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Leukocytes Flashcards

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6389660945What are leukocytes responsible for?Responsible for the recognition, response, and removal of foreign material and damaged cells from the body0
6389674842Leukocytes are the major participants in both ______________ & _____________ system response mechanismsinflammatory & immune1
6389681641The majority of leukocytes in the body are not freely circulating : T/FTrue2
6389691739Proliferation PoolBone marrow3
6389692867Storage PoolSpleen, bone marrow4
6389698199Circulating PoolBlood stream5
6389700030Marginal PoolWalls of small vessels6
6389704773Tissue PoolVarious tissues of the body -May contain up to 75% of leukocytes within the vasculature7
6389715498Cells are not allowed to shift between pools : T/FFalse -cells shift between pools as needed8
6389782864Leukocyte response to disease for certain animals:Dog: Dramatic elevation (3-5x) Cat: Less dramatic Horse: moderate response Cow: Less responsive than horse9
6389790622LeukocytosisIncreased WBC10
6389792647LeukopeniaDecreased WBC11
6389796134Leukocytes are divided into _____________ & ______________.Granulocytes & Agranulocytes12
6389799687GranulocytesCells whose cytoplasm contain granules "Phil eats Grains"13
6389804835Examples of Granulocytes:Neutrophils Eosinophils Basophils14
6389806679AgranulocytesCells whose cytoplasm does not contain granules "No grains in Sight (cyte)"15
6389814771Examples of AgranulocytesLymphocytes Monocytes16
6389822853Leukocytes Stages17
6389827126NeutrophilsMature in 3-6 days Segmented neutrophils released from bone marrow Replaced 2x daily in the dog (short life span)18
6389849582What is the most numerous Leukocyte in the dog, cat, and horse?Neutrophil19
6389852569What is the function of Neutrophils?Phagocytosis20
6389916989Neutrophils are often destroyed while engulfing and digesting the bacteria : T/FTrue -PUS : Purulent discharge21
6389969900How long do neutrophils remain in circulation before entering tissue?10 hours22
6389980569Another term for immature neutrophilsBand neutrophils23
6390016749Neutrophils will be increased in acute bacterial infections but may decrease in viral infections : T/FTrue24
6390037546Avians, reptiles, some fish, some mammals have ______________.Heterophils25
6390039732Canine neutrophil26
6390041654Feline neutrophil27
6390059019Equine Neutrophil28
6390071155Bovine Neutrophil29
6390073516EosinophilsProduction similar to neutrophils Maturation time = 1 week Only stays in circulation for few hours30
6390089588Increased number of Eosinophils may be due to ....Immune response to parasites or Allergic reaction31
6390095279Canine Eosinophil32
6390100331Feline Eosinophils33
6390109488What are basophils similar to?Mast Cells -Granules contain Heparin & histamine, like mast cells34
6390115989How are basophils & mast cells different?Basophils are in circulation Mast cells reside in tissue35
6390123880Basophil cytoplasmContains large blue-black granules that often obscure the nucleus36
6390157650What is the largest of the leukocytes?Monocytes (Macrophages)37
6390160504Where are monocytes produced?Bone marrow38
6390166282Monocytes are pleomorphic (various shapes), but not segmented : T/FTrue39
6390169069Monocytes are mature when released into circulation : T/FFalse -monocytes are not mature40
6390174348Once Monocytes enter tissues they are now called ____________Macrophages41
6392342729What are the functions of MonocytesDefense & removal of damaged cells -phagocytosis -handles more difficult pathogens42
6392360615Where are large numbers of macrophages located?Liver, Spleen, & Lymph nodes43
6392368820Macrophages are _____to arrive at sire of infection than neutrophils, but persist ______ longer in tissueSlower & Longer44
6392372326__________ are usually elevated in cases of chronic diseasesMonocytes45
6392373462Monocyte46
6392374972LymphocytesMake up "specific immune system" Respond specifically to antigens Kills infected cells & produce antibodies against pathogens47
6392393803Most numerous leukocytes are in ____________.Ruminants48
6392398599Three general types of lymphocytes1. T-cells 2. B-cells 3. Natural killer cells49
6392406399Where are Tcells found?Thymus50
6392406932Where are Bcells found?Bone marrow51
6392407534Where are natural killer cells found?Bone marrow & thymus52
6392409636Lymphopoiesis53
6392414234What is the only leukocyte with NO phagocytic function?Lymphocyte54
6392425536What is the only leukocyte that re-enters circulation after entering tissue?Lymphocytes55
6392445207Were lymphocytes begin development?Bone marrow56
6392470557How are mature B-cells & T-cells activated?By a cell carrying the antigen that binds to the specific antigen receptor on the lymphocyte surface57
6392478362Memory cellsLymphocytes that quickly recognize the antigen the next time the animal is exposed58
6392486888NK CellsDo not have specific antigen receptors Kills cells that are infected with virus or neoplastic cells59
6392505232Increased numbers of lymphocytes often indicates a _______ infection or a ______ infectionBacterial or Viral60
6392519348lymphocytes are often mistaken for ____ _____ ____.Red blood Cells61
6392523516that is the Humoral Response centered on?B-Lymphocytes62
6392542427What are antibodies?Large protein molecules in shape of a Y63
6392544646What is Cell Mediated Immune Response centered on?T-Lymphocytes64
6392545693T- Lymphocytes subsets1. Helper Cells 2. Suppressor Cells 3. Null Cells (NK)65
6392552979T- Lymphocytes are activated by the presence of __________.Antigens66
6392560480What does Cell Mediated Immune Response require?Requires that the macrophage "presents" the antigen to the T-cell67
6392568952Cell Mediated = __ Lymphocytes Humoral = __ LymphocytesT & B68

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