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Mitosis - AP Biology Flashcards

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6086797002G1 PhaseFirst stage of interphase in which cell grows and performs its normal functions. Cell is diploid.0
6086797003G0 PhaseCell is performing its normal functions, but has left the cell cycle and is not dividing.1
6086797004S PhaseThe synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated.2
6086797005G2 PhaseLast stage of interphase in which cell grows and performs its normal functions. Cell is tetraploid.3
6086797006InterphaseCell grows, performs its normal functions, and prepares for division; consists of G1, S, and G2 phases4
6086797008Align - MetaphasePhase of mitosis in which spindle fibers help chromosomes line up on the midline of the cell.5
6086797009Separate - AnaphasePhase of mitosis in which the chromosomes separate and move to opposite ends of the cell.6
6086797010TelophasePhase of mitosis during which chromosomes uncoil, a nuclear envelope returns around the chromatin, and a nucleolus becomes visible in each daughter cell"7
6086797011CytokinesisAt the end of telophase, actin fibers form an equator around the cell and contract, separating the cytoplasm into two daughter cells.8
6086797012CentrioleA paired cluster of microtubules near the nucleus in animal cells. This organelle organizes spindle fibers during mitosis.9
6086797013CentromereRegion of a chromosome where the two sister chromatids attach to one another. Contains the kinetochore.10
6086797014KinetochoreA specialized region on the centromere that links each sister chromatid to the mitotic spindle.11
6086797015Spindle FibersMade of microtubules that connect centrioles to kinetochores of chromosomes and that separate sister (mitosis) or homologous (meiosis) chromosomes during cell division12
6086797016ChromosomeA threadlike, gene-carrying structure found in the nucleus. Each chromosome consists of one very long DNA molecule and associated proteins.13
6086797017ChromatidOne of two identical "sister" parts of a duplicated chromosome.14
6086797018HaploidA cell with only one copy of each chromosome.15
6086797019DiploidA cell with two copies of each chromosome.16
6086797022Cyclin-Dependent Kinase (CDK)A group of protein kinases that are activated by the formation of a complex with a cyclin and are involved in the regulation of the cell cycle. Only active when bound to a cyclin.17
6086797023CyclinA cellular protein that occurs in a cyclically fluctuating concentration and that plays an important role in regulating the cell cycle.18
6086797026p53This tumor suppressor gene causes cell cycle arrest in G1, providing time for DNA repair. If repair is successful, cells re-enter the cycle. If unsuccessful, apoptosis. Damage to this protein can cause cancer.19
6086797027Proto-oncogeneA normal cellular gene corresponding to an oncogene; a gene with a potential to cause cancer but that requires some alteration to become an oncogene.20
6086797028Tumor Suppressor GeneA gene whose protein products inhibit cell division, thereby preventing uncontrolled cell growth. Mutations in this gene can cause cancer.21
6086797029KinaseAn enzyme that adds a phosphate group to a protein. Phosphorylation usually activates protein activity.22
6086797030PhosphataseAn enzyme that removes a phosphate group from a protein. Phosphorylation usually activates protein activity.23
6086840324G2 checkpointmistakes in DNA, proteins check that cell is large enough to divide24
6086842997M checkpoint(spindle assembly checkpoint) mitosis will not continue if chromosomes are not aligned properly25

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