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| 6065219660 | Pathophysiology of Iron Deficiency Anemia : | - Most common world-wide - Caused by decreased production of RBCs | 0 | |
| 6065228691 | Causes of Iron Deficiency Anemia? | - Blood Loss - Poor GI Absorption of Iron - Inadequate Diet | 1 | |
| 6065241467 | What are RBCs like in a person with Iron Deficiency Anemia? | RBCs are microlytic (Small) | 2 | |
| 6065244632 | S&S of Iron Deficiency Anemia: | - Weakness - Pallor - Fatigue - Reduced Exercise Tolerance - Fissures on corners of mouth - Serrum Ferritin (tests amount of free iron in plasma) is low or < 10ng/mL | 3 | |
| 6065275330 | Management of Iron Deficiency Anemia: | - Increasing oral intake of iron from food (Red meat, Organ meat, Egg yolks, Kidney beans, Leafy Greens, & Raisins) - If iron losses are mild, oral iron supplements used such as ferrous sulfate | 4 | |
| 6065293930 | When should iron supplements be taken? | Between meals for better absorption and to reduce GI distress | 5 | |
| 6065301378 | What is the treatment for severe iron deficiency anemia? | Iron solutions such as Iron Dextran (Dexferrum) can be given parenterally | 6 | |
| 6065313619 | Pathophysiology of Vitamin B12 Deficiency Anemia: | - Caused by decreased production of RBCs - Failure to activate the enzyme that moves folic acid into precursor RBC so that cell division and growth into functional RBCs can occur - Known as megaloblastic anemia | 7 | |
| 6065336667 | What are RBCs like in a person with Vitamin B12 Deficiency Anemia? | RBCs are Macrolytic (Big) | 8 | |
| 6065352011 | Causes of Vitamin B12 Deficiency Anemia? | - Vegan Diets or Diets lacking dairy - Small Bowel Resection - Chronic Diarrhea - Diverticula - Tapeworm - Overgrowth of Intestinal Bacteria | 9 | |
| 6065370922 | How does anemia resulting from failure of vitamin B12 occur? | Caused by deficiency of intrinsic factor (a substance normally secreted by gastric mucosa) which is needed fo rintestinal absorption of B12 | 10 | |
| 6065384135 | S&S of Vitamin B12 Deficiency Anemia: | - Pallor - Jaundice - Glossitis (Smooth, Beefy-Red Tongue) - Fatigue - Weight Loss - May have abnormal sensations in hands and feet As well as poor balance | 11 | |
| 6065390187 | Glossitis | Smooth, Beefy-Red Tongue |  | 12 |
| 6065419483 | Treatment of Vitamin B12 Deficiency when diet is the problem: | Increase food intake rich in vitamin B12: - Animal Proteins - Eggs - Fish - Nuts - Dairy - Dried Beans - Citrus - Leafy Greens | 13 | |
| 6065445433 | What is pernicious Anemia? | Decrease in RBCs that occurs when the intestines cannot properly absorb vitamin B12 - A type of B12 Deficiency anemia | 14 | |
| 6065439426 | What do they do with patients who have pernicious anemia? | Usually given B12 injections weekly at first and then monthly for the rest of their lives | 15 | |
| 6065461778 | Pathophysiology of Folic Acid Deficiency Anemia: | - Caused by Decreased Production of RBCs - Manifestations similar to vitamin B12 deficiency except for nervous system functions normally - Develops slowly | 16 | |
| 6066260933 | Common Causes of Folic Acid Deficiency Anemia: | - Poor Nutrition (Diet lacking leafy greens, liver, yeast, citrus, dried beans, & nuts) ^ Most common cause - Malabsorption (Crohn's Disease) ^ Second most common cause - Drugs (Anticonvulsants/ Oral Contraceptives) Contribute tp folic acid deficiency and anemia | 17 | |
| 6066303676 | Prevention for Folic Acid Deficiency Anemia Begins by: | - Identifying high-risk patients such as older patients with alcoholism; - Patients at risk for malnutrition - Patient with increased folic acid requirements - Managed with | 18 | |
| 6066323171 | How is folic acid deficiency anemia managed? | managed with scheduled folic acid replacement therapy | 19 | |
| 6066450886 | Pathophysiology of Aplastic Anemia: | - Caused by Decreased Production of RBCs - Deficiency of circulating RBCs because failure of the bone marrow to produce cells - May follow a viral infection - Most common hereditary form od the disease is known as "Fanconi's Anemia" | 20 | |
| 6066457662 | Common Causes of Aplastic Anemia: | - Injury to the immature precursor cell for the RBC - Can occur with leukopenia & Thrombocytopenia - Onset is slow or rapid | 21 | |
| 6066477725 | What is the most common type of Aplastic Anemia? | - Long-term exposure to toxic agents, drugs, ionizing radiation, or infection - Oftentimes the cause is unknown | 22 | |
| 6066506322 | S&S of Aplastic Anemia: | - CBC shows macrocytic anemia, leukopenia, &t thrombocytopenia - Bone marrow biopsy may show replacement of cell-forming marrow with fat - Infection is common | 23 | |
| 6066536250 | Are blood transfusions commonly used with Aplastic Anemia? | Blood transfusions are used only when the anemia causes disability or when bleeding is life-threatening due to low platelet count * Unnecessary transfusion increases chances of developing immune reactions to platelets and shorts the lifespan of the transfused cell | 24 | |
| 6066598439 | What is the most successful treatment for patients with aplastic anemia? | - Hematopoietic stem cell transplantation with donor cells is the most successful method of treatment - Cost, availability, & complications limit this treatment | 25 | |
| 6066755727 | Does immunosuppressive therapy help patients with aplastic anemia? | - Helps significantly with patients who have the type of aplastic anemia where a disease course is similar to that of autoimmune problems - Drugs such as prednisone, antithymocyte globulin (ATG), & Cyclosporine A (Sandimmune) have resulted in partial or complete remissions | 26 | |
| 6066937854 | What drugs do they use for moderate aplastic anemia? | Daclizumab (Zenapax- Improved both blood counts & transfusion requirements | 27 | |
| 6066949225 | Why would a splenectomy be needed in a patient with aplastic anemia? | May be needed if the enlarged spleen is destroying normal RBCs or suppressing their development | 28 | |
| 6066966994 | For those with aplastic anemia that cannot undergo treatment or find a suitable donor what is the next best therapy? | Immunosuppressive therapy | 29 |
