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Molecular Bionumbers Notes

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Useful fundamental numbers in molecular biology The numbers quoted here were extracted from the literature. They should only serve as ?rule of thumb? values. Consult the full references to learn about the specific system under study, growth conditions, measurement method etc. Full references at: www.bioNumbers.org Cell sizes: Bacteria (e.coli): ~1mm diameter, 2mm length, ~1mm3 in volume; 109cells/ml in an overnight culture (OD600~1) Yeast (Saccharomyces cerevisiae): ~5 mm diameter, ~50 mm3 in volume Mammalian (HELA) cell - ~2,000 mm3 in volume, adherent cell on a slide ~20 mm diameter ? ~100,000 cells in a confluent well of a 96 multiwell plate Organelles and cell constituents: Mammalian cell nucleus ~10 micron diameter

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