ found in many secretions such as tears and saliva and is directly in oxidative killing of target cells, and _____ _____.7
4442152197Shorter lag phaseGive an example of secondary response.8
4442152198Natural Immunity_______ _____ depends on normally present body functions.9
4442152199Active_______ means the body forms antibodies10
4442152200Passive______ means antibody is formed by someone else.11
4442152201Natural active immunity_______ _____ ______ from an infection produced by the host examples- measles, mumps, or chicken pox.12
4442152202Artificial active_____ _____ immunity from vaccination. Ex. Diphtheria toxin.13
4442152203Natural passive immunity_______ _______ ______ transfer in vivo(mother to infant) not produced by infant. Ex: breast milk14
4442152204Artificial passive______ _____ infusion of serum or plasma with antibodies not produced by host (example tetanus antitoxin given after stepping on a rusty nail).15
4442152205Age, nutrition, vitamins, minerals, stress and hormonesFactors affecting the immune response are what 6 things?16
4442152206Cellular defense mechanismsInternal defense utilizes ______ ______ _____. Examples-Neutrophils.17
4442152207Chronic inflammationTissue damage and loss of function may result from _______ _______.18
4442152208C-Reactivate Protein___ ______ _____ is the best indicator of acute inflammation.19
4442152209OpsoninThe major function of C-Reactivate Protein (CRP) is it acts as an ______.20
4442152210Heart attack, Rheumatoid arthritis, inflammatoryMeasurement of CRP levels could be used for: Assess the risk of a _____ ____. Flare up of ______ _____. Detect an _________ response.21
4442152211InflammationCRP is a protein that only changes in concentration significantly in response to _______ and is not delectable when there is no ______.22
4442152212NeutrophilsActions of myeloid cells include ______.23
4442152213Toll-like receptorsAn additional mechanism recently discovered on certain cells is _____-_____ ________.24
4442152214Toll_______ is a protein that plays an important role in antifungal immunity in the adult.25
4442152215Neutrophils_______ are very effective at phagocytosis because of the chemicals and enzymes they contain.26
4442152216Eosinophils_________ are involved in the immune response against multicellular parasites.27
4442152217Monocytes, macrophages_______ are effective at after about 70 hours they migrate to the tissues and become _______.28
4442152218Diapedsis_______ is neutrophils squeezing through endothelial cells to leave the circulation and enter tissues.29
4442152219Opsonization_________ enhances phagocytosis30
4442152220Opsonins______ are serum proteins that attach to a foreign substance and help prepare it for phagocytosis.31
4442152221C-Reactivate Protein, Complement components, and antibodiesExamples of opsonins include what 3 things?32
4442152222Cellular defense mechanismsLymphocytes, Macrophages, Mast cells, and Dendritic cells are _____ _____ _____.33
4442152223Antibody production and cell to cell immunity (combat)Lymphocytes are not considered part of natural immunity because the function in what two things?34
4442152224Lymph nodesImmune response to foreign antigen in the tissue mainly occur in the _____ _____.35
4442152225Neutrophils_______ are the primary cell involved in the acute inflammatory response.36
4442152226Chemotaxis________ is the process where phagocytic cells are attracted toward a substance.37
4442152227Stem cells, bone marrowAll lymphocytes are created from ____ ____ in the ____ ____ and change into different groups in the primary lymphoid organs.38
4442152228Bone marrow and thymusThe primary lymphoid organs in humans are what two organs?39
4442152229Lymphopoiesis_________ or reproduction of lymphocytes occurs in the secondary tissue but this is strictly dependant on antigenic stimulation.40
4442152230Spleen_______ is the primary site of antigen trapping and presentation to immune cells.41
4442152231Lymph nodes_______ ______ are located along lymphatic ducts and serve as central collecting points for lymph fluid from surrounding tissues.42
4442152232Drainage, T, B, 1, 25Characteristics of a lymph node: filters ________ from tissues, colonized with __ and ___cells. Between __ and ___ mm in size.43
4442152233Dendritic cells_______ _____ exhibit a large number of receptors for antibody and complement and help to capture antigen to present to T and B cells.44
4442152234Memory cells, humor, antibodyB cells differentiate into _____ _____ and plasma cells are responsible for _____ immunity or ______ formation.45
4442152235Mature naive B cellWhat cells have complete IgM molecules?46
4442152236IgDIn addition to IgM, all mature B cells exhibit ____, another class of antibody molecule, on their surface.47
4442152237Memory, antibody-secretingIf a B cells is stimulated by antigen it eventually forms ______ cells and ______-______ plasma cells.48
4442152238Memory lymphocyteA ______ ______ can recall previous contact with a particular antigen so that subsequent exposure leads to a more rapid and more effective immune response than the first encounter.49
4448282436Drainage, T, B, 1, 25Characteristics of a lymph node: filters ________ from tissues, colonized with __ and ___cells. Between __ and ___ mm in size.50
4448282623Dendritic cells_______ _____ exhibit a large number of receptors for antibody and complement and help to capture antigen to present to T and B cells.51
4448282624Memory cells, humor, antibodyB cells differentiate into _____ _____ and plasma cells are responsible for _____ immunity or ______ formation.52
4448282625Mature naive B cellWhat cells have complete IgM molecules?53
4448282626IgDIn addition to IgM, all mature B cells exhibit ____, another class of antibody molecule, on their surface.54
4448282629CD4+_______ cells, termed T-helper cells. They recognize antigen and MAC class OIT exogenous peptide (protein).55
4448282630CD8+______ cells are termed T-cytotoxic cells.56
4448282631CD4, CD8An immature T cell expresses both ___ and ____.57
4448282632Nk____ cells are triggered by lack of MHC antigens, sometimes referred to as recognition of "missing self".58
4448282633ApoptosisWhat does kill target cells mean?59
4448282634Adjuvant_________ is a substance used to enhance antibody formation.60
4448282635Antigen______ refers to a substance that reacts with antibody or sensitized T cells61
4448282636AntibodyAn _____ attacks the antigen.62
4448282637Influences of an immune response.Age, Overall health and proper nutrition, Dose of antigen, Route of inoculation, and Genetic predisposition are all considered?63
4448282638Epitopes_____ are also called antigenic determinant. Key portion of the immunogen that can enter into Ab-Ag reactions.64
4448282639Haptens______are nonimmunogenic materials too small to illicit an immune response unless combined with a carrier to create new antigenic determinants.65
4448282788Alloantigens_______are from other members of the host species.66
4448282789Heterophile_______ antigens exists in unrelated plants of animals that are either identical or closely related in structure and the antibody in humans will cross-react with the antigens. Antigens not belonging to the host species but from a different species that react in humans.67
4448282790CodominantGenes that are expressed whether they are in the heterozygous or homozygous state is called?68
4448282791CD4 (helper) T cellClass II molecules present antigen to ____ __ ___.69
4448282792Antibody formationIf binding occurs with a T cell receptor on a CD4-positive T cell, thr T helper cell recruits and triggers B cell response, resulting in _____ _____.70
4448282793AntibodiesIn other words, the T cells tell B cells to make _____.71
4498418493Cytotoxic T cellsWhat cells are the primary immune response against viruses?72

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