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Neurochemistry

Cell Communication

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Cell Biology Objectives and Worksheet 2: Cell-to-Cell and Signal Transduction Name____________________ Objectives: Write out material in your course notebook. Cell to cell communication and signal transduction. Distinguish among types of cell-to-cell communication {autocrine, paracrine, endocrine, cytokine, cell surface markers, neurotransmitter} List major classes of receptors. Explain or diagram the specific structural components of the types. List and describe the components of signal transduction and the molecules involved. Write out specific second messenger signal transduction pathways (see tables 6.1 & 6.2). Define each of the following and predict their effect on signal transduction: agonist and antagonist for one receptor

AP Biology Notes Chapter 11 (Campbell/Reece)

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Chapter 11 ? Cell Communication Overview: The Cellular Internet The trillions of cells in a multicellular organism must communicate with each other to coordinate their activities. There are networks of communication between cells ? can be very complicated There are Universal Mechanisms of cellular regulation (and communication) ? this is further evidence that all life is related (evolutionarily). 11.1 External Signals are converted to responses within the cell What do the cells say to each other? Evolution of Cell Signaling: One thing they talk about is sex/reproduction. Example: Yeast cells: (figure 11.2) There are two genders or mating types ? ?a? and ?alpha? Type ?a? cells secrete ?a? factor which can bind on specific receptors on the ?alpha? cell

Drugs and neurotransmitter effects

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Drug Effects Drug Type Neurotransmitters involved Similar Drugs Cocaine Energetic, euphoric, heart damage, appetite suppression Stimulant Dopamine Agonist (Dopamine uptake inhibitor) Heroin/ morphine/ opium Pain relief, euphoria, relaxed, short term memory loss Narcotic Activates all opiate receptors Hydrocodone, oxycontin, Demerol, methadone Marijuana Calm, happy, hungry, appreciate abstract thoughts Cannabis Cannabinoid receptors Cigarettes Rapid heartbeat; Increased blood pressure; Rapid, shallow breathing; initially causes a rapid release of?adrenaline Nicotine Acetylcholine receptor agonist Coffee Alertness, appetite suppression, headache relief (vasodilator) Caffeine Adenosine receptor agonist
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