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| 3851515673 | DNA Viruses | Hep, Herpes, Adenoviridae, Poxviridae | 0 | |
| 3851521756 | Virus inner shell called, made of | Capsid (holds DNA or RNA), protein | 1 | |
| 3851523547 | Steps for Self-Replication | Adsorption, Penetration and Uncoating, Biosynthesis, Maturation and Release (exocytosis or lysis( | 2 | |
| 3851531036 | Envelope of virus is made of | lipid bilayer | 3 | |
| 3851555669 | Acyclovir and Valacyclovir: Effective against | Herpes virus | 4 | |
| 3851556901 | Acyclovir and Valacyclovir: Which viruses | Varicella zoster, Epstein Barr | 5 | |
| 3851558663 | Acyclovir and Valacyclovir: How aadministered | topical, systemic | 6 | |
| 3851561029 | Acyclovir and Valacyclovir: MOA | Inhibits DNA replication | 7 | |
| 3851564610 | Acyclovir and Valacyclovir: Inhibits what enzyme? | DNA polymerase | 8 | |
| 3851566617 | Valacyclovir is converted in | Intestines and liver | 9 | |
| 3851574731 | Amantadine and Rimantadine: Use | Influenza A | 10 | |
| 3851577973 | Amantadine and Rimantadine: MOA | Block un-coating and block assembly of vital components | 11 | |
| 3851581848 | Amantadine and Rimantadine: Adverse Effects | CNS, OD- seizures | 12 | |
| 3851587138 | Famiciclovir and Peniciclovir: Use | Cold sores (Herpes Zoster/Genital Herpes) | 13 | |
| 3851591832 | What 2 drugs are activated within infected cells and then inhibit viral DNA synthesis/replication? | Acyclovir (Valacyclovir) and Penicyclovir (Famiciclovir) | 14 | |
| 3851602331 | Adverse Effects Famiciclovir and Peniciclovir | Irritation over site (topical), Some HA, dizziness, GI (oral) | 15 | |
| 3851611962 | Protease Inhibitors | Inhibit HIV protease | 16 | |
| 3851613407 | Protease Inhibitors MOA | prevent cleavage of polypeptide precursors, prevents maturation | 17 | |
| 3851616951 | Protease Inhibitors Adverse Effects | Lipodystrophy, insulin resistance, metabolic syndrome | 18 | |
| 3851632698 | Protease inhibitors: Combine with __ to have therapeutic effect at a lower dose | Ritonair | 19 | |
| 3851636979 | Reverse Transcriptase Inhibitors: Use | HIV-1 | 20 | |
| 3851638586 | Reverse Transcriptase Inhibitors: MOA | Act on HIV reverse transcriptase (reduce proliferation, halt progress) | 21 | |
| 3851652289 | NRTI: inhibit, act as a | RNA to DNA, false nucleic acid | 22 | |
| 3851660814 | NNRTI: act on | different site for same enzyme | 23 | |
| 3851662240 | RTI Adverse effect | blood dyscrasias (anemia and zidovudine) | 24 | |
| 3851664171 | NRTI Adverse Effect | Myopathies, peripheral neuropathies | 25 | |
| 3851665656 | NNRTI Adverse Effect | Skin rashes | 26 | |
| 3851670993 | Ribavarin Use | RSV (respiratory syncythial virus), Influenza A and B, Hep C (combine with interferons) | 27 | |
| 3851673590 | Ribavarin MOA | Inhalation, Impair mRNA synthesis | 28 | |
| 3851675001 | Ribavarin Adverse Effects | Conjunctivitis- contact with eyes | 29 | |
| 3851681414 | Interferons activate __ to limit excess cell division | lymphocytes and cytotoxic cells | 30 | |
| 3851684714 | Type 1 Interferons (alpha and beta) combat | Virus | 31 | |
| 3851686941 | Type 2 (gamma) produces__ and combats __ | T lymphocytes, inflammation | 32 | |
| 3851693869 | Role of Oncogenes | Interferons inhibit specific gene regulatory segments of tumor cells, this stops excess proliferation and lack of cell differentiation (anti-cancer) | 33 | |
| 3851696602 | Type 1 Interferons helpful for | Helpful for Hep B and C, MS type 1 | 34 | |
| 3851705347 | Adverse effects interferons | Flu-like, behavioral | 35 | |
| 3851707643 | Vaccines are __-like | antigen | 36 | |
| 3851709192 | HIV and AIDS belong to __ family | retrovirus | 37 | |
| 3851711035 | HIV 1 or 2 is more prevalent | 1 | 38 | |
| 3851712722 | HIV has what neurological involvement? | neuropathies, myopathies | 39 | |
| 3851712723 | Tx | HAART | 40 | |
| 3851713847 | HAART example | 2 RTI and 1 protease inhibitor | 41 | |
| 3851716802 | HAART reduces | viral load | 42 | |
| 3851720056 | even if viral load decreases, there can still be some in __ and other reservoirs | T cells | 43 |
